dsp 4 and Pain
dsp 4 has been researched along with Pain in 10 studies
DSP 4: RN given refers to parent cpd
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " After 10 days, dose-response curves for tail-flick inhibition were determined for both intraperitoneal and intraventricular injections of morphine." | 1.27 | Intrathecal DSP4 selectively depletes spinal noradrenaline and attenuates morphine analgesia. ( Ji, XQ; Tsou, K; Zhong, FX, 1985) |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Jinushi, K | 1 |
| Kushikata, T | 2 |
| Kudo, T | 3 |
| Calo, G | 1 |
| Guerrini, R | 1 |
| Hirota, K | 2 |
| Cao, LF | 1 |
| Peng, XY | 1 |
| Huang, Y | 1 |
| Wang, B | 1 |
| Zhou, FM | 1 |
| Cheng, RX | 1 |
| Chen, LH | 1 |
| Luo, WF | 1 |
| Liu, T | 1 |
| Kudo, M | 1 |
| Rowley, TJ | 1 |
| Daniel, D | 1 |
| Flood, P | 1 |
| Berge, OG | 1 |
| Ogren, SO | 1 |
| Wang, Y | 1 |
| Cheng, CY | 1 |
| Wang, JY | 1 |
| Lin, JC | 1 |
| Hajòs, M | 1 |
| Engberg, G | 1 |
| Post, C | 2 |
| Arweström, E | 1 |
| Minor, BG | 2 |
| Wikberg, JE | 1 |
| Jonsson, G | 2 |
| Archer, T | 2 |
| Zhong, FX | 1 |
| Ji, XQ | 1 |
| Tsou, K | 1 |
| Mohammed, AK | 1 |
Other Studies
10 other studies available for dsp 4 and Pain
| Article | Year |
|---|---|
Central noradrenergic activity affects analgesic effect of Neuropeptide S.
Topics: Analgesics; Animals; Benzylamines; Brain; Hypothalamus; Locus Coeruleus; Male; Neurons; Norepinephri | 2018 |
Restoring Spinal Noradrenergic Inhibitory Tone Attenuates Pain Hypersensitivity in a Rat Model of Parkinson's Disease.
Topics: Animals; Benzylamines; Corpus Striatum; Disease Models, Animal; Levodopa; Male; Norepinephrine; Oxid | 2016 |
A central neuropathic pain model by DSP-4 induced lesion of noradrenergic neurons: preliminary report.
Topics: Animals; Benzylamines; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Locus Coerul | 2010 |
The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement.
Topics: Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Benzylamines; Dopamine; | 2005 |
Limited involvement of central noradrenergic pathways in morphine-induced antinociception.
Topics: Animals; Benzylamines; Desipramine; Drug Interactions; Male; Morphine; Nervous System; Norepinephrin | 1984 |
Enhanced antinociception of clonidine in spontaneously hypertensive rats involves a presynaptic noradrenergic mechanism.
Topics: Adrenergic Agents; Animals; Antihypertensive Agents; Benzylamines; Clonidine; Hypertension; In Vitro | 1998 |
Impaired escape reaction from noxious and nonnoxious heat in rats treated with the selective noradrenergic neurotoxin DSP-4.
Topics: Animals; Benzylamines; Body Temperature Regulation; Capsaicin; Escape Reaction; Hot Temperature; Loc | 1991 |
Noradrenaline depletion increases noradrenaline-induced antinociception in mice.
Topics: Animals; Benzylamines; Dopamine; Hydroxyindoleacetic Acid; Male; Mice; Neural Pathways; Norepinephri | 1985 |
Intrathecal DSP4 selectively depletes spinal noradrenaline and attenuates morphine analgesia.
Topics: Amines; Analgesics, Opioid; Animals; Benzylamines; Brain Stem; Drug Interactions; Injections, Intrav | 1985 |
5-HT agonist induced analgesia modulated by central but not peripheral noradrenaline depletion in rats.
Topics: 5,7-Dihydroxytryptamine; Animals; Benzylamines; Central Nervous System; Hydroxydopamines; Male; Meth | 1986 |