ebastine has been researched along with Heart Diseases in 5 studies
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Recent clinical evidence shows that some of the early prototypes in this class, namely terfenadine and astemizole, have the potential for producing torsade de pointes, a rare form of ventricular arrhythmia that is life-threatening." | 7.69 | Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. ( del Prado, M; Egan, RW; Hey, JA; Kreutner, W, 1996) |
| "Although the new second-generation nonsedative antihistamines terfenadine and astemizole were launched as highly selective and specific H(1)-receptor antagonists, they were later found to cause prolongation of the QT-interval and severe cardiac arrhythmias." | 4.81 | Cardiotoxicity of new antihistamines and cisapride. ( Paakkari, I, 2002) |
| " Recent clinical evidence shows that some of the early prototypes in this class, namely terfenadine and astemizole, have the potential for producing torsade de pointes, a rare form of ventricular arrhythmia that is life-threatening." | 3.69 | Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. ( del Prado, M; Egan, RW; Hey, JA; Kreutner, W, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hey, JA | 1 |
| del Prado, M | 1 |
| Kreutner, W | 1 |
| Egan, RW | 1 |
| Roberts, DJ | 2 |
| Moss, AJ | 1 |
| Morganroth, J | 1 |
| Paakkari, I | 1 |
3 reviews available for ebastine and Heart Diseases
| Article | Year |
|---|---|
Towards the optimal antihistamine: studies with ebastine.
Topics: Animals; Bronchoconstriction; Butyrophenones; Guinea Pigs; Heart Diseases; Histamine H1 Antagonists; | 1998 |
Cardiac effects of ebastine and other antihistamines in humans.
Topics: Aged; Butyrophenones; Child; Drug Interactions; Electrocardiography; Heart Diseases; Histamine H1 An | 1999 |
Cardiotoxicity of new antihistamines and cisapride.
Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Disea | 2002 |
2 other studies available for ebastine and Heart Diseases
| Article | Year |
|---|---|
Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes.
Topics: Animals; Butyrophenones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; | 1996 |
Cardiotoxicity of second-generation antihistamines.
Topics: Astemizole; Butyrophenones; Heart Diseases; Histamine H1 Antagonists; Humans; Piperidines; Terfenadi | 1999 |