Page last updated: 2024-10-26

e 4031 and Bradyarrhythmia

e 4031 has been researched along with Bradyarrhythmia in 4 studies

E 4031: class III anti-arrhythmia agent; structure given in UD

Research Excerpts

ExcerptRelevanceReference
" Phenylephrine-induced reflex bradycardia increased QTbtb by 3 ms but decreased QTcB by 20 ms and QTcF by 12 ms."3.73Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition. ( Crimin, K; Fossa, AA; Gorczyca, W; Magnano, A; Raunig, DL; Winslow, R; Wisialowski, T; Wolfgang, E, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, L1
Ma, J1
Li, H1
Wang, C1
Grandi, E1
Zhang, P1
Luo, A1
Bers, DM1
Shryock, JC1
Belardinelli, L1
Fossa, AA1
Wisialowski, T1
Magnano, A1
Wolfgang, E1
Winslow, R1
Gorczyca, W1
Crimin, K1
Raunig, DL1
Hansen, RS1
Olesen, SP1
Grunnet, M1
Imamura, H1
Furukawa, Y1
Kasama, M1
Hoyano, Y1
Yonezawa, T1
Chiba, S1

Other Studies

4 other studies available for e 4031 and Bradyarrhythmia

ArticleYear
Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
    Circulation, 2011, Apr-26, Volume: 123, Issue:16

    Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Bradycardia; Disease Models, Anima

2011
Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Bradycardia; Dogs; ERG1 Potassium Channel; Ether-A-Go-Go Potassiu

2005
Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Ether-A-Go-Go

2007
Inhibition of delayed rectifier K+ current by dofetilide and E-4031 differentially affects electrical cardiac responses to vagus stimulation in anesthetized dogs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Disease Models, Animal; Disopyramide; Dogs; Dose-Respo

1998