dsp 4 has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 5 studies
DSP 4: RN given refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using the rat model of parkinsonism with an additional noradrenergic degeneration induced by the N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) toxin we evaluated whether the circling motor activity and dose-failure episodes induced by levodopa (L-DOPA) differ between single (6-OHDA) and double (6-OHDA + DSP-4) denervated animals challenged with a single daily dose of L-DOPA." | 1.35 | Noradrenergic modulation of the motor response induced by long-term levodopa administration in Parkinsonian rats. ( Barbanoj, M; Gich, I; Kulisevsky, J; Pérez, V; Rodríguez-Alvarez, J; Rubio, A; Sosti, V, 2009) |
| "Behaviour was evaluated by catalepsy tests and activity box." | 1.32 | Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats. ( Schmidt, WJ; Srinivasan, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faggiani, E | 1 |
| Delaville, C | 1 |
| Benazzouz, A | 1 |
| Pérez, V | 1 |
| Sosti, V | 1 |
| Rubio, A | 1 |
| Barbanoj, M | 1 |
| Gich, I | 1 |
| Rodríguez-Alvarez, J | 1 |
| Kulisevsky, J | 1 |
| Srinivasan, J | 2 |
| Schmidt, WJ | 2 |
| Thomas, B | 1 |
| von Coelln, R | 1 |
| Mandir, AS | 1 |
| Trinkaus, DB | 1 |
| Farah, MH | 1 |
| Leong Lim, K | 1 |
| Calingasan, NY | 1 |
| Flint Beal, M | 1 |
| Dawson, VL | 1 |
| Dawson, TM | 1 |
5 other studies available for dsp 4 and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
The combined depletion of monoamines alters the effectiveness of subthalamic deep brain stimulation.
Topics: Animals; Anxiety Disorders; Benzylamines; Biogenic Monoamines; Catalepsy; Corpus Striatum; Deep Brai | 2015 |
Noradrenergic modulation of the motor response induced by long-term levodopa administration in Parkinsonian rats.
Topics: Animals; Antiparkinson Agents; Benzylamines; Brain; Disease Models, Animal; Dopamine; Dose-Response | 2009 |
Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Benzylamines; Cataleps | 2003 |
Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion: effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in rats.
Topics: Animals; Antipsychotic Agents; Benzylamines; Dopamine; Locus Coeruleus; Male; Motor Activity; Neuron | 2004 |
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzylamines; Catecholamines; Cell Survival; | 2007 |