dsp 4 has been researched along with Status Epilepticus in 2 studies
DSP 4: RN given refers to parent cpd
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A lesion of the noradrenergic nucleus Locus Coeruleus (LC) converts sporadic seizures evoked by microinfusion of bicuculline into the anterior piriform cortex (APC) of rats into limbic status epilepticus (SE)." | 3.73 | Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy. ( Blandini, F; Fornai, F; Giorgi, FS; Mauceli, G; Murri, L; Paparelli, A; Ruggieri, S, 2006) |
| " In intact rats, bicuculline (a GABA-A antagonist, 118 pmol) microinfused into this area produced sporadic seizures, while in rats previously injected with DSP-4, bicuculline determined long-lasting self-sustaining status epilepticus." | 3.72 | A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus. ( Alessandrl, MG; Ferrucci, M; Fornai, F; Giorgi, FS; Lazzeri, G; Lenzi, P; Murri, L; Pizzanelli, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giorgi, FS | 2 |
| Ferrucci, M | 1 |
| Lazzeri, G | 1 |
| Pizzanelli, C | 1 |
| Lenzi, P | 1 |
| Alessandrl, MG | 1 |
| Murri, L | 2 |
| Fornai, F | 2 |
| Mauceli, G | 1 |
| Blandini, F | 1 |
| Ruggieri, S | 1 |
| Paparelli, A | 1 |
2 other studies available for dsp 4 and Status Epilepticus
| Article | Year |
|---|---|
A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus.
Topics: Animals; Benzylamines; Bicuculline; Biogenic Monoamines; Cerebellum; Dopamine beta-Hydroxylase; Drug | 2003 |
Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy.
Topics: Animals; Benzylamines; Bicuculline; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Li | 2006 |