e 4031 has been researched along with Tachycardia, Ventricular in 7 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most common mechanism of sustained ventricular tachycardia (VT) is re-entry with an excitable gap, but the electrophysiologic properties and response to antiarrhythmic drugs in the area of slow conduction are not yet fully known." | 1.30 | Effects of class I and III antiarrhythmic drugs on ventricular tachycardia-interrupting critical paced cycle length with rapid pacing. ( Aizawa, Y; Naitoh, N; Takahashi, K; Washizuka, T, 1998) |
| "Six patients had sustained ventricular tachycardia (VT) and 5 had ventricular fibrillation (VF)." | 1.30 | Comparison of electrophysiologic effects of intravenous E-4031 and MS-551, novel class III antiarrhythmic agents, in patients with ventricular tachyarrhythmias. ( Aizawa, Y; Furushima, H; Naitoh, N; Tagawa, M; Taneda, K; Yamaura, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, L | 1 |
| Rajamani, S | 1 |
| Li, H | 1 |
| January, CT | 1 |
| Shryock, JC | 1 |
| Belardinelli, L | 1 |
| Izumi, D | 1 |
| Chinushi, M | 1 |
| Iijima, K | 1 |
| Ahara, S | 1 |
| Komura, S | 1 |
| Furushima, H | 2 |
| Hosaka, Y | 1 |
| Sanada, A | 1 |
| Yagihara, N | 1 |
| Aizawa, Y | 3 |
| Yamauchi, S | 2 |
| Yamaki, M | 2 |
| Watanabe, T | 2 |
| Yuuki, K | 1 |
| Kubota, I | 2 |
| Tomoike, H | 2 |
| Ogawa, S | 1 |
| Mitamura, H | 1 |
| Katoh, H | 1 |
| Naitoh, N | 2 |
| Washizuka, T | 1 |
| Takahashi, K | 1 |
| Tagawa, M | 1 |
| Yamaura, M | 1 |
| Taneda, K | 1 |
| Miyashita, T | 1 |
7 other studies available for e 4031 and Tachycardia, Ventricular
| Article | Year |
|---|---|
Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart.
Topics: 4-Aminopyridine; Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Barium Compounds; | 2009 |
Effects of bepridil versus E-4031 on transmural ventricular repolarization and inducibility of ventricular tachyarrhythmias in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Blood Pressure; Calcium Channel Blockers; Cerebral Revasc | 2010 |
Restitution properties and occurrence of ventricular arrhythmia in LQT2 type of long QT syndrome.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disease Models, Animal; Disease Suscept | 2002 |
Effect of E-4031, a new class III antiarrhythmic drug, on reentrant ventricular arrhythmias: comparison with conventional class I drugs.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disease Models, Animal; Disopyrami | 1993 |
Effects of class I and III antiarrhythmic drugs on ventricular tachycardia-interrupting critical paced cycle length with rapid pacing.
Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Child; Electrophysiology; Female; Heart | 1998 |
Comparison of electrophysiologic effects of intravenous E-4031 and MS-551, novel class III antiarrhythmic agents, in patients with ventricular tachyarrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1998 |
4-aminopyridine inhibits the occurrence of ventricular fibrillation but not ventricular tachycardia in the reperfused, P6olated rat heart.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Glyburide; Heart; Heart Rate; | 2000 |