Page last updated: 2024-08-24

duloxetine hydrochloride and Pain, Chronic

duloxetine hydrochloride has been researched along with Pain, Chronic in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's44 (64.71)24.3611
2020's24 (35.29)2.80

Authors

AuthorsStudies
Bierma-Zeinstra, SMA; Bindels, PJE; Koffeman, AR; Koopmanschap, MA; Schiphof, D; van den Driest, JJ1
Blikman, T; Bulstra, SK; Dijkstra, B; Rienstra, W; Stevens, M; Ten Hagen, AJ; van den Akker-Scheek, I; van Raaij, TM; Zijlstra, WP1
Ammitzbøll, N; Arendt-Nielsen, L; Bertoli, D; Brock, C; Drewes, AM; Olesen, AE; Petersen, KK1
Clark, JD; Irvine, KA; Sahbaie, P; Shi, XY1
Koyama, K1
Alcántara Montero, A; Pacheco de Vasconcelos, SR1
Beaudoin, FL; DeLomba, WC; Gaither, R; McLean, SA1
Banner, E; Brummett, CM; Clauw, DJ; Cole, C; Favorite, T; Fisher, L; Golmirzaie, GM; Harris, RE; Harte, SE; Hassett, AL; Ichesco, E; Kaplan, CM; Kidwell, KM; King, A; Kohns, DJ; Kratz, AL; Lobo, R; Mawla, I; McAfee, J; Murphy, SL; Schneiderhan, JR; Schrepf, A; Scott, KA; Shaikh, S; Tsodikov, A; Wasserman, RA; Williams, DA1
Dang, L; Vandal, C; Winslow, BT1
Nodera, H1
Chung, CP; Corriere, MA; Daniel, LL; Dickson, AL; Dupont, WD; Hall, K; Murray, KT; Nepal, P; Plummer, WD; Ray, WA; Stein, CM1
Birkinshaw, H; Cole, P; Eccleston, C; Friedrich, CM; Moore, RA; Phillippo, D; Pincus, T; Serfaty, M; Stewart, G; White, S1
Guo, Y; Li, G; Ma, X; Sun, J; Sun, W; Wang, L; Zhou, S1
Chen, H; He, Y; Li, J; Li, L; Su, H; Su, S; Wang, T; Yang, P1
Flynn, D1
Alev, L; Cheng, YY; Enomoto, H; Fujikoshi, S; Skljarevski, V; Wang, J; Yue, L1
Ariyoshi, K; Hasegawa, Y; Hasuo, H; Ishiki, H; Iwase, S; Kataoka, Y; Kawaguchi, T; Koyama, A; Matsuda, Y; Matsumoto, Y; Matsuoka, H; Miyaji, T; Morita, T; Nakura, M; Ohtake, Y; Otani, H; Otsuka, M; Oyamada, S; Sakai, K; Sakuma, H; Satomi, E; Tahara, K; Tokoro, A; Tsukuura, H; Yamaguchi, T1
Liu, Z; Lu, W; Wang, Q; Weng, C; Xu, J1
Asaki, T; Fujita, M; Kasai, E; Matsuo, M; Sakurai, Y; Tamano, R; Yoneda, S1
Clark, JD; Ferguson, AR; Irvine, KA; Sahbaie, P1
Kimura, M; Onda, A1
Badgaiyan, RD; Gupta, K; Jarrett, S; Palzer, EF; Sagi, V; Tran, H1
Ishida, M; Itoh, N; Konno, S; Ochiai, T; Tsuji, T; Uchio, Y1
Navratilova, E; Phelps, CE; Porreca, F1
Auer, DP; Bailey, H; Cottam, WJ; Knaggs, RD; Mahajan, RP; Reckziegel, D; Tench, CR; Walsh, DA1
Bierma-Zeinstra, SMA; Bindels, PJE; Koffeman, AR; Koopmanschap, MA; Luijsterburg, PAJ; Schiphof, D; van den Driest, JJ1
Murai, N; Naito, M; Nakano, T; Ohmichi, M; Ohmichi, Y; Oshibuchi, H; Sato, J; Takeshita, N; Yasui, M1
DiMarzio, M; Gillogly, M; Pilitsis, JG; Prabhala, T; Prusik, J; Sabourin, S1
Enomoto, T; Hasegawa, R; Hori, N; Inada, E; Isek, M; Katsuta, Y; Koh, K; Saito, R; Sugasawa, Y; Sugita, M; Takahashi, Y; Yamaguchi, K1
Beaudoin, FL; McLean, SA; Santhanam, DR; Strauss, DH1
Alev, L; Enomoto, H; Konno, SI; Ochiai, T; Oda, N1
Bidari, A; Ghavidel-Parsa, B; Hassankhani, A; Hosseini, S; Moazen-Zadeh, E; Rahmani, S1
Bi, L; Chen, J; Dueñas, H; He, D; Li, X; Li, Z; Skljarevski, V; Wang, CN; Wang, G; Wu, T; Yue, L; Zhao, D1
Alaka, K; Arnold, LM; Mehta, R; Qiao, M; Upadhyaya, HP; Williams, D1
Buhidma, Y; Duty, S; Leta, V; Malcangio, M; Ray Chaudhuri, K; Rukavina, K; Sportelli, C1
Gaynor, PJ; Liu, P; Weller, MA; Wohlreich, MM1
Andrews, JS; Bansal, M; Happich, M; Klein, RW; Wielage, RC1
Cawston, H; Davie, A; Happich, M; Paget, MA; Skljarevski, V1
Beekman, AT; Bet, PM; de Heer, EW; Dekker, J; Hakkaart-Van Roijen, L; Holwerda, TJ; Kat, F; Ringoir, L; Roth, J; van der Feltz-Cornelis, CM; van Eck van der Sluijs, JF; van Marwijk, HW1
Cai, N; Moore, RA; Skljarevski, V; Tölle, TR1
Itoh, M; Masuda, R; Suzuki, T1
Bhatnagar, A; Billeter, AT; Hellmann, JL; Polk, HC1
Hughes, RA; Lunn, MP; Wiffen, PJ1
Ahl, J; Margherita, A; Ruff, DD; Sagman, D; Schroer, M; Williamson, OD; Wohlreich, MM1
Engel, CC1
Breivik, H1
Aoki, T; Fushiki, H; Honda, S; Irie, M; Iwashita, A; Murai, N; Murakami, Y; Nagakura, Y; Tamura, S1
Asaki, T; Hasegawa, M; Ishida, M; Shinohara, S; Tamano, R1
Bhatia, A1
Taylor, BK; Westlund, KN1
Alev, L; Konno, S; Ochiai, T; Oda, N1
Bi, L; Chen, J; Dueñas, H; He, D; Li, X; Li, Z; Skljarevski, V; Wang, CN; Wang, G; Yue, L; Zhao, D1
Alvarenga, R; Manhães, A; Schmidt, G; Schmidt, S1
Cutler, N1
Alcantara-Montero, A1
Dong, D; Ji, Z; Li, H; Yan, S; Zhang, M1
Granger, RE; Hussain, N; Lee, AC; Lee, MS; Li, H; McIntosh, D; Raskin, J; Ruschel, S; Sagman, D1
Banerjee, M; Griggs, JJ; Hayes, DF; Henry, NL; Schott, AF; Smerage, JB; Van Poznak, C; Wicha, M1
Liu, J; Shi, L; Zhao, Y1
Patel, TA; Rastogi, R; Swarm, RA1
Hegerl, U; Hundemer, HP; Linden, M; Mergl, R; Quail, D; Schneider, E1
Dundon, K; Mease, PJ; Sarzi-Puttini, P1
Rizzi, M; Sarzi-Puttini, P; Spaeth, M1
Gaynor, P; Hanna, S; Hochberg, MC; Risser, R; Wohlreich, M1
Citrome, L; Weiss-Citrome, A2
Langley, P; Nalamachu, S; Pergolizzi, JV; Raffa, RB; Rodriguez, G; Taylor, R1
Gordin, VN; Lamberg, JJ1

Reviews

16 review(s) available for duloxetine hydrochloride and Pain, Chronic

ArticleYear
Role of vortioxetine in the treatment of neuropathic pain.
    Revista espanola de anestesiologia y reanimacion, 2022, Volume: 69, Issue:10

    Topics: Antidepressive Agents; Chronic Pain; Duloxetine Hydrochloride; Humans; Neuralgia; Vortioxetine

2022
Antidepressants for pain management in adults with chronic pain: a network meta-analysis.
    The Cochrane database of systematic reviews, 2023, 05-10, Volume: 5

    Topics: Adult; Antidepressive Agents; Chronic Pain; Duloxetine Hydrochloride; Humans; Milnacipran; Network Meta-Analysis; Pain Management; Randomized Controlled Trials as Topic

2023
Efficacy and safety of duloxetine in chronic musculoskeletal pain: a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2023, May-18, Volume: 24, Issue:1

    Topics: Analgesics; Antidepressive Agents; Chronic Pain; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain

2023
Efficacy and safety of duloxetine in osteoarthritis or chronic low back pain: a Systematic review and meta-analysis.
    Osteoarthritis and cartilage, 2020, Volume: 28, Issue:6

    Topics: Analgesics; Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Osteoarthritis; Treatment Outcome

2020
Pain in Parkinson's disease: new concepts in pathogenesis and treatment.
    Current opinion in neurology, 2019, Volume: 32, Issue:4

    Topics: Analgesics; Botulinum Toxins; Chronic Pain; Deep Brain Stimulation; Duloxetine Hydrochloride; Humans; Naloxone; Oxycodone; Pain Management; Parkinson Disease

2019
Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9

    Topics: Administration, Oral; Analgesics; Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Randomized Controlled Trials as Topic; Thiophenes

2013
Transient receptor potential ion channels: powerful regulators of cell function.
    Annals of surgery, 2014, Volume: 259, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2014
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.
    The Cochrane database of systematic reviews, 2014, Jan-03, Issue:1

    Topics: Adult; Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Randomized Controlled Trials as Topic; Thiophenes

2014
The noradrenergic locus coeruleus as a chronic pain generator.
    Journal of neuroscience research, 2017, Volume: 95, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Pain; Duloxetine Hydrochloride; Humans; Locus Coeruleus; Norepinephrine; Serotonin and Noradrenaline Reuptake Inhibitors

2017
[Desvenlafaxine and neuropathic pain: additional clinical benefits of a second generation serotonin-noradrenaline reuptake inhibitor].
    Revista de neurologia, 2017, Mar-01, Volume: 64, Issue:5

    Topics: Antidepressive Agents; Biological Availability; Biotransformation; Chronic Pain; Clinical Trials as Topic; Cytochrome P-450 Enzyme System; Depressive Disorder; Desvenlafaxine Succinate; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Neuralgia; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2017
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Desipramine; Drug Interactions; Duloxetine Hydrochloride; Fentanyl; Humans; Male; Methadone; Middle Aged; Oxycodone; Polypharmacy; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Sulfonamides; Thiophenes; Transdermal Patch

2011
Pharmacotherapy of fibromyalgia.
    Best practice & research. Clinical rheumatology, 2011, Volume: 25, Issue:2

    Topics: Analgesics; Chronic Pain; Clinical Trials as Topic; Cognition Disorders; Cyclopropanes; Duloxetine Hydrochloride; Fatigue; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Mood Disorders; Pain Management; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sleep Wake Disorders; Syndrome; Thiophenes; Treatment Outcome

2011
Fibromyalgia and sleep.
    Best practice & research. Clinical rheumatology, 2011, Volume: 25, Issue:2

    Topics: Analgesics; Central Nervous System Sensitization; Chronic Pain; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Physical Therapy Modalities; Polysomnography; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Wake Disorders; Syndrome; Thiophenes

2011
Clinically relevant outcomes based on analysis of pooled data from 2 trials of duloxetine in patients with knee osteoarthritis.
    The Journal of rheumatology, 2012, Volume: 39, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Aged; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2012
A systematic review of duloxetine for osteoarthritic pain: what is the number needed to treat, number needed to harm, and likelihood to be helped or harmed?
    Postgraduate medicine, 2012, Volume: 124, Issue:1

    Topics: Chronic Pain; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain; Osteoarthritis; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes

2012
A review of duloxetine 60 mg once-daily dosing for the management of diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain due to chronic osteoarthritis pain and low back pain.
    Pain practice : the official journal of World Institute of Pain, 2013, Volume: 13, Issue:3

    Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Low Back Pain; Musculoskeletal Pain; Osteoarthritis; Thiophenes

2013

Trials

23 trial(s) available for duloxetine hydrochloride and Pain, Chronic

ArticleYear
No Added Value of Duloxetine in Patients With Chronic Pain due to Hip or Knee Osteoarthritis: A Cluster-Randomized Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2022, Volume: 74, Issue:5

    Topics: Chronic Pain; Duloxetine Hydrochloride; Humans; Knee Joint; Osteoarthritis, Hip; Osteoarthritis, Knee; Treatment Outcome

2022
Duloxetine in OsteoArthritis (DOA) study: effects of duloxetine on pain and function in end-stage hip and knee OA - a pragmatic enriched randomized controlled trial.
    BMC musculoskeletal disorders, 2022, Feb-05, Volume: 23, Issue:1

    Topics: Chronic Pain; Duloxetine Hydrochloride; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Treatment Outcome

2022
The effect of duloxetine on mechanistic pain profiles, cognitive factors and clinical pain in patients with painful knee osteoarthritis-A randomized, double-blind, placebo-controlled, crossover study.
    European journal of pain (London, England), 2022, Volume: 26, Issue:8

    Topics: Analgesics; Chronic Pain; Cognition; Cross-Over Studies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Osteoarthritis, Knee; Treatment Outcome

2022
An Interventional Response Phenotyping Study in Chronic Low Back Pain: Protocol for a Mechanistic Randomized Controlled Trial.
    Pain medicine (Malden, Mass.), 2023, 08-04, Volume: 24, Issue:Suppl 1

    Topics: Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Physical Therapy Modalities; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome

2023
The Clinical Relevance of Pain Severity Changes: Is There Any Difference Between Asian and Caucasian Patients With Osteoarthritis Pain?
    Pain practice : the official journal of World Institute of Pain, 2020, Volume: 20, Issue:2

    Topics: Adult; Aged; Analgesics; Asian People; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain Measurement; Severity of Illness Index; Treatment Outcome; White People

2020
Predictors of duloxetine response in patients with neuropathic cancer pain: a secondary analysis of a randomized controlled trial-JORTC-PAL08 (DIRECT) study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:6

    Topics: Adult; Aged; Cancer Pain; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Japan; Male; Middle Aged; Neoplasms; Neuralgia; Pain Measurement; Placebos; Prognosis; Treatment Outcome

2020
Efficacy of duloxetine in patients with knee osteoarthritis or chronic low back pain with early pain reduction: An exploratory post-hoc analysis of Japanese phase 3, 1-year extension studies.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2022, Volume: 27, Issue:3

    Topics: Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Humans; Japan; Low Back Pain; Osteoarthritis, Knee; Pain Measurement; Quality of Life; Treatment Outcome

2022
Imaging pain relief in osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome.
    BMJ open, 2017, 06-26, Volume: 7, Issue:6

    Topics: Adult; Aged; Brain; Chronic Pain; Cross-Over Studies; Double-Blind Method; Duloxetine Hydrochloride; Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteoarthritis, Knee; Pain Management; Pain Measurement; Quality of Life; Research Design; Surveys and Questionnaires; Treatment Outcome; United Kingdom

2017
Effectiveness and cost-effectiveness of duloxetine added to usual care for patients with chronic pain due to hip or knee osteoarthritis: protocol of a pragmatic open-label cluster randomised trial (the DUO trial).
    BMJ open, 2017, Sep-11, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Chronic Pain; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Hip; Hip Joint; Humans; Joints; Knee; Knee Joint; Male; Musculoskeletal Pain; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Management; Quality of Life; Research Design; Treatment Outcome

2017
Study protocol for a randomised, double-blind, placebo-controlled clinical trial of duloxetine for the treatment and prevention of musculoskeletal pain: altering the transition from acute to chronic pain (ATTAC pain).
    BMJ open, 2019, 03-05, Volume: 9, Issue:3

    Topics: Acute Pain; Adult; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Musculoskeletal Pain; Pain Management; Pain Measurement; Serotonin and Noradrenaline Reuptake Inhibitors; Treatment Outcome

2019
An Open-Label, 52-Week, Phase III Trial of Duloxetine in Japanese Patients with Chronic Low Back Pain.
    Pain medicine (Malden, Mass.), 2019, 08-01, Volume: 20, Issue:8

    Topics: Adult; Aged; Analgesics; Chronic Pain; Constipation; Duloxetine Hydrochloride; Female; Humans; Japan; Low Back Pain; Male; Middle Aged; Nausea; Pain Measurement; Sleepiness; Triethylenemelamine; Xerostomia

2019
Comparing duloxetine and pregabalin for treatment of pain and depression in women with fibromyalgia: an open-label randomized clinical trial.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2019, Volume: 27, Issue:1

    Topics: Adult; Chronic Pain; Depression; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Medication Adherence; Middle Aged; Pregabalin; Treatment Outcome; Young Adult

2019
Maintenance of effect of duloxetine in Chinese patients with pain due to osteoarthritis: 13-week open-label extension data.
    BMC musculoskeletal disorders, 2019, Apr-22, Volume: 20, Issue:1

    Topics: Aged; Analgesics; Arthralgia; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome

2019
Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial.
    Pediatric rheumatology online journal, 2019, May-28, Volume: 17, Issue:1

    Topics: Adolescent; Analgesics; Analysis of Variance; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Pain Measurement; Prospective Studies; Serotonin and Noradrenaline Reuptake Inhibitors

2019
Comparison of safety outcomes among Caucasian, Hispanic, Black, and Asian patients in duloxetine studies of chronic painful conditions.
    Current medical research and opinion, 2013, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Analgesics; Asian; Black or African American; Chronic Pain; Duloxetine Hydrochloride; Female; Hispanic or Latino; Humans; Male; Middle Aged; Thiophenes; White People

2013
Effectiveness and cost-effectiveness of transmural collaborative care with consultation letter (TCCCL) and duloxetine for major depressive disorder (MDD) and (sub)chronic pain in collaboration with primary care: design of a randomized placebo-controlled m
    BMC psychiatry, 2013, May-24, Volume: 13

    Topics: Adaptation, Psychological; Antidepressive Agents; Chronic Pain; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Patient Care Team; Primary Health Care; Quality of Life; Referral and Consultation; Research Design; Self Care; Thiophenes

2013
Duloxetine use in chronic painful conditions--individual patient data responder analysis.
    European journal of pain (London, England), 2014, Volume: 18, Issue:1

    Topics: Antidepressive Agents; Chronic Pain; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Fibromyalgia; Humans; Individuality; Low Back Pain; Osteoarthritis; Pain Measurement; Thiophenes; Treatment Outcome

2014
Onset of response with duloxetine treatment in patients with osteoarthritis knee pain and chronic low back pain: a post hoc analysis of placebo-controlled trials.
    Clinical therapeutics, 2014, Apr-01, Volume: 36, Issue:4

    Topics: Analgesics; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Male; Osteoarthritis, Knee; Pain Measurement

2014
Randomized, Double-blind, Placebo-controlled Phase III Trial of Duloxetine Monotherapy in Japanese Patients With Chronic Low Back Pain.
    Spine, 2016, Nov-15, Volume: 41, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Japan; Low Back Pain; Male; Middle Aged; Pain Measurement; Placebos; Time Factors; Treatment Outcome; Young Adult

2016
Efficacy and safety of duloxetine in Chinese patients with chronic pain due to osteoarthritis: a randomized, double-blind, placebo-controlled study.
    Osteoarthritis and cartilage, 2017, Volume: 25, Issue:6

    Topics: Aged; Analgesics; Asian People; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Treatment Outcome

2017
Clinical study of duloxetine hydrochloride combined with doxazosin for the treatment of pain disorder in chronic prostatitis/chronic pelvic pain syndrome: An observational study.
    Medicine, 2017, Volume: 96, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Chronic Pain; Doxazosin; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Pelvic Pain; Prospective Studies; Prostatitis; Serotonin and Noradrenaline Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Syndrome; Young Adult

2017
Attributes of response in depressed patients switched to treatment with duloxetine.
    International journal of clinical practice, 2011, Volume: 65, Issue:1

    Topics: Adult; Affective Symptoms; Antidepressive Agents; Chronic Pain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2011
Pilot study of duloxetine for treatment of aromatase inhibitor-associated musculoskeletal symptoms.
    Cancer, 2011, Dec-15, Volume: 117, Issue:24

    Topics: Adult; Aged; Aromatase Inhibitors; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Musculoskeletal Diseases; Pain; Pilot Projects; Postmenopause; Selective Serotonin Reuptake Inhibitors; Thiophenes

2011

Other Studies

29 other study(ies) available for duloxetine hydrochloride and Pain, Chronic

ArticleYear
Monoamine control of descending pain modulation after mild traumatic brain injury.
    Scientific reports, 2022, 09-29, Volume: 12, Issue:1

    Topics: Amines; Animals; Brain Concussion; Brain Injuries, Traumatic; Chronic Pain; Duloxetine Hydrochloride; Female; Male; Mice; Norepinephrine; Ondansetron; Reboxetine; Receptors, Adrenergic; Selective Serotonin Reuptake Inhibitors; Serotonin

2022
Comparison of efficacy and safety in the combination therapies of duloxetine and S-flurbiprofen plaster, and of duloxetine and conventional NSAIDs for chronic pain in patients with osteoarthritis (OASIS DUAL study).
    Drug discoveries & therapeutics, 2022, Nov-20, Volume: 16, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Flurbiprofen; Humans; Male; Osteoarthritis; Treatment Outcome

2022
Tolerability and efficacy of duloxetine for the prevention of persistent musculoskeletal pain after trauma and injury: a pilot three-group randomized controlled trial.
    Pain, 2023, 04-01, Volume: 164, Issue:4

    Topics: Acute Pain; Adult; Chronic Pain; Double-Blind Method; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain; Randomized Controlled Trials as Topic; Treatment Outcome

2023
Fibromyalgia: Diagnosis and Management.
    American family physician, 2023, Volume: 107, Issue:2

    Topics: Analgesics; Chronic Pain; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Pregabalin

2023
[Medical Treatment of Chronic Pain].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:3

    Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; Humans; Pregabalin

2023
Duloxetine, Gabapentin, and the Risk for Acute Myocardial Infarction, Stroke, and Out-of-Hospital Death in Medicare Beneficiaries With Non-Cancer Pain.
    The Clinical journal of pain, 2023, 05-01, Volume: 39, Issue:5

    Topics: Aged; Chronic Pain; Duloxetine Hydrochloride; Gabapentin; Hospitals; Humans; Medicare; Myocardial Infarction; Retrospective Studies; Stroke; United States

2023
Electroacupuncture attenuates chronic inflammatory pain and depression comorbidity by inhibiting hippocampal neuronal apoptosis via the PI3K/Akt signaling pathway.
    Neuroscience letters, 2023, 08-24, Volume: 812

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Chronic Pain; Comorbidity; Depression; Duloxetine Hydrochloride; Electroacupuncture; Hippocampus; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction

2023
Chronic Pain Syndromes: Fibromyalgia.
    FP essentials, 2023, Volume: 533

    Topics: Chronic Pain; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Milnacipran; Pregabalin

2023
Duloxetine ameliorates the impairment of diffuse noxious inhibitory control in rat models of peripheral neuropathic pain and knee osteoarthritis pain.
    Neuroscience letters, 2020, 06-11, Volume: 729

    Topics: Analgesics; Animals; Chronic Pain; Diffuse Noxious Inhibitory Control; Duloxetine Hydrochloride; Male; Neuralgia; Osteoarthritis, Knee; Pain Measurement; Pregabalin; Rats, Sprague-Dawley

2020
Loss of diffuse noxious inhibitory control after traumatic brain injury in rats: A chronic issue.
    Experimental neurology, 2020, Volume: 333

    Topics: 5,7-Dihydroxytryptamine; Adrenergic Uptake Inhibitors; Animals; Brain Injuries, Traumatic; Capsaicin; Chronic Pain; Diffuse Noxious Inhibitory Control; Duloxetine Hydrochloride; Male; Neural Pathways; Norepinephrine; Pain Measurement; Rats; Rats, Sprague-Dawley; Reboxetine; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents

2020
Reduction in anxiety during treatment with exercise and duloxetine is related to improvement of low back pain-related disability in patients with non-specific chronic low back pain.
    Fukushima journal of medical science, 2020, Volume: 66, Issue:3

    Topics: Adult; Aged; Anxiety; Chronic Pain; Combined Modality Therapy; Disabled Persons; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Low Back Pain; Male; Middle Aged; Prospective Studies

2020
Diet and companionship modulate pain via a serotonergic mechanism.
    Scientific reports, 2021, 02-01, Volume: 11, Issue:1

    Topics: Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chronic Pain; Diet; Disease Models, Animal; Duloxetine Hydrochloride; Female; Fenclonine; Hyperalgesia; Interpersonal Relations; Male; Mice; Mice, Transgenic; Morphine; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Serotonin Antagonists; Signal Transduction; Spinal Cord

2021
Chronic Pain Produces Reversible Memory Deficits That Depend on Task Difficulty in Rats.
    The journal of pain, 2021, Volume: 22, Issue:11

    Topics: Animals; Chronic Pain; Cognitive Dysfunction; Disease Models, Animal; Duloxetine Hydrochloride; Male; Neuralgia; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Serotonin and Noradrenaline Reuptake Inhibitors

2021
Therapeutic effects of diclofenac, pregabalin, and duloxetine on disuse-induced chronic musculoskeletal pain in rats.
    Scientific reports, 2018, 02-19, Volume: 8, Issue:1

    Topics: Animals; Chronic Pain; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Muscle, Skeletal; Muscular Disorders, Atrophic; Musculoskeletal Pain; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley

2018
Duloxetine Improves Spinal Cord Stimulation Outcomes for Chronic Pain.
    Neuromodulation : journal of the International Neuromodulation Society, 2019, Volume: 22, Issue:2

    Topics: Adult; Aged; Analgesics; Analysis of Variance; Chronic Pain; Disability Evaluation; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Psychiatric Status Rating Scales; Regression Analysis; Spinal Cord Stimulation; Treatment Outcome

2019
[With the Characteristics of Chronic Pain Patients, Can the Therapeutic Effect of Antidepressant Duloxetine be Predicted?].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:10

    Topics: Adult; Aged; Antidepressive Agents; Anxiety; Chronic Pain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies

2016
Cost-utility analysis of duloxetine in osteoarthritis: a US private payer perspective.
    Applied health economics and health policy, 2013, Volume: 11, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Humans; Male; Markov Chains; Middle Aged; Models, Economic; Osteoarthritis; Prescription Fees; Thiophenes; United States

2013
[Duloxetine for chronic pain management: pharmacology and clinical use].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Chronic Pain; Depression; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Thiophenes

2013
ACP Journal Club. Review: In neuropathy, fibromyalgia, or chronic pain, duloxetine reduces pain but increases adverse events.
    Annals of internal medicine, 2014, Apr-15, Volume: 160, Issue:8

    Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Thiophenes

2014
Pain management discussion forum: serious interaction among frequently used drugs for chronic pain.
    Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Serotonin Syndrome; Thiophenes; Tramadol

2014
Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats.
    Neuroscience, 2015, Mar-19, Volume: 289

    Topics: Analgesics; Animals; Brain; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Male; Morpholines; Myalgia; Pain Threshold; Pressure; Rats, Sprague-Dawley; Reserpine; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome

2015
Effect of spinal monoaminergic neuronal system dysfunction on pain threshold in rats, and the analgesic effect of serotonin and norepinephrine reuptake inhibitors.
    Neuroscience letters, 2016, Feb-26, Volume: 615

    Topics: Administration, Cutaneous; Analgesics; Animals; Biogenic Monoamines; Brain; Chronic Pain; Cyclopropanes; Duloxetine Hydrochloride; Injections, Spinal; Milnacipran; Neurons; Norepinephrine; Pain Threshold; Rats, Sprague-Dawley; Reserpine; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Spinal Cord; Vesicular Monoamine Transport Proteins

2016
Questions Regarding "Efficacy of Duloxetine in Chronic Low Back Pain with a Neuropathic Component".
    Anesthesiology, 2016, Volume: 125, Issue:1

    Topics: Analgesics; Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Neuralgia; Pain Measurement; Peripheral Nervous System Diseases; Thiophenes

2016
Attentional performance may help to identify duloxetine responders in chronic pain fibromyalgia patients.
    European journal of pain (London, England), 2017, Volume: 21, Issue:6

    Topics: Adult; Aged; Attention; Chronic Pain; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Middle Aged; Neuropsychological Tests; Pain Measurement; Treatment Outcome

2017
Severe Venlafaxine Withdrawal Successfully Treated With a Short Course of Duloxetine.
    The primary care companion for CNS disorders, 2017, Feb-09, Volume: 19, Issue:1

    Topics: Adult; Analgesics; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Neck Pain; Serotonin and Noradrenaline Reuptake Inhibitors; Substance Withdrawal Syndrome; Venlafaxine Hydrochloride

2017
Comparative effectiveness in pain-related outcomes and health care utilizations between veterans with major depressive disorder treated with duloxetine and other antidepressants: a retrospective propensity score-matched comparison.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Analgesics; Antidepressive Agents; Chronic Pain; Cohort Studies; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Retrospective Studies; Thiophenes; Veterans; Young Adult

2012
Does pain improve earlier than mood in depressed patients with painful physical symptoms treated with duloxetine?
    Pharmacopsychiatry, 2012, Volume: 45, Issue:3

    Topics: Adult; Affect; Antidepressive Agents; Chronic Pain; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Prospective Studies; Surveys and Questionnaires; Thiophenes; Time Factors

2012
Antidepressants and the relief of osteoarthritic pain - findings from a study examining adjunctive duloxetine.
    International journal of clinical practice, 2012, Volume: 66, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Chronic Pain; Drug Combinations; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain; Osteoarthritis; Thiophenes; Treatment Outcome

2012
Serotonin syndrome in a patient with chronic pain polypharmacy.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8

    Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol

2014