dsp 4 has been researched along with Neurodegenerative Diseases in 3 studies
DSP 4: RN given refers to parent cpd
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Paradoxically, these prodromal symptoms are indicative of a noradrenergic hyperactivity phenotype, rather than the predicted loss of norepinephrine (NE) transmission following LC damage, suggesting the engagement of complex compensatory mechanisms." | 1.91 | The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease. ( Dougherty, JD; Iannitelli, AF; Kelberman, MA; Korukonda, A; Liles, LC; Lustberg, DJ; McCann, KE; Mulvey, B; Segal, A; Sloan, SA; Weinshenker, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Iannitelli, AF | 1 |
| Kelberman, MA | 1 |
| Lustberg, DJ | 1 |
| Korukonda, A | 1 |
| McCann, KE | 1 |
| Mulvey, B | 1 |
| Segal, A | 1 |
| Liles, LC | 1 |
| Sloan, SA | 1 |
| Dougherty, JD | 1 |
| Weinshenker, D | 1 |
| Song, S | 1 |
| Wang, Q | 1 |
| Jiang, L | 1 |
| Oyarzabal, E | 1 |
| Riddick, NV | 1 |
| Wilson, B | 1 |
| Moy, SS | 1 |
| Shih, YI | 1 |
| Hong, JS | 1 |
| Pérez, V | 1 |
| Marin, C | 1 |
| Rubio, A | 1 |
| Aguilar, E | 1 |
| Barbanoj, M | 1 |
| Kulisevsky, J | 1 |
3 other studies available for dsp 4 and Neurodegenerative Diseases
| Article | Year |
|---|---|
The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease.
Topics: Animals; Female; Locus Coeruleus; Male; Mice; Neurodegenerative Diseases; Neurotoxins; Norepinephrin | 2023 |
Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
Topics: Adrenergic Neurons; Aging; Animals; Benzylamines; Brain; Disease Models, Animal; Dopaminergic Neuron | 2019 |
Effect of the additional noradrenergic neurodegeneration to 6-OHDA-lesioned rats in levodopa-induced dyskinesias and in cognitive disturbances.
Topics: Animals; Benzylamines; Cognition Disorders; Dyskinesia, Drug-Induced; Levodopa; Locus Coeruleus; Mal | 2009 |