e 4031 has been researched along with Cardiac Remodeling, Ventricular in 1 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arrhythmic outcome was defined as Torsade de Pointes (TdP) in the animal models and early afterdepolarizations (EADs) in the cell models." | 1.38 | Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes. ( Beekman, JD; de Boer, TP; Duker, G; Houtman, MJ; Jonsson, MK; Nalos, L; Peschar, M; Rook, MB; Sartipy, P; Thomsen, MB; van der Heyden, MA; van der Nagel, R; van Veen, TA; Varkevisser, R; Vos, MA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nalos, L | 1 |
| Varkevisser, R | 1 |
| Jonsson, MK | 1 |
| Houtman, MJ | 1 |
| Beekman, JD | 1 |
| van der Nagel, R | 1 |
| Thomsen, MB | 1 |
| Duker, G | 1 |
| Sartipy, P | 1 |
| de Boer, TP | 1 |
| Peschar, M | 1 |
| Rook, MB | 1 |
| van Veen, TA | 1 |
| van der Heyden, MA | 1 |
| Vos, MA | 1 |
1 other study available for e 4031 and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aza Compounds; Cell Line; Disease Models, Animal | 2012 |