Page last updated: 2024-10-26

ebastine and Irritable Bowel Syndrome

ebastine has been researched along with Irritable Bowel Syndrome in 3 studies

Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.

Research Excerpts

ExcerptRelevanceReference
" Ebastine, an antagonist of HRH1, reduced visceral hypersensitivity, symptoms, and abdominal pain in patients with IBS."5.22Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome. ( Alpizar, YA; Augustijns, P; Balemans, D; Belmans, A; Boeckxstaens, GE; Bulmer, DC; Carmeliet, P; Cibert-Goton, V; Cirillo, C; Dooley, J; Ghesquière, B; Hellings, PW; Kortekaas, I; Liston, A; Mols, R; Nasser, Y; Peetermans, WE; Rutgeerts, P; Talavera, K; Valdez-Morales, EE; Van der Merwe, S; Van Veldhoven, PP; Van Wanrooy, S; Vanbrabant, W; Vanden Berghe, P; Vanner, S; Vermeire, S; Wouters, MM, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stanisor, OI1
van Diest, SA1
Yu, Z1
Welting, O1
Bekkali, N1
Shi, J1
de Jonge, WJ1
Boeckxstaens, GE2
van den Wijngaard, RM1
Wouters, MM1
Balemans, D1
Van Wanrooy, S1
Dooley, J1
Cibert-Goton, V1
Alpizar, YA1
Valdez-Morales, EE1
Nasser, Y1
Van Veldhoven, PP1
Vanbrabant, W1
Van der Merwe, S1
Mols, R1
Ghesquière, B1
Cirillo, C1
Kortekaas, I1
Carmeliet, P1
Peetermans, WE1
Vermeire, S1
Rutgeerts, P1
Augustijns, P1
Hellings, PW1
Belmans, A1
Vanner, S1
Bulmer, DC1
Talavera, K1
Vanden Berghe, P1
Liston, A1
Camilleri, M1
Boeckxstaens, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IBS Treatment With H1-receptor Antagonists[NCT01144832]Phase 455 participants (Actual)Interventional2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ebastine and Irritable Bowel Syndrome

ArticleYear
Dietary and pharmacological treatment of abdominal pain in IBS.
    Gut, 2017, Volume: 66, Issue:5

    Topics: Abdominal Pain; Anti-Infective Agents; Antidepressive Agents; Butyrophenones; Dipeptides; GABA Agent

2017

Trials

1 trial available for ebastine and Irritable Bowel Syndrome

ArticleYear
Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome.
    Gastroenterology, 2016, Volume: 150, Issue:4

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Analgesics; Belgium; Biopsy; Butyrophenones; Calcium Signal

2016

Other Studies

1 other study available for ebastine and Irritable Bowel Syndrome

ArticleYear
Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonists.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Blotting, Western; Butyrophenones; Dose-Response Relationship, Drug; Histamine H1 Antagonis

2013