dyphylline has been researched along with Asthma in 11 studies
Dyphylline: A THEOPHYLLINE derivative with broncho- and vasodilator properties. It is used in the treatment of asthma, cardiac dyspnea, and bronchitis.
dyphylline : An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the acute bronchodilator effect of increasing doses of intravenous theophylline and inhaled beta adrenergic agonists, we administered intravenous theophylline dissolved in ethylenediamine or proxyphylline and diprophylline or placebo in a double blind fashion to nine asthmatics on three different days." | 9.06 | Bronchodilator effect of theophylline preparations and aerosol fenoterol in stable asthma. ( Hartmann, V; Jörres, R; Magnussen, H, 1986) |
| "Dihydroxypropyl theophylline (dyphylline) was administered by aerosol in a single dose of 250 mg aerosolized over five minutes to two asthmatic volunteers and in a single dose of 375 mg aerosolized over ten minutes to two other asthmatic volunteers." | 7.66 | Dyphylline aerosol can induce bronchospasm in human asthmatics. ( Auer, S; Bardana, E; Brottem, J; Downes, H; Hirshman, C; Lawyer, C; Lynn, R, 1982) |
| "This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma." | 7.66 | Dyphylline aerosol attenuates antigen-induced bronchoconstriction in experimental canine asthma. ( Downes, H; Farbood, A; Gerber, N; Hirshman, CA; Lawyer, C; Rodgers, R, 1981) |
| "To compare the acute bronchodilator effect of increasing doses of intravenous theophylline and inhaled beta adrenergic agonists, we administered intravenous theophylline dissolved in ethylenediamine or proxyphylline and diprophylline or placebo in a double blind fashion to nine asthmatics on three different days." | 5.06 | Bronchodilator effect of theophylline preparations and aerosol fenoterol in stable asthma. ( Hartmann, V; Jörres, R; Magnussen, H, 1986) |
| "In study I, carried out on 9 asthmatics to investigate whether the bronchodilator and protective effect of intravenous theophylline, dissolved in ethylene diamine (T." | 5.06 | [Comparison of the bronchodilator and protective effect of methylxanthines]. ( Jörres, R; Litt, M; Magnussen, H; Reuss, G; Stutz, P, 1986) |
| "This study was a randomized double-blind evaluation of three doses of dyphylline, theophylline, and placebo for blocking exercise-induced bronchospasm (EIB)." | 5.05 | Dyphylline versus theophylline: a double-blind comparative evaluation. ( Bierman, CW; Furukawa, CT; Pierson, WE; Shapiro, GG, 1983) |
| "Dihydroxypropyl theophylline (dyphylline) was administered by aerosol in a single dose of 250 mg aerosolized over five minutes to two asthmatic volunteers and in a single dose of 375 mg aerosolized over ten minutes to two other asthmatic volunteers." | 3.66 | Dyphylline aerosol can induce bronchospasm in human asthmatics. ( Auer, S; Bardana, E; Brottem, J; Downes, H; Hirshman, C; Lawyer, C; Lynn, R, 1982) |
| "This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma." | 3.66 | Dyphylline aerosol attenuates antigen-induced bronchoconstriction in experimental canine asthma. ( Downes, H; Farbood, A; Gerber, N; Hirshman, CA; Lawyer, C; Rodgers, R, 1981) |
| "The pharmacokinetics and urinary excretion of intravenously administered 7-(2,3-dihydroxypropyl) theophylline (dyphylline), were studied in a 37-yr-old asthmatic woman with ethylene diamine sensitivity who manifested intolerance to intravenous aminophylline on three separate occasions." | 3.66 | Utilization of intravenous dihydroxypropyl theophylline (dyphylline) in an aminophylline-sensitive patient, and its pharmacokinetic comparison with theophylline. ( Bardana, EJ; Gerber, N; Lawyer, CH; Rodgers, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loytved, G | 1 |
| Werdermann, K | 1 |
| Jorde, W | 1 |
| Petro, W | 1 |
| Furukawa, CT | 1 |
| Shapiro, GG | 1 |
| Pierson, WE | 1 |
| Bierman, CW | 1 |
| Lawyer, C | 2 |
| Auer, S | 1 |
| Brottem, J | 1 |
| Bardana, E | 1 |
| Hirshman, C | 1 |
| Lynn, R | 1 |
| Downes, H | 2 |
| Hirshman, CA | 1 |
| Farbood, A | 1 |
| Rodgers, R | 2 |
| Gerber, N | 2 |
| Ufkes, JG | 1 |
| Leeuwin, RS | 1 |
| Ottenhof, M | 1 |
| Zeegers, A | 1 |
| Zuidema, J | 1 |
| Lawyer, CH | 1 |
| Bardana, EJ | 1 |
| Valia, KH | 1 |
| Hartman, CA | 1 |
| Kucharczyk, N | 1 |
| Sofia, RD | 1 |
| Magnussen, H | 2 |
| Jörres, R | 2 |
| Hartmann, V | 1 |
| Litt, M | 1 |
| Reuss, G | 1 |
| Stutz, P | 1 |
| Cushley, MJ | 1 |
| Holgate, ST | 1 |
| Wrońska, J | 1 |
| Droszcz, W | 1 |
5 trials available for dyphylline and Asthma
| Article | Year |
|---|---|
Clinical efficiency of neobiphyllineR-studies on lung function and serum levels after rectal application of a combination of methyl-xanthines.
Topics: Adult; Aged; Airway Resistance; Aminophylline; Asthma; Clinical Trials as Topic; Drug Combinations; | 1983 |
Dyphylline versus theophylline: a double-blind comparative evaluation.
Topics: Adolescent; Asthma; Bronchial Spasm; Child; Double-Blind Method; Dyphylline; Female; Forced Expirato | 1983 |
Bronchodilator effect of theophylline preparations and aerosol fenoterol in stable asthma.
Topics: Airway Resistance; Aminophylline; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Synerg | 1986 |
[Comparison of the bronchodilator and protective effect of methylxanthines].
Topics: Adolescent; Adult; Aminophylline; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Dose-Resp | 1986 |
Bronchodilator actions of xanthine derivatives administered by inhalation in asthma.
Topics: Adult; Aerosols; Aged; Airway Resistance; Aminophylline; Asthma; Bronchi; Dyphylline; Female; Forced | 1985 |
6 other studies available for dyphylline and Asthma
| Article | Year |
|---|---|
Dyphylline aerosol can induce bronchospasm in human asthmatics.
Topics: Adult; Aerosols; Aged; Asthma; Bronchial Spasm; Bronchodilator Agents; Dyphylline; Female; Forced Ex | 1982 |
Dyphylline aerosol attenuates antigen-induced bronchoconstriction in experimental canine asthma.
Topics: Aerosols; Animals; Antigens; Ascaris; Asthma; Bronchial Diseases; Constriction, Pathologic; Dogs; Dy | 1981 |
Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pig.
Topics: Aminophylline; Animals; Asthma; Dyphylline; Female; Guinea Pigs; In Vitro Techniques; Theophylline; | 1981 |
Utilization of intravenous dihydroxypropyl theophylline (dyphylline) in an aminophylline-sensitive patient, and its pharmacokinetic comparison with theophylline.
Topics: Adult; Aminophylline; Asthma; Dyphylline; Female; Humans; Injections, Intravenous; Kinetics; Theophy | 1980 |
Simultaneous determination of dyphylline and theophylline in human plasma by high-performance liquid chromatography.
Topics: Asthma; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Reference Values; Theobr | 1980 |
[Theophylline and its derivatives].
Topics: Aminophylline; Asthma; Bronchi; Bronchial Spasm; Drug Evaluation; Drug Interactions; Dyphylline; Hum | 1985 |