duloxetine hydrochloride has been researched along with Allodynia in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 30 (61.22) | 24.3611 |
| 2020's | 14 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, S; Mao, M; Wang, J; Wang, X; Zhang, S; Zhou, F | 1 |
| Ishibashi, T; Koga, K; Sueto, D; Tsuda, M; Yamaura, K; Yoshikawa, Y | 1 |
| Chen, H; Chen, SR; Huang, Y; Pan, HL | 1 |
| Bustos-Quevedo, G; Constandil, L; Hernández, A; Lobos, N; Lux, S; Marcos, JL; Pelissier, T; Zepeda, RJ | 1 |
| Jovanović, A; Kotur-Stevuljević, J; Labudović-Borović, M; Micov, A; Nastić, K; Pecikoza, U; Stepanović-Petrović, R; Tomić, M | 1 |
| Djordjevic, JD; Jasnic, NI; Micov, AM; Pecikoza, UB; Stepanović-Petrović, RM; Todorović, MB; Tomić, MA; Vuković, MJ | 1 |
| Bai, J; Jiang, S; Xia, R; Yan, L | 1 |
| Corradini, L; Imam, MZ; Kuo, A; Nicholson, JR; Smith, MT | 1 |
| Awtoniuk, M; Furgała-Wojas, A; Sałat, K; Sałat, R | 1 |
| Egashira, N; Kawashiri, T; Kobayashi, D; Nakamura, H; Shimazoe, T; Uchida, M | 1 |
| Badgaiyan, RD; Gupta, K; Jarrett, S; Palzer, EF; Sagi, V; Tran, H | 1 |
| Makino, K; Nakamura, T; Suzuki, Y; Takahashi, H; Takahashi, Y; Yoshizawa, K | 1 |
| Corradini, L; Kuo, A; Nicholson, JR; Smith, MT | 1 |
| Barros, CM; Boralli, VB; Costa, LH; Galdino, G; Kawano, T; Placido, RV; Podesta, MHMC; Rodrigues, RF; Santos, RS | 1 |
| Chen, M; Hoshino, H; Obata, H; Saito, S; Yang, Y | 1 |
| Balaha, M; Kabel, A; Kandeel, S | 1 |
| An, L; Fan, QY; Fan, SY; Li, J; Li, YF; Ran, YH; Xue, R; Ye, CY; Zhang, LM; Zhang, TT; Zhang, YZ; Zhong, BH; Zhu, L | 1 |
| Alduntzin, U; Barrot, M; Ceredig, RA; Doridot, S; Gaveriaux-Ruff, C; Massotte, D; Pierre, F; Salvat, E; Yalcin, I | 1 |
| Inoue, K; Tozaki-Saitoh, H; Tsuda, M; Yamashita, T | 1 |
| Anandhakrishnan, NK; Gowthamarajan, K; Gulati, M; Jyoti, J; Kapoor, B; Khursheed, R; Kumar, B; Kumar, R; Melkani, I; Mohanta, S; Narang, R; Pandey, NK; Singh, SK; Som, S; Yadav, AK | 1 |
| Aoki, T; Hamakawa, N; Matsuoka, N; Murai, N; Tamura, S; Yamamoto, H | 1 |
| Authier, N; Balayssac, D; Eschalier, A; Ferrier, J; Ling, B; Pereira, B | 1 |
| Dong, YL; Hu, W; Li, HS; Lu, GJ; Sun, YH; Wu, SX; Yang, J; Zhao, GL; Zhu, C | 1 |
| Aoki, T; Matsuoka, N; Murai, N; Tamura, S; Tsukamoto, M | 1 |
| Castagné, V; Le Cudennec, C | 1 |
| Aoki, T; Fushiki, H; Honda, S; Irie, M; Iwashita, A; Murai, N; Murakami, Y; Nagakura, Y; Tamura, S | 1 |
| Russell, G; Strichartz, GR; Wang, CF; Wang, GK | 1 |
| Hoshino, H; Obata, H; Saito, S | 1 |
| Egashira, N; Higuchi, H; Kaname, T; Kawashiri, T; Shirahama, M; Tsutsumi, K; Ushio, S; Yamamoto, S | 1 |
| Averitt, DL; McLean, SA; Nyland, JE | 1 |
| Russell, G; Strichartz, GR; Wang, CF; Wang, GK; Wang, SY | 1 |
| Ceci, A; Doods, H; Hu, B; Treede, RD | 1 |
| Gee, LE; Kaszuba, BC; Pilitsis, JG; Shin, DS; Walling, I | 1 |
| Azmi, S; Boulton, AJM; Calcutt, NA; Efron, N; Fadavi, H; Ferdousi, M; Fineman, MS; Frizzi, K; Jeziorska, M; Jolivalt, CG; Lee-Kubli, C; Malik, RA; Marshall, AG; Mixcoatl-Zecuatl, T; Petropoulos, IN; Ponirakis, G; Tavakoli, M; Zhang, M | 1 |
| Bishnoi, M; Chopra, K; Kuhad, A | 1 |
| Cummons, TA; Harrison, JE; Leventhal, L; Lu, P; Piesla, MJ; Strassle, BW; Whiteside, GT | 1 |
| Dubner, R; Guo, W; Ren, K; Wang, H; Wei, F; Zou, S | 1 |
| Dijkgraaf, MGW; Heesen, M; Hollmann, MW; Kruis, MR; Pijl, AJ; van der Vegt, MH; Vos, K; Vranken, JH | 1 |
| Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS | 1 |
| Jolivalt, CG; Mixcoatl-Zecuatl, T | 1 |
| Bannon, AW; Decker, MW; Gauvin, D; Hsieh, GC; Joshi, SK; Lee, CH; Lewis, LG; Mikusa, J; Mills, CD; Rueter, LE; Zhong, C; Zhu, CZ | 1 |
| Dyhr, H; Erichsen, HK; Hansen, MK; Marcher, L; Munro, G; Sheykhzade, M; Storm, A | 1 |
| Miyazaki, R; Yamamoto, T | 1 |
| Banno, K; Inoue, N; Ito, S; Kotera, T; Kyoi, T; Nakamura, A; Nogawa, M; Sasagawa, T; Tajima, K; Takahashi, Y; Ueda, M; Yamashita, Y | 1 |
| Bannon, AW; Gauvin, DM; Gomez, EJ; Mikusa, J; Mills, CD; Nguyen, T; Salyers, AK; Tanga, FY; Zhong, C | 1 |
| Lluch Girbés, E; López Cubas, C; Nijs, J; Torres-Cueco, R | 1 |
| Jones, CK; Peters, SC; Shannon, HE | 2 |
| Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE | 1 |
1 review(s) available for duloxetine hydrochloride and Allodynia
| Article | Year |
|---|---|
[Green Pharma: A New Strategy for Drug Discovery in Academia by Targeting Glial Cells and ATP Receptors].
Topics: Animals; Disease Models, Animal; Drug Discovery; Duloxetine Hydrochloride; Humans; Hyperalgesia; Injections, Spinal; Molecular Targeted Therapy; Neuralgia; Neuroglia; Purinergic P2X Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4 | 2018 |
1 trial(s) available for duloxetine hydrochloride and Allodynia
| Article | Year |
|---|---|
Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Hyperalgesia; Male; Middle Aged; Neuralgia; Outcome Assessment, Health Care; Pain Measurement; Pain Threshold; Placebo Effect; Spinal Cord Injuries; Stroke; Thiophenes; Treatment Outcome | 2011 |
47 other study(ies) available for duloxetine hydrochloride and Allodynia
| Article | Year |
|---|---|
Participation of transient receptor potential vanilloid 1 in the analgesic effect of duloxetine for paclitaxel induced peripheral neuropathic pain.
Topics: Analgesics; Animals; Antineoplastic Agents; Calcitonin Gene-Related Peptide; Duloxetine Hydrochloride; Ganglia, Spinal; Hyperalgesia; Neuralgia; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Spinal Cord Dorsal Horn; Substance P; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2022 |
Identification of Spinal Inhibitory Interneurons Required for Attenuating Effect of Duloxetine on Neuropathic Allodynia-like Signs in Rats.
Topics: Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Interneurons; Neuralgia; Rats | 2022 |
Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1- and α2-Adrenergic Receptors.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Duloxetine Hydrochloride; Hyperalgesia; Neuralgia; Norepinephrine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Spinal Cord Dorsal Horn; Yohimbine | 2023 |
Rosuvastatin Synergistically Enhances the Antinociceptive Efficacy of Duloxetine in Paclitaxel-Induced Neuropathic Pain in Mice.
Topics: Analgesics; Animals; Duloxetine Hydrochloride; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Mice; Neuralgia; Paclitaxel; Pain Measurement; Rosuvastatin Calcium | 2023 |
The antidepressant drugs vortioxetine and duloxetine differentially and sex-dependently affect animal well-being, cognitive performance, cardiac redox status and histology in a model of osteoarthritis.
Topics: Animals; Antidepressive Agents; Cognition; Duloxetine Hydrochloride; Female; Hyperalgesia; Hypersensitivity; Myocytes, Cardiac; Osteoarthritis; Rats; Vortioxetine | 2023 |
Vortioxetine reduces pain hypersensitivity and associated depression-like behavior in mice with oxaliplatin-induced neuropathy.
Topics: Animals; Antidepressive Agents; Antineoplastic Agents; Behavior, Animal; Brain Stem; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxaliplatin; Pain Measurement; Peripheral Nervous System Diseases; Serotonin; Swimming; Vortioxetine | 2020 |
Successful Reversal of Opioid-Induced Hyperalgesia and Allodynia with Duloxetine.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Hyperalgesia; Morphine; Neuralgia | 2021 |
Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain.
Topics: Analgesics; Animals; Bone and Bones; Cancer Pain; Disease Models, Animal; Duloxetine Hydrochloride; Glycine Plasma Membrane Transport Proteins; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pain Threshold; Pregabalin; Prostatic Neoplasms; Rats; Rats, Wistar | 2020 |
Wide-Range Measurement of Thermal Preference-A Novel Method for Detecting Analgesics Reducing Thermally-Evoked Pain in Mice.
Topics: Analgesics; Animals; Antineoplastic Agents; Cold Temperature; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Mice; Oxaliplatin; Pain; Pain Measurement; Pregabalin; Temperature | 2021 |
Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats.
Topics: Analgesics; Animals; Antineoplastic Agents; Bortezomib; Cold Temperature; Disease Models, Animal; Drugs, Chinese Herbal; Duloxetine Hydrochloride; Humans; Hyperalgesia; Male; Medicine, Kampo; Oxaliplatin; Paclitaxel; Pain Measurement; Rats; Rats, Sprague-Dawley | 2021 |
Diet and companionship modulate pain via a serotonergic mechanism.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chronic Pain; Diet; Disease Models, Animal; Duloxetine Hydrochloride; Female; Fenclonine; Hyperalgesia; Interpersonal Relations; Male; Mice; Mice, Transgenic; Morphine; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Serotonin Antagonists; Signal Transduction; Spinal Cord | 2021 |
Differences in the antinociceptive effects of serotonin-noradrenaline reuptake inhibitors via sodium channel blockade using the veratrine test in mice.
Topics: Animals; Behavior, Animal; Duloxetine Hydrochloride; Hyperalgesia; Mice; Neuralgia; Pain Measurement; Serotonin and Noradrenaline Reuptake Inhibitors; Sodium Channel Blockers; Venlafaxine Hydrochloride | 2021 |
Assessment of the Anti-Allodynic and Anti-Hyperalgesic Efficacy of a Glycine Transporter 2 Inhibitor Relative to Pregabalin, Duloxetine and Indomethacin in a Rat Model of Cisplatin-Induced Peripheral Neuropathy.
Topics: Analgesics; Animals; Benzamides; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Glycine Plasma Membrane Transport Proteins; Hyperalgesia; Indomethacin; Male; Peripheral Nervous System Diseases; Pregabalin; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2021 |
Investigation of the Combination of Pregabalin with Duloxetine or Amitriptyline on the Pharmacokinetics and Antiallodynic Effect During Neuropathic Pain in Rats.
Topics: Amitriptyline; Analgesics; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pregabalin; Rats; Rats, Wistar | 2021 |
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Milnacipran; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Sulpiride | 2017 |
Phloretin either alone or in combination with duloxetine alleviates the STZ-induced diabetic neuropathy in rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Capillaries; Cold Temperature; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Glycated Hemoglobin; Hyperalgesia; Lipids; Male; Oxidative Stress; Phloretin; Rats, Wistar; Sciatic Nerve; Streptozocin; Transaminases | 2018 |
Ammoxetine attenuates diabetic neuropathic pain through inhibiting microglial activation and neuroinflammation in the spinal cord.
Topics: Animals; Benzodioxoles; Calcium-Binding Proteins; Cell Line, Transformed; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Hyperalgesia; Hypoglycemic Agents; Lipopolysaccharides; Locomotion; Microfilament Proteins; Microglia; Myelitis; Propylamines; Rats; Streptozocin | 2018 |
Peripheral delta opioid receptors mediate duloxetine antiallodynic effect in a mouse model of neuropathic pain.
Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Duloxetine Hydrochloride; Female; Ganglia, Spinal; Hyperalgesia; Male; Mice, Transgenic; Neuralgia; Nortriptyline; Pain Measurement; Receptors, Opioid, delta; Sciatic Nerve | 2018 |
A three-pronged formulation approach to improve oral bioavailability and therapeutic efficacy of two lipophilic drugs with gastric lability.
Topics: Analgesics; Animals; Biological Availability; Cold Temperature; Curcumin; Drug Carriers; Duloxetine Hydrochloride; Excipients; Gastric Mucosa; Glutathione; Hot Temperature; Hyperalgesia; Muscle, Skeletal; Neuralgia; Peroxidase; Rats; Sciatic Nerve; Touch; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
AS1069562, the (+)-isomer of indeloxazine, but not duloxetine has a curative-like analgesic effect in a rat model of streptozotocin-induced diabetic neuropathy.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibroblast Growth Factor 2; Ganglia, Spinal; Hyperalgesia; Insulin-Like Growth Factor I; Male; Morpholines; Neural Conduction; Neurotransmitter Uptake Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Streptozocin; Thiophenes; Time Factors | 2014 |
Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models.
Topics: Analgesics; Analgesics, Opioid; Animals; Carrageenan; Cold Temperature; Conditioning, Psychological; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Morphine; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Space Perception; Temperature; Thiophenes | 2014 |
The analgesia effect of duloxetine on post-operative pain via intrathecal or intraperitoneal administration.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Idazoxan; Injections, Intraperitoneal; Injections, Spinal; Ketanserin; Male; Microdialysis; Norepinephrine; Pain, Postoperative; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spinal Cord; Thiophenes | 2014 |
Antinociceptive effects of AS1069562, the (+)-isomer of indeloxazine, on spinal hypersensitivity induced by intrathecal injection of prostaglandin in mice: comparison with duloxetine and amitriptyline.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Spinal; Male; Mice, Inbred ICR; Morpholines; Neuralgia; Prostaglandins; Spinal Cord; Stereoisomerism; Thiophenes | 2014 |
Face-to-face comparison of the predictive validity of two models of neuropathic pain in the rat: analgesic activity of pregabalin, tramadol and duloxetine.
Topics: Analgesics; Animals; Cold Temperature; Disease Models, Animal; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Neuralgia; Physical Stimulation; Pregabalin; Rats, Wistar; Sciatic Nerve; Thiophenes; Tramadol | 2014 |
Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats.
Topics: Analgesics; Animals; Brain; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Male; Morpholines; Myalgia; Pain Threshold; Pressure; Rats, Sprague-Dawley; Reserpine; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome | 2015 |
The Local and Systemic Actions of Duloxetine in Allodynia and Hyperalgesia Using a Rat Skin Incision Pain Model.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Cells, Cultured; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Measurement; Pain, Postoperative; Pituitary Gland; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Sodium Channels; Thiophenes; Time Factors | 2015 |
Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity.
Topics: Amitriptyline; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Lumbosacral Region; Male; Neuronal Plasticity; Norepinephrine; Rats, Sprague-Dawley; Serotonin; Spinal Cord Dorsal Horn; Spinal Nerves; Thiophenes; Time Factors | 2015 |
Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats.
Topics: Administration, Ophthalmic; Analgesics; Animals; Antineoplastic Agents; Axons; Bortezomib; Duloxetine Hydrochloride; Hyperalgesia; Mexiletine; Nerve Degeneration; Neurites; PC12 Cells; Peripheral Nervous System Diseases; Pregabalin; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tramadol | 2015 |
Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury.
Topics: Animals; Behavior, Animal; Burns; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Stress, Psychological | 2015 |
R-Duloxetine and N-Methyl Duloxetine as Novel Analgesics Against Experimental Postincisional Pain.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Cell Line; Duloxetine Hydrochloride; Hyperalgesia; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Neurons; Pain, Postoperative; Patch-Clamp Techniques; Physical Stimulation; Pituitary Gland; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers | 2016 |
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Depression; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Neuralgia; Norepinephrine; Rats, Wistar; Serotonergic Neurons; Serotonin | 2016 |
Effects of subthalamic deep brain stimulation with duloxetine on mechanical and thermal thresholds in 6OHDA lesioned rats.
Topics: Analgesics; Animals; Antiparkinson Agents; Combined Modality Therapy; Deep Brain Stimulation; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Oxidopamine; Pain Threshold; Parkinsonian Disorders; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Subthalamic Nucleus; Touch | 2017 |
Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy.
Topics: Adult; Aged; Analgesics; Animals; Blotting, Western; Case-Control Studies; Cornea; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Hyperalgesia; Hypoglycemic Agents; Insulin; K Cl- Cotransporters; Male; Middle Aged; Neural Inhibition; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Spinal Cord; Symporters | 2017 |
Anti-nociceptive effect of duloxetine in mouse model of diabetic neuropathic pain.
Topics: Adenosine; Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Streptozocin; Thiophenes; Touch | 2009 |
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes | 2009 |
Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: a model of myogenic orofacial pain.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Facial Pain; Hyperalgesia; Ligation; Male; Masseter Muscle; Neuroglia; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tendons; Thiophenes; Trigeminal Nucleus, Spinal | 2010 |
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes | 2011 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Hyperalgesia; Ketanserin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Lameness, Animal; Male; Morphine; Motor Activity; Neuritis; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neuralgia; Neuroma; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors | 2012 |
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Drug Interactions; Duloxetine Hydrochloride; Etodolac; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mexiletine; Mice; Paclitaxel; Peripheral Nervous System Diseases; Pregabalin; Thiophenes; Tissue Distribution | 2012 |
Characterization of nerve growth factor-induced mechanical and thermal hypersensitivity in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Nerve Growth Factor; Pain Threshold; Physical Stimulation; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Thiophenes; TRPV Cation Channels | 2013 |
Pain treatment for patients with osteoarthritis and central sensitization.
Topics: Brain Mapping; Cognitive Behavioral Therapy; Duloxetine Hydrochloride; Exercise Therapy; Humans; Hyperalgesia; Magnetic Resonance Imaging; Neuralgia; Neuroglia; Nociception; Osteoarthritis; Pain Management; Physical Therapy Modalities; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2013 |
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Drug Synergism; Duloxetine Hydrochloride; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 2007 |
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride | 2006 |