dyclonine has been researched along with Parkinson Disease in 1 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dyclonine which was found to have antioxidant activity and would benefit patients with Friedreich's ataxia, is a commonly used local anesthetic." | 1.91 | Dyclonine relieves the Parkinson's disease progression in rotenone-induced Drosophila model. ( Guo, J; Li, M; Li, Y; Ling, L; Liu, F; Luo, S; Ma, B; Wang, H, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 1 |
| Luo, S | 1 |
| Li, Y | 2 |
| Ma, B | 1 |
| Liu, F | 1 |
| Wang, H | 1 |
| Guo, J | 1 |
| Ling, L | 1 |
1 other study available for dyclonine and Parkinson Disease
| Article | Year |
|---|---|
Dyclonine relieves the Parkinson's disease progression in rotenone-induced Drosophila model.
Topics: Animals; Disease Progression; Dopaminergic Neurons; Drosophila; Neuroprotective Agents; NF-E2-Relate | 2023 |