e 4031 has been researched along with Anesthesia in 6 studies
E 4031: class III anti-arrhythmia agent; structure given in UD
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clobutinol has been clinically reported to induce long QT syndrome." | 1.35 | Clobutinol delays ventricular repolarization in the guinea pig heart: comparison with cardiac effects of HERG K+ channel inhibitor E-4031. ( Nakamura, M; Namekata, I; Sakurai, Y; Sasaki, R; Sendo, A; Takahara, A; Tanaka, H, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahara, A | 1 |
| Sasaki, R | 1 |
| Nakamura, M | 1 |
| Sendo, A | 1 |
| Sakurai, Y | 1 |
| Namekata, I | 1 |
| Tanaka, H | 1 |
| Yamazaki, K | 1 |
| Furukawa, Y | 2 |
| Kasama, M | 1 |
| Imamura, H | 1 |
| Chiba, S | 2 |
| Nagashima, Y | 1 |
| Hirose, M | 1 |
| Hoyano, Y | 1 |
| Lakhe, M | 1 |
| Spinelli, W | 1 |
| Parsons, RW | 1 |
| Colatsky, TJ | 1 |
| Lynch, JJ | 1 |
| Heaney, LA | 1 |
| Wallace, AA | 1 |
| Gehret, JR | 1 |
| Selnick, HG | 1 |
| Stein, RB | 1 |
| Sano, T | 1 |
| Sugiyama, S | 1 |
| Taki, K | 1 |
| Hanaki, Y | 1 |
| Shimada, Y | 1 |
| Ozawa, T | 1 |
6 other studies available for e 4031 and Anesthesia
| Article | Year |
|---|---|
Clobutinol delays ventricular repolarization in the guinea pig heart: comparison with cardiac effects of HERG K+ channel inhibitor E-4031.
Topics: Action Potentials; Amino Alcohols; Anesthesia; Animals; Antitussive Agents; Blood Pressure; Electric | 2009 |
Negative chronotropic and dromotropic effects of E-4031, an IKr blocker, on the atrioventricular node in anesthetized dog hearts.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Benzazepines; Cardiotonic Agents | 1996 |
Inhibition by E-4031 of the prolongation of the first returning cycle length after overdrive in anesthetized dog hearts.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Heart; Heart Rate; Pa | 1998 |
Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Benzimidazoles; Dogs; Electrocar | 1992 |
Suppression of lethal ischemic ventricular arrhythmias by the class III agent E4031 in a canine model of previous myocardial infarction.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Chloralose; Dogs; Electric Stimulation; | 1990 |
Effects of antiarrhythmic agents classified as class III group on ischaemia-induced myocardial damage in canine hearts.
Topics: Acetylglucosaminidase; Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Coro | 1990 |