Page last updated: 2024-09-03

e 64 and Malaria

e 64 has been researched along with Malaria in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Domínguez, JN; Gamboa de Domínguez, N; Gut, J; León, C; Rodrigues, J; Rosenthal, PJ1
Che, P; Cong, X; Huang, H; Huang, J; Jiang, H; Li, H; Li, X; Liu, X; Lu, W; Ma, H; Ma, R; Shen, X; Zhang, Y; Zhu, J1
Ayong, L; Bae, MA; Cechetto, J; Freitas-Junior, LH; Lee, E; Lee, HG; Lee, N; Lee, S; Lim, D; Liuzzi, M; Oh, S; Park, SB; Song, JS1
Amendola, G; Chouchene, K; Cosconati, S; Ettari, R; Grasso, S; Gut, J; Hellmich, UA; Krauth-Siegel, RL; Previti, S; Rosenthal, PJ; Schirmeister, T; Schmid, I; Ulrich, K; Wagner, A; Wich, PR; Zappalà, M1
Braga, SFP; Brandstetter, H; Caffrey, CR; Costa, FMR; da Silva, EB; de Andrade, SF; Ferreira, RS; Leite, PG; Machado, FS; Martins, LC; Oliveira, RB; Pereira, GAN; Ray, D; Soh, WT; Vieira, RP; Villela, FS1
Coppi, A; Hutter, C; Pinzon-Ortiz, C; Sinnis, P1
Aikawa, M; Leech, JH; McKerrow, JH; Nagasawa, H; Rosenthal, PJ1

Other Studies

7 other study(ies) available for e 64 and Malaria

ArticleYear
Synthesis and evaluation of new antimalarial phenylurenyl chalcone derivatives.
    Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

    Topics: Animals; Antimalarials; Chalcones; Cysteine Endopeptidases; Globins; Heme; Hemeproteins; Hydrolysis; Malaria; Mice; Phenylurea Compounds; Plasmodium berghei; Plasmodium falciparum; Polymers; Protease Inhibitors; Structure-Activity Relationship

2005
Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Animals; Antimalarials; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Malaria; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Weight; Plasmodium berghei; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2012
Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay.
    Journal of medicinal chemistry, 2014, Sep-11, Volume: 57, Issue:17

    Topics: Animals; Antimalarials; Area Under Curve; Cell Line, Tumor; Cell Survival; Drug Discovery; Drug Evaluation, Preclinical; Hep G2 Cells; Host-Parasite Interactions; Humans; Life Cycle Stages; Malaria; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Models, Chemical; Molecular Structure; Plasmodium chabaudi; Plasmodium falciparum; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2014
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).
    Journal of medicinal chemistry, 2017, 08-24, Volume: 60, Issue:16

    Topics: Antimalarials; Carbamates; Cathepsin L; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; HeLa Cells; Humans; Hydrogen Bonding; Malaria; Molecular Docking Simulation; Molecular Dynamics Simulation; Neglected Diseases; Phenylalanine; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2017
Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Animals; Cysteine Proteases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Schistosoma mansoni; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2019
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion.
    The Journal of experimental medicine, 2005, Jan-03, Volume: 201, Issue:1

    Topics: Amino Acid Sequence; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Immunoblotting; Immunoprecipitation; Leucine; Malaria; Molecular Sequence Data; Peptides; Plasmodium; Protozoan Proteins; Sporozoites; Virulence

2005
A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:5

    Topics: Animals; Cysteine Endopeptidases; Hemoglobins; Leucine; Leupeptins; Malaria; Microscopy, Electron; Molecular Weight; Plasmodium falciparum; Protease Inhibitors

1988