ebastine has been researched along with Atopic Hypersensitivity in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This comparative study in mosquito-bite-sensitive adults shows that cetirizine and ebastine decrease significantly whealing and accompanying pruritus, and that cetirizine seems to be the most effective against pruritus." | 5.10 | Comparison of cetirizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy. ( Burri, P; Karppinen, A; Kautiainen, H; Petman, L; Reunala, T, 2002) |
| "001), with an enormous reduction in the oral bioavailability of ebastine and significantly reduced histamine-induced skin reactions." | 2.75 | Itraconazole and rifampin alter significantly the disposition and antihistamine effect of ebastine and its metabolites in healthy participants. ( Cha, IJ; Lee, SS; Liu, KH; Shin, JG; Shon, JH; Yeo, CW, 2010) |
| " In conclusion, this study shows that, at the end of the conventional dosing interval, ebastine 10 mg and cetirizine 10 mg once daily in repeated doses suppressed the histamine wheal more effectively than did loratadine 10 mg once daily or fexofenadine 60 mg twice daily." | 2.70 | Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state. ( Boyce, M; Carey, W; Luria, X; Warrington, S, 2002) |
| "Ebastine was no better than placebo until 4 h, but was efficacious thereafter until 24 h." | 2.69 | A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects. ( Danielson, L; DeVos, C; Grant, JA; Rihoux, JP, 1999) |
| " The pharmacokinetics of carebastine were linear over the dose range studied and the terminal elimination half-life was 10." | 2.66 | The pharmacokinetics, antihistamine and concentration-effect relationship of ebastine in healthy subjects. ( Liminana, R; Meredith, PA; Reid, JL; Vincent, J, 1988) |
| "Ebastine is a novel histamine H1 receptor antagonist that combines potency with a rapid onset (fast absorption) and long duration (slow elimination) of action, at least partially mediated via the formation of an acid metabolite (carebastine) that is even more potent as an antihistamine." | 2.39 | A preclinical overview of ebastine. Studies on the pharmacological properties of a novel histamine H1 receptor antagonist. ( Roberts, DJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shon, JH | 1 |
| Yeo, CW | 1 |
| Liu, KH | 1 |
| Lee, SS | 1 |
| Cha, IJ | 1 |
| Shin, JG | 1 |
| Carey, W | 1 |
| Warrington, S | 1 |
| Boyce, M | 1 |
| Luria, X | 1 |
| Roberts, DJ | 1 |
| Grant, JA | 1 |
| Danielson, L | 1 |
| Rihoux, JP | 1 |
| DeVos, C | 1 |
| Karppinen, A | 1 |
| Kautiainen, H | 1 |
| Petman, L | 1 |
| Burri, P | 1 |
| Reunala, T | 1 |
| Vincent, J | 1 |
| Liminana, R | 1 |
| Meredith, PA | 1 |
| Reid, JL | 1 |
1 review available for ebastine and Atopic Hypersensitivity
| Article | Year |
|---|---|
A preclinical overview of ebastine. Studies on the pharmacological properties of a novel histamine H1 receptor antagonist.
Topics: Animals; Butyrophenones; Drug Evaluation, Preclinical; Histamine H1 Antagonists; Humans; Hypersensit | 1996 |
5 trials available for ebastine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Itraconazole and rifampin alter significantly the disposition and antihistamine effect of ebastine and its metabolites in healthy participants.
Topics: Adult; Antifungal Agents; Butyrophenones; Cross-Over Studies; Drug Interactions; Enzyme Inhibitors; | 2010 |
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Hist | 2002 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamin | 1999 |
Comparison of cetirizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy.
Topics: Adult; Animals; Butyrophenones; Cetirizine; Conscious Sedation; Cross-Over Studies; Culicidae; Doubl | 2002 |
The pharmacokinetics, antihistamine and concentration-effect relationship of ebastine in healthy subjects.
Topics: Adult; Butyrophenones; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersens | 1988 |