Page last updated: 2024-08-24

duloxetine hydrochloride and Ache

duloxetine hydrochloride has been researched along with Ache in 166 studies

Research

Studies (166)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's67 (40.36)29.6817
2010's69 (41.57)24.3611
2020's30 (18.07)2.80

Authors

AuthorsStudies
Chen, B; Duan, J; Pang, J; Wen, S; Zhan, H; Zhang, M; Zheng, Y1
Feng, S; Mao, M; Wang, J; Wang, X; Zhang, S; Zhou, F1
Alberti, FF; Becker, MW; Blatt, CR; da Silva Dal Pizzol, T; Pilger, D; Ziegelmann, PK1
Molassiotis, A; Pei, Z; Wang, M1
Barohn, RJ; Bhai, SF; Brown, A; Gajewski, B; Kimminau, KS; Pasnoor, M; Waitman, LR1
Doucette, JA; Eguale, T; Farag, HM; Goswami, H; Sultan, I; Yunusa, I1
Krusek, J; Mitro, M; Ptakova, A; Vlachova, V; Zimova, L1
Oda, Y; Sato, A; Shimizu, T; Shimoda, K; Shinozaki, M; Suzuki, Y; Yang, M; Yasui-Furukori, N1
Davis, M; Loprinzi, C1
Blalock, M; Chin, JJ; Nguyen, J1
Avallone, A; Bimonte, S; Cardone, C; Cascella, M; Cuomo, A1
Chou, L; Cicuttini, FM; Leaney, AA; Lyttle, JR; Segan, J; Urquhart, DM; Wluka, AE1
Bomfati, F; de Oliveira Filho, GR; Erdmann, TR; Gaspareto, PB; Gerber, MT; Lyra, HF1
Dbar, SR; Degterev, DA; Diukova, GM; Indejkina, LK; Makarova, AA; Parfenov, AI; Romashkina, NV; Ruchkina, IN1
Barry, HC1
Huang, YJ; Ko, YC; Lee, CH; Wu, CS1
Beci, G; Cipolletta, E; Di Carlo, M; Salaffi, F1
Di Carlo, M; Farah, S; Salaffi, F; Sarzi-Puttini, P1
Baroncini, A; Bell, A; Colarossi, G; Eschweiler, J; Maffulli, N; Migliorini, F1
Chen, Y; Li, S; Shi, C; Wang, S; Wen, S; Wu, H; Xu, X; Yu, L; Zhang, T; Zhu, Y1
Blikman, T; Bulstra, SK; Rienstra, W; Stevens, M; van den Akker-Scheek, I1
Dworkin, RH; Gewandter, JS; Mbowe, OB; McDermott, MP; Turk, DC1
Bruno, V; Farcy, N; Karnik, V; Zamorano, C1
Matta, C; Mensah-Nyagan, AG; Meyer, L; Taleb, O1
Ishida, M; Itoh, N; Konno, S; Ochiai, T; Tsuji, T; Uchio, Y1
Ando, R; Iwaki, H; Miyaue, N; Nagai, M; Nishikawa, N; Nomoto, M; Tada, S; Tsujii, T; Yabe, H; Yamanishi, Y1
Han, R; Li, DY; Luo, F; Zhao, ZG1
Edwards, RR; Hunter, DJ; Katz, JN; Lenhard, NK; Losina, E; Neogi, T; Ross, EL; Song, S; Sullivan, JK1
Awtoniuk, M; Furgała-Wojas, A; Sałat, K; Sałat, R1
Bidari, A; Gharibpoor, F; Ghavidel-Parsa, B; Khosousi, MJ; Rahimi, A1
Natsume, T; Ogawa, S; Takamatsu, H1
Hao, A; Hideyama, T; Sato, T; Shibuya, H; Shiio, Y; Tsujimoto, Y1
Najafi, A; Nikvarz, N; Zeinali Nejad, H1
Azami, A; Enteshari-Moghaddam, A; Habibzadeh, A; Isazadehfar, K; Jahanpanah, P; Mohebbi, H1
Chiechio, S; Contino, A; Giuffrida, A; Maccarrone, G; Merlo, S; Pappalardo, G; Parenti, C; Seggio, M1
Kardeş, S1
D'Souza, DN; Frakes, EP; Gaynor, PJ; Hochberg, MC; Risser, RC1
Durakoğlugil, ME; Kaplan, C; Kaya, E; Kocaman, SA; Senol, MG1
Ahl, J; Micca, JL; Ruff, D; Wohlreich, MM1
Bouhassira, D; Cruccu, G; Freynhagen, R; Lledo, A; Schacht, A; Skljarevski, V; Tesfaye, S; Tölle, T; Wilhelm, S1
Finnerup, NB1
Gaynor, PJ; Lipsius, S; Marangell, LB; Namiki, C; Ohara, F; Robinson, MJ; Sheehan, D; Tanaka, Y1
DU, XN; Huang, F; Huang, ZF; Li, Y; Zhang, SL; Zhu, J1
Boulton, AJ; Dickenson, AH; Tesfaye, S1
Malcolm, SK; Risser, RC; Robinson, MJ; Vollmer, TL1
Scheinfeld, N1
Liu, P; Nelson, JC; Oakes, TM; Raskin, J; Robinson, M; Shoemaker, S1
Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y1
Authier, N; Balayssac, D; Eschalier, A; Ferrier, J; Ling, B; Pereira, B1
Kim, YD; Lee, JH; Shim, JH1
Aarons, L; Gueorguieva, I; Yuen, E1
Ishikawa, G; Nagakura, Y; Shimizu, Y; Takeshita, N1
Berggren, L; Gilaberte, I; Lenox-Smith, A; Pérez, V; Quail, D; Romera, I1
Bannon, AW; Joshi, SK; Zhu, CZ1
Dueñas, H; Haro, JM; Hong, J; Moneta, MV; Montgomery, W; Novick, D; Peng, X1
Cappelleri, JC; Ellis, JJ; Mudumby, P; Ndehi, L; Parsons, B; Sadosky, AB; Suehs, BT; Ten Eyck, LL1
Bouhassira, D; Choy, E; Cruccu, G; Freynhagen, R; Kosek, E; Lenox-Smith, A; Lledó, A; Marchettini, P; Micó, JA; Perrot, S; Petto, H; Skljarevski, V; Späth, M; Tesfaye, S; Tölle, T; Wilhelm, S1
Averitt, DL; McLean, SA; Nyland, JE1
Fujikoshi, S; Funai, J; Harada, E; Iwata, N; Ossipov, MH; Tokuoka, H; Wohlreich, MM1
Chen, SL; Long, S; Mao, HJ; Ren, WW; Tang, GZ; Xu, MM; Zhou, ZY1
Hozumi, S; Sekine, A; Shimizu, T1
Brecht, S; Chen, A; Fava, M; Perahia, D; Walker, D; Wiltse, C1
Mallinckrodt, CH; Meyers, AL; Prakash, A; Robinson, MJ; Russell, JM; Sheehan, DV; Swindle, RW1
Forde, G; Stanos, S1
Derry, S; Gaskell, H; Moore, RA; Sultan, A1
Griffith, JM; Hasley, JP; Severn, DG1
Desaiah, D; Montejo, AL; Perahia, DG; Quail, D; Schatzberg, AF1
Eisenach, JC; Hayashida, K1
Chappell, AS; Detke, MJ; Fishbain, DA; Kajdasz, DK; Wernicke, J1
Bentley, S; Fan, MY; Gardner, G; Sullivan, MD1
de Tommaso, M; Ranieri, M; Sardaro, M; Serpino, C; Stasi, M; Vecchio, E1
Voznesenskaia, TG1
Chappell, AS; Detke, MJ; Kajdasz, DK; Mease, PJ; Russell, IJ; Walker, DJ; Wiltse, CG; Wohlreich, MM1
Chancellor, J; Garcia-Cebrian, A; Le, TK; Löthgren, M; Monz, B; Quilici, S; Said, G; Simon, D1
Ememlin, AIu; Kashin, AV; Odinak, MM1
Alda, M; Andrés, E; del Hoyo, YL; García-Campayo, J; Luciano, JV; Magallón, R; Rodero, B; Serrano-Blanco, A1
Chappell, AS; D'Souza, DN; Kajdasz, DK; Littlejohn, G; Moldofsky, H; Scheinberg, M1
Apostolaki, S; Arvaniti, C; Chatzimichael, K; Kitsiou, MC; Kostopanagiotou, G; Matsota, P1
Bennett, RM; Chappell, AS; Collins, H; Iyengar, S; Li, LC; Liu-Seifert, H; Ossanna, MJ; Skljarevski, V1
Ball, S; Beesdo, K; Hartford, J; Russell, J; Spann, M; Wittchen, HU1
Cummons, TA; Harrison, JE; Leventhal, L; Lu, P; Piesla, MJ; Strassle, BW; Whiteside, GT1
Baker, SJ; Boyce-Rustay, JM; Decker, MW; Honore, P; Kohnken, R; Simler, GH; Wensink, EJ; Zhong, C1
Ahl, J; Arnold, LM; Bradley, LA; Choy, EH; Hudson, JI; Mease, PJ; Wang, F; Wohlreich, MM1
Aliaga, M; Bardin, L; Depoortère, R; Gregoire, S; Ladure, P; Malfetes, N; Newman-Tancredi, A; Vitton, O1
Chou, YH; Li, CT; Su, TP1
Staud, R1
Ameri, AA2
Bitter, I; Karamustafalioglu, O; Koponen, H; Mohr, P; Sartorius, N; Seifritz, E; Svestka, J1
Dyhr, H; Grunnet, M; Munro, G1
Bradley, L; Choy, E; Clauw, DJ; Marangell, LB; Mease, P; Shoemaker, S; Wang, F; Wohlreich, MM1
Hettinger, K; Lindsay, TJ; Rodgers, BC; Savath, V1
Cardoner, N; Contreras-Rodríguez, O; Deus, J; Harrison, BJ; Hernández-Ribas, R; López-Solà, M; Menchón, JM; Ortiz, H; Pujol, J; Soriano-Mas, C; Vallejo, J1
Jones, KD; Mist, SD; Ross, RL; Wright, CL1
Cao, Z; Fowler, R; Harnett, J; Mardekian, J; Margolis, J; Sanchez, RJ; Silverman, SL1
Spingler, A1
Spielmans, GI2
Bär, KJ; Berger, S; Boettger, MK; Boettger, S; Terhaar, J; Weiss, T1
Arnold, LM; Bradley, LA; Chappell, AS; Clauw, DJ; Kajdasz, DK; Mease, PJ; Russell, IJ; Spaeth, M; Walker, DJ1
Duenas, H; Gaynor, P; McCarberg, B; Shoemaker, S; Zheng, W1
Marcus, DA1
Liu, X; Mullins, CD; Wang, J1
Boulanger, L; Chen, S; Fraser, K; Wu, N; Zhao, Y; Zhao, Z1
Chokka, PR; Granger, RE; Raskin, J; Sagman, D; Sheehan, DV; Walton, RJ1
Banerjee, M; Griggs, JJ; Hayes, DF; Henry, NL; Schott, AF; Smerage, JB; Van Poznak, C; Wicha, M1
Arnold, LM; Gaynor, PJ; Heinloth, AN; Ruberg, SJ; Wang, F1
Gaynor, PJ; Gopal, M; Hann, D; Marangell, LB; Martinez, JM; Robinson, MJ; Zheng, W1
Gaynor, PJ; Gopal, M; Marangell, LB; Martinez, JM; Robinson, MJ; Zheng, W1
Bernauer, MJ; Boulanger, L; Chen, SY; Fraser, K; Nagar, S; Wu, N; Zhao, Y; Zhao, Z1
Hegerl, U; Hundemer, HP; Linden, M; Quail, D; Schneider, E; Wagner, T; Weigmann, H1
Emel'ianov, VV; Galkin, VV; Nesterova, MV1
Ball, TD; Frakes, EP; Hochberg, MC; Risser, RC; Wohlreich, MM1
Brecht, S; Croenlein, J; Demyttenaere, K; Desaiah, D; Petit, C1
Dyhr, H; Erichsen, HK; Hansen, MK; Marcher, L; Munro, G; Sheykhzade, M; Storm, A1
Boess, FG; Hegerl, U; Linden, M; Mergl, R; Schacht, A; Schneider, E; Wilhelm, S1
Abbar, M; Gilaberte, I; Menchón, JM; Neuhauser, D; Papen, R; Pérez, V; Picard, H; Romera, I; Schacht, A1
Boyle, J; Coppini, DV; Eriksson, ME; Gouni, R; Gribble, L; Johnsen, S; Kerr, D1
Ahl, J; Fijal, BA; Houston, JP; Kohler, J; Ostbye, K1
Fishbain, DA2
Briley, M2
Stewart, DE1
Schatzberg, AF1
Leo, RJ1
Bailey, KP1
Detke, MJ; Fava, M; Mallinckrodt, CH; Watkin, JG; Wohlreich, MM1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Gonzales, JS; Watkin, JG; Wohlreich, MM1
Delgado, PL1
Jones, CK; Peters, SC; Shannon, HE2
Brannan, SK; Brown, EB; Mallinckrodt, CH; Schatzberg, AF; Watkin, JG; Wohlreich, MM1
Blackburn-Munro, G; Bomholt, SF; Mikkelsen, JD1
Detke, MJ; Kennedy, JS; Mallinckrodt, CH; Nelson, JC; Watkin, JG; Wohlreich, MM1
Konarski, JZ; McIntyre, RS1
Bauer, M; Möller, HJ; Schneider, E1
Das, A; Desarkar, P; Sinha, VK1
Russell, JW1
Desaiah, D; Perahia, DG; Pritchett, YL; Raskin, J1
D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Tran, P; Waninger, A; Wernicke, JF1
O'Connor, AB1
Hajak, G1
Ziegler, D1
Meighen, KG1
Terneus, W1
Colman, SA; Harrison, GA; Hong, JP; Lee, MS; Lee, P; Liu, CY; Raskin, J; Ruschel, S; Shu, L; Wang, CY; Xu, X1
Wallace, JM1
Dinkel, JJ; Mohs, RC; Raskin, J; Rotz, BT; Sheikh, J; Siegal, A; Wiltse, CG; Xu, J1
Leventhal, L; Piesla, M; Wantuch, C1
D'Souza, DN; Erickson, JS; Fava, M; Hartford, JT; Russell, JM; Weisberg, R1
Iosifescu, DV; Raskin, J; Sheridan, M; Wiltse, CG; Wise, TN; Xu, JY1
Cohen, LS; Joffe, H; Koch, JK; Petrillo, LF; Soares, CN; Somley, BL; Viguera, AC1
Cole, BE1
Armstrong, DG; Wrobel, JS; Wu, SC1
Robinson-Papp, J; Simpson, DM1
Brecht, S; Courtecuisse, C; Croenlein, J; Debieuvre, C; Demyttenaere, K; Desaiah, D; Petit, C; Raskin, J1
Möller, HJ; Müller, N; Riedel, M; Schennach, R1
Fishbain, DA; Gonzales, J; Hall, J; Mallinckrodt, C; Meyers, AL1

Reviews

41 review(s) available for duloxetine hydrochloride and Ache

ArticleYear
An Updated Systematic Review and Meta-analysis of Duloxetine for Knee Osteoarthritis Pain.
    The Clinical journal of pain, 2021, 11-01, Volume: 37, Issue:11

    Topics: Duloxetine Hydrochloride; Humans; Knee Joint; Osteoarthritis, Knee; Pain; Pain Measurement

2021
Comparative efficacy of amitriptyline, duloxetine and pregabalin for treating fibromyalgia in adults: an overview with network meta-analysis.
    Clinical rheumatology, 2022, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Amitriptyline; Child; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Network Meta-Analysis; Pain; Pregabalin; Randomized Controlled Trials as Topic

2022
Recent advances in managing chemotherapy-induced peripheral neuropathy: A systematic review.
    European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2022, Volume: 58

    Topics: Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Pain; Pain Management; Peripheral Nervous System Diseases

2022
Comparison of Amitriptyline and US Food and Drug Administration-Approved Treatments for Fibromyalgia: A Systematic Review and Network Meta-analysis.
    JAMA network open, 2022, 05-02, Volume: 5, Issue:5

    Topics: Amitriptyline; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Network Meta-Analysis; Pain; Pregabalin; United States; United States Food and Drug Administration

2022
Pregabalin for chemotherapy-induced neuropathy: background and rationale for further study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:11

    Topics: Analgesics; Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Treatment Outcome

2022
Pathophysiology and Therapeutic Perspectives for Chemotherapy-induced Peripheral Neuropathy.
    Anticancer research, 2022, Volume: 42, Issue:10

    Topics: Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Quality of Life

2022
Antidepressants for hip and knee osteoarthritis.
    The Cochrane database of systematic reviews, 2022, 10-21, Volume: 10

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Quality of Life; Randomized Controlled Trials as Topic

2022
Efficacy and safety of duloxetine in painful diabetic peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials.
    Systematic reviews, 2023, 03-21, Volume: 12, Issue:1

    Topics: Diabetes Mellitus; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Quality of Life; Randomized Controlled Trials as Topic

2023
Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2023, Jul-17, Volume: 18, Issue:1

    Topics: Adult; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2023
Current Status of Pain Management in Parkinson's Disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:3

    Topics: Acetylcholine Release Inhibitors; Alanine; Analgesics; Antiparkinson Agents; Apomorphine; Benzylamines; Botulinum Toxins, Type A; Deep Brain Stimulation; Dopamine Agonists; Drug Combinations; Duloxetine Hydrochloride; Humans; Levodopa; Naloxone; Oxycodone; Pain; Pain Management; Pain Measurement; Pain Threshold; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes

2020
Mechanisms and management of diabetic painful distal symmetrical polyneuropathy.
    Diabetes care, 2013, Volume: 36, Issue:9

    Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Thiophenes

2013
Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine.
    Dermatology online journal, 2013, Nov-15, Volume: 19, Issue:11

    Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hidradenitis Suppurativa; Humans; Pain; Pain Management; Pregabalin; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Thiophenes; Venlafaxine Hydrochloride

2013
Is duloxetine's effect on painful physical symptoms in depression an indirect result of improvement of depressive symptoms? Pooled analyses of three randomized controlled trials.
    Pain, 2016, Volume: 157, Issue:3

    Topics: Analgesics; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome

2016
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome

2007
Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials.
    BMC neurology, 2008, Aug-01, Volume: 8

    Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2008
The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder.
    Current medical research and opinion, 2008, Volume: 24, Issue:11

    Topics: Adult; Analgesia; Analgesics; Antidepressive Agents; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2008
Central sensitisation phenomena in primary headaches: overview of a preventive therapeutic approach.
    CNS & neurological disorders drug targets, 2008, Volume: 7, Issue:6

    Topics: Animals; Duloxetine Hydrochloride; Fibromyalgia; Headache; Humans; Migraine Disorders; Pain; Pain Management; Sleep Deprivation; Thiophenes

2008
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain.
    BMC neurology, 2009, Feb-10, Volume: 9

    Topics: Amines; Analgesics; Analysis of Variance; Bayes Theorem; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2009
Comparative pain and mood effects in patients with comorbid fibromyalgia and major depressive disorder: secondary analyses of four pooled randomized controlled trials of duloxetine.
    Pain, 2011, Volume: 152, Issue:1

    Topics: Adult; Affect; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes

2011
Treating diabetic peripheral neuropathic pain.
    American family physician, 2010, Jul-15, Volume: 82, Issue:2

    Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Complementary Therapies; Diabetic Neuropathies; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Pregabalin; Recovery of Function; Thiophenes

2010
Duloxetine for the treatment of fibromyalgia.
    Expert review of clinical immunology, 2010, Volume: 6, Issue:5

    Topics: Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pain Measurement; Thiophenes

2010
Weight change with long-term duloxetine use in chronic painful conditions: an analysis of 16 clinical studies.
    International journal of clinical practice, 2011, Volume: 65, Issue:3

    Topics: Aged; Analgesics; Arthralgia; Chronic Disease; Controlled Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Knee Joint; Low Back Pain; Male; Middle Aged; Osteoarthritis, Knee; Pain; Thiophenes; Weight Gain; Weight Loss

2011
New hope in the treatment of painful symptoms in depression.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:1

    Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Cyclohexanols; Cyclopropanes; Depressive Disorder; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride

2003
Physical symptoms of depression: unmet needs in special populations.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 7

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Age Factors; Antidepressive Agents; Child; Comorbidity; Cyclohexanols; Delivery of Health Care; Depressive Disorder; Diagnosis, Differential; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Poverty; Selective Serotonin Reuptake Inhibitors; Sex Factors; Thiophenes; Venlafaxine Hydrochloride

2003
Efficacy and tolerability of duloxetine, a novel dual reuptake inhibitor, in the treatment of major depressive disorder.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 13

    Topics: Adrenergic Uptake Inhibitors; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Norepinephrine; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin; Somatoform Disorders; Thiophenes; Treatment Outcome

2003
Physical symptoms comorbid with depression and the new antidepressant duloxetine.
    Journal of psychosocial nursing and mental health services, 2003, Volume: 41, Issue:12

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Anxiety Disorders; Comorbidity; Depressive Disorder; Duloxetine Hydrochloride; Gastrointestinal Diseases; Humans; Mood Disorders; Norepinephrine; Pain; Psychophysiologic Disorders; Selective Serotonin Reuptake Inhibitors; Serotonin; Sleep Wake Disorders; Thiophenes; Treatment Outcome

2003
The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:4

    Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome

2004
Common pathways of depression and pain.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 12

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanols; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Norepinephrine; Pain; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Clinical experience with dual action antidepressants in different chronic pain syndromes.
    Human psychopharmacology, 2004, Volume: 19 Suppl 1

    Topics: Antidepressive Agents; Chronic Disease; Cyclohexanols; Cyclopropanes; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride

2004
Duloxetine: pharmacoeconomic implications of an antidepressant that alleviates painful physical symptoms.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:5

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Economics, Pharmaceutical; Humans; Pain; Pain Measurement; Thiophenes

2005
Duloxetine: a new selective and dual-acting antidepressant.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Pain; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2006
Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect?
    International clinical psychopharmacology, 2006, Volume: 21, Issue:6

    Topics: Analgesics; Antidepressive Agents; Chronic Disease; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Thiophenes; Treatment Outcome

2006
[Dual acting reuptake inhibitors in the treatment of depression and pain].
    Deutsche medizinische Wochenschrift (1946), 2006, Volume: 131 Suppl 8

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Depression; Diabetes Complications; Diabetes Mellitus, Type 2; Duloxetine Hydrochloride; Humans; Norepinephrine; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Treatment Outcome

2006
[Duloxetine, a new therapeutic option for diabetic peripheral neuropathic pain].
    Deutsche medizinische Wochenschrift (1946), 2006, Volume: 131 Suppl 8

    Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Quality of Life; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2006
Update on pharmacotherapy guidelines for treatment of neuropathic pain.
    Current pain and headache reports, 2007, Volume: 11, Issue:3

    Topics: Analgesics; Animals; Cannabidiol; Chronic Disease; Dronabinol; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Guidelines as Topic; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Thiophenes

2007
Efficacy of duloxetine in the treatment of generalized anxiety disorder in patients with clinically significant pain symptoms.
    Depression and anxiety, 2008, Volume: 25, Issue:7

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pain; Pain Measurement; Personality Inventory; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2008
Diabetic peripheral neuropathic pain: recognition and management.
    Pain medicine (Malden, Mass.), 2007, Volume: 8 Suppl 2

    Topics: Antidepressive Agents; Diabetic Foot; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Thiophenes

2007
Assessing the impact of pharmacologic intervention on the quality of life in diabetic peripheral neuropathic pain and fibromyalgia.
    Pain medicine (Malden, Mass.), 2007, Volume: 8 Suppl 2

    Topics: Antidepressive Agents; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Quality of Life; Randomized Controlled Trials as Topic; Thiophenes

2007
Safety profile of treatment in diabetic peripheral neuropathic pain.
    Pain medicine (Malden, Mass.), 2007, Volume: 8 Suppl 2

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanols; Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Thiophenes; Venlafaxine Hydrochloride

2007
Duloxetine does not relieve painful physical symptoms in depression: a meta-analysis.
    Psychotherapy and psychosomatics, 2008, Volume: 77, Issue:1

    Topics: Adult; Analgesics; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Paroxetine; Psychophysiologic Disorders; Randomized Controlled Trials as Topic; Somatoform Disorders; Thiophenes; Treatment Outcome

2008
Duloxetine in the treatment of major psychiatric and neuropathic disorders.
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:4

    Topics: Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress

2008

Trials

49 trial(s) available for duloxetine hydrochloride and Ache

ArticleYear
A secondary analysis of PAIN-CONTRoLS: Pain's impact on sleep, fatigue, and activities of daily living.
    Muscle & nerve, 2022, Volume: 66, Issue:4

    Topics: Activities of Daily Living; Bayes Theorem; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Fatigue; Humans; Mexiletine; Nortriptyline; Pain; Pregabalin; Prospective Studies; Quality of Life; Sleep; Treatment Outcome

2022
Efficacy of postoperative analgesia with duloxetine in posthemorrhoidectomy pain: a prospective, randomized, double-blind and placebo-controlled trial.
    BMC anesthesiology, 2022, 12-01, Volume: 22, Issue:1

    Topics: Analgesia; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Humans; Morphine; Pain; Prospective Studies

2022
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
    Terapevticheskii arkhiv, 2022, Sep-05, Volume: 94, Issue:2S

    Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Serotonin and Noradrenaline Reuptake Inhibitors; Trimebutine

2022
Palmitoylethanolamide and acetyl-L-carnitine act synergistically with duloxetine and pregabalin in fibromyalgia: results of a randomised controlled study.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:6

    Topics: Acetylcarnitine; Analgesics; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pregabalin; Treatment Outcome

2023
A randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough.
    BMC pulmonary medicine, 2023, Aug-02, Volume: 23, Issue:1

    Topics: Cough; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pain; Prospective Studies; Quality of Life; Tablets, Enteric-Coated; Treatment Outcome

2023
Efficacy of duloxetine for multisite pain in patients with knee pain due to osteoarthritis: An exploratory post hoc analysis of a Japanese phase 3 randomized study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2021, Volume: 26, Issue:1

    Topics: Double-Blind Method; Duloxetine Hydrochloride; Humans; Japan; Osteoarthritis, Knee; Pain; Pain Measurement; Treatment Outcome

2021
A double-blind, randomized controlled trial of duloxetine for pain in Parkinson's disease.
    Journal of the neurological sciences, 2020, Jul-15, Volume: 414

    Topics: Dopamine Agents; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pain; Parkinson Disease; Treatment Outcome

2020
Duloxetine combined with intra-articular injection versus intra-articular injection alone for pain relief in knee osteoarthritis: a study protocol for a randomised controlled trial.
    BMJ open, 2020, 10-27, Volume: 10, Issue:10

    Topics: Duloxetine Hydrochloride; Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis, Knee; Pain; Pain Management; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome

2020
No effect of approved fibromyalgia drugs on the social pain (invalidation) contrary to physical pain: an open-label short-term randomized clinical trial.
    Clinical rheumatology, 2022, Volume: 41, Issue:1

    Topics: Analgesics; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pharmaceutical Preparations; Pregabalin; Treatment Outcome

2022
Evaluation of the analgesic effects of duloxetine in burn patients: An open-label randomized controlled trial.
    Burns : journal of the International Society for Burn Injuries, 2019, Volume: 45, Issue:3

    Topics: Adult; Analgesics; Burns; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Pain Management; Pain Measurement; Pain, Procedural; Treatment Outcome

2019
Efficacy of duloxetine and gabapentin in pain reduction in patients with knee osteoarthritis.
    Clinical rheumatology, 2019, Volume: 38, Issue:10

    Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Duloxetine Hydrochloride; Female; Gabapentin; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Management; Pain Measurement; Quality of Life; Rheumatology; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Visual Analog Scale

2019
Responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) scale in a trial of duloxetine for treatment of osteoarthritis knee pain.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2013
Safety and efficacy of duloxetine treatment in older and younger patients with osteoarthritis knee pain: a post hoc, subgroup analysis of two randomized, placebo-controlled trials.
    BMC musculoskeletal disorders, 2013, Apr-17, Volume: 14

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2013
Duloxetine and pregabalin: high-dose monotherapy or their combination? The "COMBO-DN study"--a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain.
    Pain, 2013, Volume: 154, Issue:12

    Topics: Aged; Analgesics; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Internationality; Male; Middle Aged; Pain; Pregabalin; Thiophenes; Treatment Outcome

2013
Relationship between major depressive disorder and associated painful physical symptoms: analysis of data from two pooled placebo-controlled, randomized studies of duloxetine.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:6

    Topics: Adult; Analgesics; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Statistics as Topic; Thiophenes

2013
[Impact of duloxetine on depression and anxiety in patients with ankylosing spondylitis: a case-control study].
    Zhonghua yi xue za zhi, 2013, Apr-02, Volume: 93, Issue:13

    Topics: Adult; Analgesics; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Spondylitis, Ankylosing; Thiophenes; Young Adult

2013
A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of pain in patients with multiple sclerosis.
    Pain practice : the official journal of World Institute of Pain, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Analgesics; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Pain; Thiophenes; Treatment Outcome

2014
Acute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2014, Volume: 22, Issue:1

    Topics: Age of Onset; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Psychiatric Status Rating Scales; Thiophenes

2014
Are there different predictors of analgesic response between antidepressants and anticonvulsants in painful diabetic neuropathy?
    European journal of pain (London, England), 2016, Volume: 20, Issue:3

    Topics: Affect; Age Factors; Aged; Analgesics; Anticonvulsants; Antidepressive Agents; Anxiety; Depression; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pregabalin; Psychiatric Status Rating Scales; Treatment Outcome

2016
[Treatment of Persistent Somatoform Pain Disorder by Floating Needle Therapy and Duloxetine].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2016, Volume: 36, Issue:2

    Topics: Acupuncture Therapy; Analgesics; Anxiety Disorders; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Needles; Pain; Pain Management; Pain Measurement; Psychiatric Status Rating Scales; Somatoform Disorders; Treatment Outcome

2016
Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder.
    Journal of affective disorders, 2009, Volume: 113, Issue:3

    Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Predictive Value of Tests; Prevalence; Prospective Studies; Recurrence; Severity of Illness Index; Thiophenes

2009
The relationship between functional outcomes and the treatment of anxious and painful somatic symptoms in patients with generalized anxiety disorder.
    Current medical research and opinion, 2008, Volume: 24, Issue:9

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Placebos; Psychophysiologic Disorders; Thiophenes; Treatment Outcome

2008
Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression.
    Journal of psychiatric research, 2009, Volume: 43, Issue:5

    Topics: Activities of Daily Living; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Europe; Female; Health Surveys; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Time Factors; Treatment Outcome

2009
A single-blind, placebo run-in study of duloxetine for activity-limiting osteoarthritis pain.
    The journal of pain, 2009, Volume: 10, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Single-Blind Method; Thiophenes; Time Factors; Treatment Outcome

2009
Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia.
    Seminars in arthritis and rheumatism, 2010, Volume: 39, Issue:6

    Topics: Antidepressive Agents; Depression; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Health Status; Humans; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2010
[Cymbalta in the treatment of chronic pain syndromes].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:3

    Topics: Adult; Antidepressive Agents; Chronic Disease; Depression; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Middle Aged; Pain; Pain Measurement; Syndrome; Thiophenes; Treatment Outcome

2009
Effectiveness of the psychological and pharmacological treatment of catastrophization in patients with fibromyalgia: a randomized controlled trial.
    Trials, 2009, Apr-23, Volume: 10

    Topics: Adolescent; Adult; Aged; Analgesics; Antidepressive Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Depression; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain; Pain Management; Pain Measurement; Pregabalin; Psychiatric Status Rating Scales; Research Design; Spain; Thiophenes; Time Factors; Treatment Outcome; Young Adult

2009
A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia.
    The Clinical journal of pain, 2009, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Comorbidity; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Internationality; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome; Young Adult

2009
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial.
    Pain, 2009, Volume: 146, Issue:3

    Topics: Aged; Analgesics; Antidepressive Agents; Depression; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Knee; Male; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome

2009
Pseudohypoalgesia on the skin: a novel view on the paradox of pain perception in depression.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:1

    Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Temperature; Humans; Male; Middle Aged; Pain; Pain Measurement; Pain Perception; Pain Threshold; Skin Physiological Phenomena; Thiophenes

2011
Estimation of minimum clinically important difference for pain in fibromyalgia.
    Arthritis care & research, 2011, Volume: 63, Issue:6

    Topics: Adult; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Thiophenes

2011
Clinical and functional outcomes in patients with major depressive disorder and painful physical symptoms switched to treatment with duloxetine.
    Human psychopharmacology, 2011, Volume: 26, Issue:3

    Topics: Adult; Depressive Disorder, Major; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2011
Pilot study of duloxetine for treatment of aromatase inhibitor-associated musculoskeletal symptoms.
    Cancer, 2011, Dec-15, Volume: 117, Issue:24

    Topics: Adult; Aged; Aromatase Inhibitors; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Musculoskeletal Diseases; Pain; Pilot Projects; Postmenopause; Selective Serotonin Reuptake Inhibitors; Thiophenes

2011
Early improvement in pain predicts pain response at endpoint in patients with fibromyalgia.
    The journal of pain, 2011, Volume: 12, Issue:10

    Topics: Adult; Dopamine Uptake Inhibitors; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Predictive Value of Tests; Regression Analysis; Thiophenes; Time Factors

2011
Duloxetine versus placebo in the treatment of major depressive disorder and associated painful physical symptoms: a replication study.
    Current medical research and opinion, 2011, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Pain; Puerto Rico; Remission Induction; Thiophenes; Time Factors; United States

2011
A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms.
    Current medical research and opinion, 2011, Volume: 27, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Remission Induction; Thiophenes; Time Factors

2011
Early reduction in painful physical symptoms is associated with improvements in long-term depression outcomes in patients treated with duloxetine.
    BMC psychiatry, 2011, Sep-20, Volume: 11

    Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; International Classification of Diseases; Male; Middle Aged; Outpatients; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Thiophenes

2011
[Biological age and the pain syndrome at diabetic polyneuropathy].
    Advances in gerontology = Uspekhi gerontologii, 2011, Volume: 24, Issue:2

    Topics: Adult; Aging; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes; Treatment Outcome

2011
Duloxetine added to oral nonsteroidal anti-inflammatory drugs for treatment of knee pain due to osteoarthritis: results of a randomized, double-blind, placebo-controlled trial.
    Current medical research and opinion, 2011, Volume: 27, Issue:12

    Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Knee; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Management; Thiophenes; Time Factors

2011
Early vs. conventional switching of antidepressants in patients with MDD and moderate to severe pain: a double-blind randomized study.
    Journal of affective disorders, 2012, Dec-20, Volume: 143, Issue:1-3

    Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome; Young Adult

2012
Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life.
    Diabetes care, 2012, Volume: 35, Issue:12

    Topics: Aged; Amitriptyline; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pregabalin; Quality of Life; Sleep; Thiophenes; Treatment Outcome

2012
The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:4

    Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome

2004
Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder.
    Journal of psychiatric research, 2005, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Placebos; Severity of Illness Index; Thiophenes; Treatment Outcome

2005
A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain.
    Neurology, 2006, Oct-24, Volume: 67, Issue:8

    Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Aged; Analgesics, Non-Narcotic; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Norepinephrine; Pain; Palliative Care; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome

2006
Once-daily duloxetine 60 mg in the treatment of major depressive disorder: multicenter, double-blind, randomized, paroxetine-controlled, non-inferiority trial in China, Korea, Taiwan and Brazil.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:3

    Topics: Activities of Daily Living; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Pressure; Brazil; China; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Korea; Male; Middle Aged; Pain; Pain Measurement; Paroxetine; Psychiatric Status Rating Scales; Taiwan; Thiophenes; Weight Gain

2007
Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial.
    The American journal of psychiatry, 2007, Volume: 164, Issue:6

    Topics: Age Factors; Aged; Antidepressive Agents; Back Pain; Cognition Disorders; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Geriatric Assessment; Humans; Male; Neuropsychological Tests; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Secondary Prevention; Thiophenes; Treatment Outcome

2007
The safety and tolerability of duloxetine in depressed elderly patients with and without medical comorbidity.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Arthritis; Cardiovascular Diseases; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Pain Measurement; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:6

    Topics: Adult; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Middle Aged; Pain; Postmenopause; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Sleep Wake Disorders; Thiophenes; Treatment Outcome

2007
Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Thiophenes

2007

Other Studies

77 other study(ies) available for duloxetine hydrochloride and Ache

ArticleYear
Participation of transient receptor potential vanilloid 1 in the analgesic effect of duloxetine for paclitaxel induced peripheral neuropathic pain.
    Neuroscience letters, 2022, 03-16, Volume: 773

    Topics: Analgesics; Animals; Antineoplastic Agents; Calcitonin Gene-Related Peptide; Duloxetine Hydrochloride; Ganglia, Spinal; Hyperalgesia; Neuralgia; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Spinal Cord Dorsal Horn; Substance P; TRPV Cation Channels; Tumor Necrosis Factor-alpha

2022
Activity dependent inhibition of TRPC1/4/5 channels by duloxetine involves voltage sensor-like domain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 152

    Topics: Duloxetine Hydrochloride; HEK293 Cells; Humans; Molecular Docking Simulation; Pain; TRPC Cation Channels

2022
Asymptomatic syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following duloxetine treatment for pain with depression: Two case reports.
    Neuropsychopharmacology reports, 2022, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Depression; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Mianserin; Pain; Venlafaxine Hydrochloride

2022
Probable drug-induced clitoral priapism due to potentiating effects of pregabalin and duloxetine.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2023, 01-01, Volume: 80, Issue:1

    Topics: Analgesics; Clitoris; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pregabalin; Priapism; Probability

2023
Amitriptyline, Duloxetine, and Pregabalin Each Effective in Decreasing Pain From Diabetic Peripheral Neuropathy; Combinations Even Better.
    American family physician, 2023, Volume: 107, Issue:3

    Topics: Amitriptyline; Analgesics; Diabetes Mellitus; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Pregabalin

2023
Predicting acupuncture efficacy in fibromyalgia: results of a pragmatic open-label study.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:6

    Topics: Acupuncture Therapy; Duloxetine Hydrochloride; Fibromyalgia; Humans; Male; Pain; Research Design

2023
Responsiveness and interpretability of the pain subscale of the Knee and Hip Osteoarthritis Outcome Scale (KOOS and HOOS) in osteoarthritis patients according to COSMIN guidelines.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Arthroplasty, Replacement, Hip; Duloxetine Hydrochloride; Humans; Knee Joint; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain

2023
Are there really only 2 kinds of people in the world? Evaluating the distribution of change from baseline in pain clinical trials.
    Pain, 2020, Volume: 161, Issue:1

    Topics: Analgesics; Clinical Trials as Topic; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Pain Management; Pain Measurement; Pregabalin; Research Design; Treatment Outcome

2020
Behavioral, Electrophysiological, and Histological Characterization of a New Rat Model for Neoadjuvant Chemotherapy-Induced Neuropathic Pain: Therapeutic Potential of Duloxetine and Allopregnanolone Concomitant Treatment.
    Neurotoxicity research, 2020, Volume: 38, Issue:1

    Topics: Analgesics; Animals; Antineoplastic Agents; Disease Models, Animal; Docetaxel; Duloxetine Hydrochloride; Epirubicin; Female; Neoadjuvant Therapy; Neuralgia; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregnanolone; Sciatic Nerve

2020
Does Screening for Depressive Symptoms Help Optimize Duloxetine Use in Knee Osteoarthritis Patients With Moderate Pain? A Cost-Effectiveness Analysis.
    Arthritis care & research, 2022, Volume: 74, Issue:5

    Topics: Cost-Benefit Analysis; Depression; Duloxetine Hydrochloride; Humans; Osteoarthritis, Knee; Pain

2022
Wide-Range Measurement of Thermal Preference-A Novel Method for Detecting Analgesics Reducing Thermally-Evoked Pain in Mice.
    Molecules (Basel, Switzerland), 2021, Jan-25, Volume: 26, Issue:3

    Topics: Analgesics; Animals; Antineoplastic Agents; Cold Temperature; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Mice; Oxaliplatin; Pain; Pain Measurement; Pregabalin; Temperature

2021
[Pharmacological profile of a novel nonhuman primate model of knee osteoarthritis].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2018, Volume: 152, Issue:3

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aprepitant; Diclofenac; Duloxetine Hydrochloride; Knee Joint; Morphine; Neurokinin-1 Receptor Antagonists; Osteoarthritis, Knee; Pain; Primates; Serotonin and Noradrenaline Reuptake Inhibitors

2018
[Anti-Hu antibody positive sensory neuronopathy causing painful legs and moving toes (PLMT) in a 75-year-old female with small cell lung cancer (SCLC)].
    Rinsho shinkeigaku = Clinical neurology, 2018, Nov-28, Volume: 58, Issue:11

    Topics: Aged; Antineoplastic Agents; Ataxia; Autoantibodies; Duloxetine Hydrochloride; ELAV Proteins; Female; Humans; Immunoglobulins, Intravenous; Leg; Lung Neoplasms; Movement Disorders; Pain; Paraneoplastic Polyneuropathy; Paraneoplastic Syndromes; Paresthesia; Small Cell Lung Carcinoma; Toes

2018
Preclinical evidence of enhanced analgesic activity of duloxetine complexed with succinyl-β-cyclodextrin: A comparative study with cyclodextrin complexes.
    International journal of pharmaceutics, 2019, Jul-20, Volume: 566

    Topics: Analgesics; Animals; Caco-2 Cells; Cell Survival; Cyclodextrins; Cytochrome P-450 CYP2D6; Duloxetine Hydrochloride; Humans; Male; Mice; Pain

2019
Comment on "Efficacy of duloxetine and gabapentin in pain reduction in patients with knee osteoarthritis".
    Clinical rheumatology, 2019, Volume: 38, Issue:11

    Topics: Analgesics; Duloxetine Hydrochloride; Gabapentin; Humans; Osteoarthritis, Knee; Pain

2019
Duloxetine reduces chemotherapy induced peripheral neuropathy.
    BMJ (Clinical research ed.), 2013, Apr-10, Volume: 346

    Topics: Antidepressive Agents; Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Thiophenes

2013
Cardiac syncope due to pain: report of a case responsive to duloxetine treatment.
    Herz, 2013, Volume: 38, Issue:6

    Topics: Adult; Analgesics; Duloxetine Hydrochloride; Female; Humans; Pain; Syncope; Thiophenes; Treatment Outcome

2013
Add-on therapy: when two are not better than one.
    Pain, 2013, Volume: 154, Issue:12

    Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Pain; Pregabalin; Thiophenes

2013
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2014
Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models.
    Behavioural pharmacology, 2014, Volume: 25, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Carrageenan; Cold Temperature; Conditioning, Psychological; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Morphine; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Space Perception; Temperature; Thiophenes

2014
Duloxetine in the treatment of burning mouth syndrome refractory to conventional treatment: A case report.
    The Journal of international medical research, 2014, Volume: 42, Issue:3

    Topics: Aged; Analgesics; Burning Mouth Syndrome; Duloxetine Hydrochloride; Female; Humans; Lidocaine; Lingual Nerve; Nerve Block; Pain; Quality of Life; Stellate Ganglion; Treatment Outcome; Triamcinolone

2014
Handling missing data in a duloxetine population pharmacokinetic/pharmacodynamic model - imputation methods and selection models.
    Pharmaceutical research, 2014, Volume: 31, Issue:10

    Topics: Analgesics; Computer Simulation; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Models, Biological; Nonlinear Dynamics; Pain; Pain Measurement; Patient Dropouts; Probability; Randomized Controlled Trials as Topic; Thiophenes

2014
Efficacy of drugs with different mechanisms of action in relieving spontaneous pain at rest and during movement in a rat model of osteoarthritis.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Duloxetine Hydrochloride; Gait; Iodoacetic Acid; Male; Morphine; Movement; Osteoarthritis; Pain; Rats; Rest; Thiophenes; Tramadol; Weight-Bearing

2014
Individual residual symptoms and functional impairment in patients with depression.
    Psychiatry research, 2014, Dec-15, Volume: 220, Issue:1-2

    Topics: Adult; Antidepressive Agents; Anxiety; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Sleep Wake Disorders; Thiophenes

2014
Complete Freund's adjuvant-induced reduction of exploratory activity in a novel environment as an objective nociceptive endpoint for sub-acute inflammatory pain model in rats.
    European journal of pain (London, England), 2015, Volume: 19, Issue:10

    Topics: Adjuvants, Immunologic; Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley

2015
Real-world outcomes in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia.
    Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2016, Volume: 8, Issue:1

    Topics: Adult; Asia, Eastern; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Pain; Paroxetine; Prospective Studies; Quality of Life; Regression Analysis; Remission Induction; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sertraline; Severity of Illness Index; Treatment Outcome

2016
A retrospective, matched cohort study of potential drug-drug interaction prevalence and opioid utilization in a diabetic peripheral neuropathy population initiated on pregabalin or duloxetine.
    BMC health services research, 2015, Apr-15, Volume: 15

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cohort Studies; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Medicare Part C; Middle Aged; Pain; Pregabalin; Prescription Drugs; Prevalence; Retrospective Studies; United States; Young Adult

2015
Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8

    Topics: Animals; Behavior, Animal; Burns; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Stress, Psychological

2015
Influence of painful physical symptoms in the treatment of Japanese patients with melancholic major depressive disorder: A prospective cohort study.
    Psychiatry research, 2016, Aug-30, Volume: 242

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Comorbidity; Cyclopropanes; Depressive Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Milnacipran; Pain; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Treatment Outcome

2016
Measurement of pain and medication effect in a study of duloxetine.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:6

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Prevalence; Severity of Illness Index; Thiophenes

2008
Multiplicative interactions to enhance gabapentin to treat neuropathic pain.
    European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Indans; Injections, Spinal; Ligation; Male; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Nerves; Thiophenes

2008
[Chronic pain and depression].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:11

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Prevalence; Thiophenes

2008
Successful pain relief of cutaneous leiomyomata due to reed syndrome with the combination treatment of pregabalin and duloxetine.
    Journal of pain and symptom management, 2009, Volume: 38, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Leiomyoma; Pain; Pregabalin; Selective Serotonin Reuptake Inhibitors; Skin Neoplasms; Thiophenes

2009
The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trials.
    Journal of anxiety disorders, 2009, Volume: 23, Issue:8

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Secondary Prevention; Somatoform Disorders; Thiophenes; Treatment Outcome

2009
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
    Brain research, 2009, Oct-27, Volume: 1295

    Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes

2009
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Escape Reaction; Fluoxetine; Inflammation; Male; Motor Activity; Neuropsychological Tests; Pain; Pain Measurement; Physical Stimulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Scopolamine; Sulfonamides; Thiophenes; Treatment Outcome

2010
What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine.
    The Journal of rheumatology, 2009, Volume: 36, Issue:11

    Topics: Antidepressive Agents; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Thiophenes

2009
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats.
    Neuroscience research, 2010, Volume: 66, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Analgesics; Analysis of Variance; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electroshock; Formaldehyde; gamma-Aminobutyric Acid; Male; Milnacipran; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thiophenes; Vocalization, Animal

2010
Duloxetine in treating medically unexplained pain and Raynaud's phenomenon.
    The Journal of neuropsychiatry and clinical neurosciences, 2009,Fall, Volume: 21, Issue:4

    Topics: Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Off-Label Use; Pain; Raynaud Disease; Thiophenes; Treatment Outcome

2009
Pharmacological treatment of fibromyalgia syndrome: new developments.
    Drugs, 2010, Volume: 70, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Calcium Channel Blockers; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Dopamine Agonists; Duloxetine Hydrochloride; Exercise; Exercise Therapy; Fatigue; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Pain Threshold; Pregabalin; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Self Care; Thiophenes; Treatment Outcome

2010
[Expel the fear of pain. Breaking of chronicity by re-learning].
    MMW Fortschritte der Medizin, 2009, Dec-10, Volume: 151, Issue:51-52

    Topics: Analgesics; Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Fear; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2009
Management of depression in the presence of pain symptoms.
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Comorbidity; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Mind-Body Relations, Metaphysical; Norepinephrine; Pain; Psychotherapy; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2010
[Focus on treatment success of depressed patients. Early and significant pain reduction improves chances for remission].
    MMW Fortschritte der Medizin, 2010, Mar-04, Volume: 152, Issue:9

    Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Long-Term Care; Pain; Thiophenes

2010
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
    Neuropharmacology, 2010, Volume: 59, Issue:3

    Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Mecamylamine; Morphine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes

2010
Effects of duloxetine treatment on brain response to painful stimulation in major depressive disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:11

    Topics: Adult; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2010
Evaluation of healthcare resource utilization and costs in employees with pain associated with diabetic peripheral neuropathy treated with pregabalin or duloxetine.
    Journal of medical economics, 2010, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Age Factors; Analgesics; Comorbidity; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Pregabalin; Sex Factors; Socioeconomic Factors; Thiophenes; Young Adult

2010
[Effective treatment of depression. Early reduction of painful concomitant symptoms increases the probability of remission].
    MMW Fortschritte der Medizin, 2010, Nov-04, Volume: 152, Issue:44

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Early Diagnosis; General Practice; Humans; Pain; Quality of Life; Somatoform Disorders; Thiophenes

2010
[Interview with Dr. Armin Spingler. Management of depression in family practice].
    MMW Fortschritte der Medizin, 2010, Nov-04, Volume: 152, Issue:44

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; General Practice; Humans; Medication Adherence; Pain; Somatoform Disorders; Thiophenes

2010
False conclusions regarding duloxetine's purported efficacy in pain among depressed patients.
    Psychiatria Danubina, 2010, Volume: 22, Issue:4

    Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2010
Duloxetine use in painful conditions.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Analgesia; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Low Back Pain; Osteoarthritis; Pain; Retrospective Studies; Thiophenes; Treatment Outcome

2011
Treatment adherence and persistence with duloxetine, venlafaxine XR, and escitalopram among patients with major depressive disorder and chronic pain-related diseases.
    Current medical research and opinion, 2011, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Algorithms; Antidepressive Agents; Chronic Disease; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dosage Forms; Duloxetine Hydrochloride; Female; Humans; Male; Medication Adherence; Middle Aged; Pain; Retrospective Studies; Somatoform Disorders; Thiophenes; Venlafaxine Hydrochloride; Young Adult

2011
Factors associated with pain medication selection among patients diagnosed with diabetic peripheral neuropathic pain: a retrospective study.
    Journal of medical economics, 2011, Volume: 14, Issue:4

    Topics: Analgesics; Comorbidity; Costs and Cost Analysis; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Socioeconomic Factors; Thiophenes; United States

2011
Predictors of pain medication selection among patients diagnosed with fibromyalgia.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:4

    Topics: Adult; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cohort Studies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Predictive Value of Tests; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes

2012
[Because depression also hurts: duloxetine can help patients return to vitality].
    MMW Fortschritte der Medizin, 2011, Apr-07, Volume: 153, Issue:14

    Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Quality of Life; Somatoform Disorders; Thiophenes

2011
Time course of improvement of different symptom clusters in patients with major depression and pain treated with duloxetine or placebo.
    Current medical research and opinion, 2012, Volume: 28, Issue:1

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome

2012
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes

2012
Tolerability aspects in duloxetine-treated patients with depression: Should one use a lower starting dose in clinical practice?
    Expert opinion on drug safety, 2012, Volume: 11, Issue:5

    Topics: Adult; Aged; Analgesics; Antidepressive Agents; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Precision Medicine; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes

2012
Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine.
    Psychiatry research, 2013, Apr-30, Volume: 206, Issue:2-3

    Topics: Adrenergic Uptake Inhibitors; Blood Pressure; Catechol O-Methyltransferase; Depressive Disorder, Major; Diastole; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine Plasma Membrane Transport Proteins; Pain; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Receptors, Dopamine; Receptors, Serotonin; Thiophenes

2013
Analgesic effects of antidepressants.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:1

    Topics: Analgesics; Antidepressive Agents; Chronic Disease; Depressive Disorder; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Pain; Review Literature as Topic; Thiophenes

2003
A word of caution about the implied role for duloxetine in pain management.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Somatoform Disorders; Thiophenes; Treatment Outcome

2003
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Duloxetine's role in the treatment of depression and associated painful physical symptoms.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:7

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2004
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
[Duloxetine reduces pain and depression].
    Krankenpflege Journal, 2004, Volume: 42, Issue:7-10

    Topics: Adrenergic Uptake Inhibitors; Analgesics; Antidepressive Agents; Depressive Disorder; Drug Approval; Duloxetine Hydrochloride; Germany; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress

2004
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain.
    Neuropharmacology, 2005, Volume: 48, Issue:2

    Topics: Acute Disease; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Citalopram; Disease Models, Animal; Duloxetine Hydrochloride; Male; Mianserin; Mirtazapine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes

2005
Duloxetine for the treatment of major depressive disorder in older patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2005
Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents.
    European journal of pain (London, England), 2007, Volume: 11, Issue:2

    Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Drug Synergism; Duloxetine Hydrochloride; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes

2007
Duloxetine for childhood depression with pain and dissociative symptoms.
    European child & adolescent psychiatry, 2006, Volume: 15, Issue:8

    Topics: Antidepressive Agents; Benzodiazepines; Child; Depressive Disorder, Major; Dissociative Disorders; Duloxetine Hydrochloride; Female; Humans; Olanzapine; Pain; Thiophenes

2006
[Physical complaints can overlap mental symptoms. Diffuse pain? Think about depression!].
    MMW Fortschritte der Medizin, 2006, Jun-08, Volume: 148, Issue:23

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depression; Diagnosis, Differential; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Recurrence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors

2006
[Duloxetin effective in depression and pain: high remission rates obtained].
    MMW Fortschritte der Medizin, 2006, Jun-08, Volume: 148, Issue:23

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Clinical Trials as Topic; Depression; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors

2006
Does duloxetine safely and effectively reduce the severity of diabetic peripheral neuropathic pain?
    Nature clinical practice. Neurology, 2006, Volume: 2, Issue:1

    Topics: Antidepressive Agents; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2006
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
    The journal of pain, 2006, Volume: 7, Issue:11

    Topics: Antidepressive Agents; Cost-Benefit Analysis; Diabetic Neuropathies; Drug Costs; Duloxetine Hydrochloride; Humans; Pain; Thiophenes

2006
Duloxetine treatment of pediatric chronic pain and co-morbid major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:1

    Topics: Abdominal Pain; Adolescent; Antidepressive Agents; Chronic Disease; Comorbidity; Crohn Disease; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Pain; Sick Role; Thiophenes

2007
Pregabalin and duloxetine for the treatment of neuropathic pain disorders.
    Journal of pain & palliative care pharmacotherapy, 2007, Volume: 21, Issue:1

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes

2007
Pharmacological validation of a model of cystitis pain in the mouse.
    Neuroscience letters, 2007, Jun-29, Volume: 421, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ketorolac; Male; Mice; Morphine; Pain; Pain Measurement; Thiophenes

2007
Duloxetine status.
    Pain medicine (Malden, Mass.), 2007, Volume: 8 Suppl 2

    Topics: Antidepressive Agents; Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Thiophenes

2007
Does pain mediate the pain interference with sleep problem in chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine.
    Journal of pain and symptom management, 2008, Volume: 36, Issue:6

    Topics: Antidepressive Agents; Chronic Disease; Comorbidity; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Thiophenes; Treatment Outcome; United States

2008