Compounds > duocarmycin sa
Page last updated: 2024-09-03

duocarmycin sa and Leukemia L 1210

duocarmycin sa has been researched along with Leukemia L 1210 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boger, DL; Jin, Q; Searcey, M; Tse, WC1
Boger, DL; Broward, MA; Dunwiddie, I; Lajiness, JP; Robertson, WM; Vielhauer, GA; Weir, SJ1
Boger, DL; Brown, D; Duncan, KK; Parelkar, NK; Vielhauer, GA; Wolfe, AL1
Boger, DL; Hedrick, MP; Hughes, TV1
Boger, DL; Brunette, SR; Garbaccio, RM1
Boger, DL; Ellis, DA; Wolkenberg, SE1
Searcey, M1

Reviews

1 review(s) available for duocarmycin sa and Leukemia L 1210

ArticleYear
Duocarmycins--natures prodrugs?
    Current pharmaceutical design, 2002, Volume: 8, Issue:15

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Survival; DNA; Drug Stability; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Prodrugs; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Tumor Cells, Cultured

2002

Other Studies

6 other study(ies) available for duocarmycin sa and Leukemia L 1210

ArticleYear
Bifunctional alkylating agents derived from duocarmycin SA: potent antitumor activity with altered sequence selectivity.
    Bioorganic & medicinal chemistry letters, 2000, Mar-06, Volume: 10, Issue:5

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Catalysis; DNA; Duocarmycins; Indoles; Leukemia L1210; Pyrroles; Stereoisomerism

2000
Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation.
    Journal of medicinal chemistry, 2010, Nov-11, Volume: 53, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Drug Screening Assays, Antitumor; Duocarmycins; Indoles; Leukemia L1210; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Phenols; Prodrugs; Pyrroles; Stereoisomerism; Structure-Activity Relationship

2010
Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs.
    Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10

    Topics: Alkylation; Animals; Antibiotics, Antineoplastic; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; DNA; Duocarmycins; Indicators and Reagents; Indoles; Leukemia L1210; Mice; Prodrugs; Pyrrolidinones; Spectrophotometry, Ultraviolet; Stereoisomerism; Xenograft Model Antitumor Assays

2013
Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa.
    The Journal of organic chemistry, 2001, Apr-06, Volume: 66, Issue:7

    Topics: Alkylation; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Crystallography, X-Ray; DNA; Duocarmycins; Indoles; Inhibitory Concentration 50; Kinetics; Leucomycins; Leukemia L1210; Mice; Pyrroles; Pyrrolidinones

2001
Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins.
    The Journal of organic chemistry, 2001, Jul-27, Volume: 66, Issue:15

    Topics: Alkylation; Animals; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Duocarmycins; Humans; Indoles; Leucomycins; Leukemia L1210; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyrroles; Pyrrolidinones; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet

2001
Metal cation complexation and activation of reversed CPyI analogues of CC-1065 and duocarmycin SA: partitioning the effects of binding and catalysis.
    Journal of the American Chemical Society, 2001, Sep-26, Volume: 123, Issue:38

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Catalysis; DNA; Duocarmycins; Indoles; Kinetics; Leucomycins; Leukemia L1210; Pyrroles; Quinolones; Stereoisomerism

2001