Page last updated: 2024-10-26

ebselen and Acute Disease

ebselen has been researched along with Acute Disease in 5 studies

ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"This study evaluated the effects of the seleno-organic substance Ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one] in two models of acute hemorrhagic and acute edematous pancreatitis."7.68Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. ( Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K, 1991)
"This study evaluated the effects of the seleno-organic substance Ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one] in two models of acute hemorrhagic and acute edematous pancreatitis."3.68Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. ( Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K, 1991)
"Treatment with ebselen (10 mg/kg) significantly decreased pulmonary inflammation as indicated by the albumin concentration and the number of neutrophils in the bronchoalveolar lavage fluid 18 h after the ozone exposure."1.31Ebselen decreases ozone-induced pulmonary inflammation in rats. ( Hashimoto, K; Hirano, K; Ishii, Y; Masuyama, K; Mochizuki, M; Morishima, Y; Nomura, A; Sagai, M; Sakamoto, T; Sekizawa, K; Uchida, Y, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agbani, EO1
Coats, P1
Wadsworth, RM1
Ohta, Y1
Kobayashi, T1
Inui, K1
Yoshino, J1
Nakazawa, S1
Yamaguchi, T1
Sano, K1
Takakura, K1
Saito, I1
Shinohara, Y1
Asano, T1
Yasuhara, H1
Ishii, Y1
Hashimoto, K1
Hirano, K1
Morishima, Y1
Mochizuki, M1
Masuyama, K1
Nomura, A1
Sakamoto, T1
Uchida, Y1
Sagai, M1
Sekizawa, K1
Niederau, C1
Ude, K1
Niederau, M1
Lüthen, R1
Strohmeyer, G1
Ferrell, LD1
Grendell, JH1

Trials

1 trial available for ebselen and Acute Disease

ArticleYear
Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group.
    Stroke, 1998, Volume: 29, Issue:1

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-S

1998

Other Studies

4 other studies available for ebselen and Acute Disease

ArticleYear
Acute hypoxia stimulates intracellular peroxynitrite formation associated with pulmonary artery smooth muscle cell proliferation.
    Journal of cardiovascular pharmacology, 2011, Volume: 57, Issue:5

    Topics: Acute Disease; Animals; Azoles; Cattle; Cell Culture Techniques; Cell Hypoxia; Cell Proliferation; C

2011
Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.
    Japanese journal of pharmacology, 2002, Volume: 90, Issue:4

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Azoles; Dose-Response Relationship,

2002
Ebselen decreases ozone-induced pulmonary inflammation in rats.
    Lung, 2000, Volume: 178, Issue:4

    Topics: Acute Disease; Albumins; Analysis of Variance; Animals; Antioxidants; Azoles; Blotting, Northern; Br

2000
Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis.
    Pancreas, 1991, Volume: 6, Issue:3

    Topics: Acute Disease; Amylases; Animals; Azoles; Ceruletide; Choline Deficiency; Diet; Disease Models, Anim

1991