ebselen has been researched along with Acute Confusional Senile Dementia in 12 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ebselen reversed the increase in the hepatic GST activity of the STZ-injected mice." | 1.56 | Ebselen reversed peripheral oxidative stress induced by a mouse model of sporadic Alzheimer's disease. ( Klann, IP; Martini, F; Nogueira, CW; Rosa, SG, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, Z | 3 |
| Sheng, J | 2 |
| Sun, Y | 2 |
| Lu, C | 1 |
| Yan, J | 1 |
| Liu, A | 1 |
| Luo, HB | 1 |
| Huang, L | 4 |
| Li, X | 5 |
| Liang, L | 1 |
| Pang, Y | 1 |
| Li, J | 1 |
| Wang, B | 1 |
| Wang, Z | 2 |
| Chen, H | 1 |
| Lu, CJ | 1 |
| Barbosa, FAR | 1 |
| Canto, RFS | 1 |
| Saba, S | 1 |
| Rafique, J | 1 |
| Braga, AL | 1 |
| Roldán-Peña, JM | 1 |
| Alejandre-Ramos, D | 1 |
| López, Ó | 1 |
| Maya, I | 1 |
| Lagunes, I | 1 |
| Padrón, JM | 1 |
| Peña-Altamira, LE | 1 |
| Bartolini, M | 1 |
| Monti, B | 1 |
| Bolognesi, ML | 1 |
| Fernández-Bolaños, JG | 1 |
| Hu, J | 1 |
| An, B | 1 |
| Pan, T | 1 |
| Li, Z | 1 |
| Qu, L | 1 |
| Ji, L | 1 |
| Wang, C | 1 |
| Luo, H | 1 |
| Li, S | 1 |
| Peng, W | 1 |
| Yin, F | 1 |
| Lu, D | 1 |
| Liu, X | 1 |
| Kong, L | 1 |
| Wang, X | 1 |
| Klann, IP | 2 |
| Martini, F | 2 |
| Rosa, SG | 2 |
| Nogueira, CW | 2 |
| Xie, Y | 1 |
| Tan, Y | 1 |
| Zheng, Y | 1 |
| Du, X | 1 |
| Liu, Q | 1 |
| Fulco, BCW | 1 |
| Carvalho, FB | 1 |
| Rahmeier, FL | 1 |
| Fernandes, MC | 1 |
| Wang, Y | 1 |
| Li, W | 1 |
| Liu, Z | 1 |
| Wu, R | 1 |
| Bastianetto, S | 1 |
| Zheng, WH | 1 |
| Quirion, R | 1 |
12 other studies available for ebselen and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Azoles; Butyrylcholinestera | 2013 |
Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Azoles; Biocompatible Materials; Butyrylcholi | 2014 |
Synthesis and evaluation of 8-hydroxyquinolin derivatives substituted with (benzo[d][1,2]selenazol-3(2H)-one) as effective inhibitor of metal-induced Aβ aggregation and antioxidant.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Copper; Drug Design; Hu | 2016 |
Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Esters | 2016 |
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents; Anti | 2017 |
Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Azoles; Biomimetic Materials; Drug Design; Free Radical Scavengers; Glut | 2018 |
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Aspart | 2021 |
Ebselen reversed peripheral oxidative stress induced by a mouse model of sporadic Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Azoles; Biomarkers; Catalysis; Disease Models, Animal; Gas | 2020 |
Ebselen ameliorates β-amyloid pathology, tau pathology, and cognitive impairment in triple-transgenic Alzheimer's disease mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Azoles; Cell Line, Tumor; Cell Survival; Cognitio | 2017 |
A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Azoles; Disease Models, Animal; Isoindoles; Mal | 2019 |
Computer-assisted designed "selenoxy-chinolin": a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Azoles; Biocompatible Materials; Bl | 2015 |
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C.
Topics: Alkaloids; Alzheimer Disease; Animals; Antioxidants; Azoles; Benzophenanthridines; Brain Ischemia; C | 2000 |