e 4031 has been researched along with Bradycardia in 4 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Phenylephrine-induced reflex bradycardia increased QTbtb by 3 ms but decreased QTcB by 20 ms and QTcF by 12 ms." | 3.73 | Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition. ( Crimin, K; Fossa, AA; Gorczyca, W; Magnano, A; Raunig, DL; Winslow, R; Wisialowski, T; Wolfgang, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, L | 1 |
| Ma, J | 1 |
| Li, H | 1 |
| Wang, C | 1 |
| Grandi, E | 1 |
| Zhang, P | 1 |
| Luo, A | 1 |
| Bers, DM | 1 |
| Shryock, JC | 1 |
| Belardinelli, L | 1 |
| Fossa, AA | 1 |
| Wisialowski, T | 1 |
| Magnano, A | 1 |
| Wolfgang, E | 1 |
| Winslow, R | 1 |
| Gorczyca, W | 1 |
| Crimin, K | 1 |
| Raunig, DL | 1 |
| Hansen, RS | 1 |
| Olesen, SP | 1 |
| Grunnet, M | 1 |
| Imamura, H | 1 |
| Furukawa, Y | 1 |
| Kasama, M | 1 |
| Hoyano, Y | 1 |
| Yonezawa, T | 1 |
| Chiba, S | 1 |
4 other studies available for e 4031 and Bradycardia
| Article | Year |
|---|---|
Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Bradycardia; Disease Models, Anima | 2011 |
Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition.
Topics: Adrenergic beta-Agonists; Animals; Bradycardia; Dogs; ERG1 Potassium Channel; Ether-A-Go-Go Potassiu | 2005 |
Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Ether-A-Go-Go | 2007 |
Inhibition of delayed rectifier K+ current by dofetilide and E-4031 differentially affects electrical cardiac responses to vagus stimulation in anesthetized dogs.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Disease Models, Animal; Disopyramide; Dogs; Dose-Respo | 1998 |