dup-721 and Bacterial-Infections

dup-721 has been researched along with Bacterial-Infections* in 1 studies

Other Studies

1 other study(ies) available for dup-721 and Bacterial-Infections

Article	Year
Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones. Bioorganic & medicinal chemistry letters, 1998, May-19, Volume: 8, Issue:10 A series of conformationally restricted, [6,5,5] and [6,6,5] tricyclic fused oxazolidinones were synthesized and tested for antibacterial activity. Several compounds in the trans-[6,5,5] series demonstrated potent in vitro and in vivo activity. This work provides valuable information regarding the preferred conformational orientation of the oxazolidinones at the binding site. Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Indicators and Reagents; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazoles; Structure-Activity Relationship	1998

Article

Year

Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones.

Bioorganic & medicinal chemistry letters, 1998, May-19, Volume: 8, Issue:10

A series of conformationally restricted, [6,5,5] and [6,6,5] tricyclic fused oxazolidinones were synthesized and tested for antibacterial activity. Several compounds in the trans-[6,5,5] series demonstrated potent in vitro and in vivo activity. This work provides valuable information regarding the preferred conformational orientation of the oxazolidinones at the binding site.

Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Indicators and Reagents; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazoles; Structure-Activity Relationship

1998