dsp 4 has been researched along with Innate Inflammatory Response in 10 studies
DSP 4: RN given refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroinflammation is potentiated by early degeneration of the locus coeruleus noradrenergic pathway (LC-NE) commonly seen in aging-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease." | 1.46 | A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats. ( Bharani, KL; Derex, R; Granholm, AC; Ledreux, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, S | 3 |
| Tu, D | 1 |
| Meng, C | 1 |
| Liu, J | 1 |
| Wilson, B | 3 |
| Wang, Q | 3 |
| Shih, YI | 3 |
| Gao, HM | 1 |
| Hong, JS | 3 |
| Chalermpalanupap, T | 1 |
| Schroeder, JP | 1 |
| Rorabaugh, JM | 1 |
| Liles, LC | 1 |
| Lah, JJ | 1 |
| Levey, AI | 1 |
| Weinshenker, D | 1 |
| Bharani, KL | 1 |
| Derex, R | 1 |
| Granholm, AC | 1 |
| Ledreux, A | 1 |
| Jiang, L | 2 |
| Oyarzabal, EA | 1 |
| Li, Z | 1 |
| Finnell, JE | 1 |
| Moffitt, CM | 1 |
| Hesser, LA | 1 |
| Harrington, E | 1 |
| Melson, MN | 1 |
| Wood, CS | 1 |
| Wood, SK | 1 |
| Oyarzabal, E | 1 |
| Riddick, NV | 1 |
| Moy, SS | 1 |
| Jardanhazi-Kurutz, D | 1 |
| Kummer, MP | 1 |
| Terwel, D | 1 |
| Vogel, K | 1 |
| Dyrks, T | 1 |
| Thiele, A | 1 |
| Heneka, MT | 1 |
| Wenk, GL | 1 |
| McGann, K | 1 |
| Hauss-Wegrzyniak, B | 1 |
| Rosi, S | 1 |
| Pugh, PL | 1 |
| Vidgeon-Hart, MP | 1 |
| Ashmeade, T | 1 |
| Culbert, AA | 1 |
| Seymour, Z | 1 |
| Perren, MJ | 1 |
| Joyce, F | 1 |
| Bate, ST | 1 |
| Babin, A | 1 |
| Virley, DJ | 1 |
| Richardson, JC | 1 |
| Upton, N | 1 |
| Sunter, D | 1 |
| Wei, F | 1 |
| Dubner, R | 1 |
| Ren, K | 1 |
10 other studies available for dsp 4 and Innate Inflammatory Response
| Article | Year |
|---|---|
Dysfunction of the noradrenergic system drives inflammation, α-synucleinopathy, and neuronal loss in mouse colon.
Topics: Animals; Colon; Humans; Inflammation; Mice; Norepinephrine; Synucleinopathies | 2023 |
Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
Topics: Animals; Benzylamines; Cognition Disorders; Conditioning, Psychological; Fear; Female; Genes, Lethal | 2018 |
A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats.
Topics: Aging; Analysis of Variance; Animals; Astrocytes; Benzylamines; Brain-Derived Neurotrophic Factor; C | 2017 |
Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration.
Topics: Animals; Benzylamines; Brain; Disease Progression; Dopaminergic Neurons; Gliosis; Inflammation; Lipo | 2019 |
The contribution of the locus coeruleus-norepinephrine system in the emergence of defeat-induced inflammatory priming.
Topics: Adaptation, Psychological; Animals; Benzylamines; Brain; Central Amygdaloid Nucleus; Cytokines; Depr | 2019 |
Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
Topics: Adrenergic Neurons; Aging; Animals; Benzylamines; Brain; Disease Models, Animal; Dopaminergic Neuron | 2019 |
Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
Topics: Aging; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Behavior, Animal; Benzylamines; Cogniti | 2010 |
The toxicity of tumor necrosis factor-alpha upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: implications for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Basal Nucleus of Meynert; Benzylamines; Cell Count; Choline O-Acetyltran | 2003 |
Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
Topics: Amyloid beta-Protein Precursor; Animals; Benzylamines; Corpus Striatum; Drug Administration Schedule | 2007 |
Laminar-selective noradrenergic and serotoninergic modulation includes spinoparabrachial cells after inflammation.
Topics: 5,7-Dihydroxytryptamine; Animals; Benzylamines; Fluorescent Dyes; Freund's Adjuvant; Hindlimb; Image | 1999 |