e 4031 has been researched along with Atrial Fibrillation in 7 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of E-4031, a new class III antiarrhythmic agent, on atrial fibrillation threshold (AFT), atrial effective refractory period (ERP), and interatrial conduction time (ACT) were investigated in Langendorff-perfused guinea pig hearts; the results were then compared with those of the class I agents disopyramide, procainamide, lidocaine, and flecainide." | 3.69 | Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs. ( Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T, 1994) |
| "Sotalol may inhibit IK." | 1.29 | Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms. ( Hara, Y; Masuda, Y; Mori, K; Nakaya, H; Saito, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ton, AT | 1 |
| Nguyen, W | 1 |
| Sweat, K | 1 |
| Miron, Y | 1 |
| Hernandez, E | 1 |
| Wong, T | 1 |
| Geft, V | 1 |
| Macias, A | 1 |
| Espinoza, A | 1 |
| Truong, K | 1 |
| Rasoul, L | 1 |
| Stafford, A | 1 |
| Cotta, T | 1 |
| Mai, C | 1 |
| Indersmitten, T | 1 |
| Page, G | 1 |
| Miller, PE | 1 |
| Ghetti, A | 1 |
| Abi-Gerges, N | 1 |
| Burashnikov, A | 1 |
| Belardinelli, L | 1 |
| Antzelevitch, C | 1 |
| Shiroshita-Takeshita, A | 1 |
| Mitamura, H | 1 |
| Sato, T | 1 |
| Shinagawa, K | 1 |
| Kurita, Y | 1 |
| Kanki, H | 1 |
| Takatsuki, S | 1 |
| Hara, M | 1 |
| Ogawa, S | 1 |
| Inoue, M | 1 |
| Inoue, D | 1 |
| Ishibashi, K | 1 |
| Sakai, R | 1 |
| Shirayama, T | 1 |
| Asayama, J | 1 |
| Nakagawa, M | 1 |
| Shimizu, A | 2 |
| Kaibara, M | 1 |
| Centurion, OA | 2 |
| Kapuku, G | 1 |
| Hirata, T | 1 |
| Fukatani, M | 2 |
| Yano, K | 2 |
| Hashiba, K | 1 |
| Mori, K | 1 |
| Hara, Y | 1 |
| Saito, T | 1 |
| Masuda, Y | 1 |
| Nakaya, H | 1 |
| Konoe, A | 1 |
| Isomoto, S | 1 |
7 other studies available for e 4031 and Atrial Fibrillation
| Article | Year |
|---|---|
Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart.
Topics: Adult; Atrial Fibrillation; Calcium; Cnidarian Venoms; ERG1 Potassium Channel; Heart Atria; Humans; | 2021 |
Inhibition of IKr potentiates development of atrial-selective INa block leading to effective suppression of atrial fibrillation.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Delayed Rectifier Potassium | 2015 |
Preserved effects of potassium channel blockers in the pacing-induced remodeled canine atrium: a comparison between E4031 and azimilide.
Topics: Animals; Atrial Fibrillation; Atrial Function; Cardiac Pacing, Artificial; Dogs; Electric Stimulatio | 2003 |
Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Disopyramide; | 1994 |
Electrophysiologic effects of a new class III antiarrhythmic agent, E-4031, on atrial flutter, atrial refractoriness, and conduction delay in a canine sterile pericarditis model.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dogs; Electric Stimulation; El | 1993 |
Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms.
Topics: Acetylcholine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutt | 1995 |
Electrophysiological effects of a new class III antiarrhythmic agent (E-4031) on the conduction and refractoriness of the in vivo human atrium.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Evaluation; Electrophysiology; Heart; Heart Atria; | 1993 |