Page last updated: 2024-10-26

dsp 4 and Anxiety

dsp 4 has been researched along with Anxiety in 8 studies

DSP 4: RN given refers to parent cpd

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"The objective of the present study is to investigate the effects of single and simultaneous lesions of the noradrenergic and serotonergic pathways (NA-X, 5-HT-X and XX, respectively) by intracerebroventricular administration of selective neurotoxins N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine-HCl (DSP-4) and 5,7-dihydroxytryptamine (5,7-DHT) on anxiety-like behavior in rats."3.76Effects of single and simultaneous lesions of serotonergic and noradrenergic pathways on open-space and bright-space anxiety-like behavior in two animal models. ( Kompagne, H; Kuki, Z; Lévay, G; Markó, B; Nagy, KM; Sziray, N, 2010)
"Diazepam (0."1.29Impaired exploratory behaviour after DSP-4 treatment in rats: implications for the increased anxiety after noradrenergic denervation. ( Bradwejn, J; Harro, J; Oreland, L; Vasar, E, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sziray, N1
Kuki, Z1
Nagy, KM1
Markó, B1
Kompagne, H1
Lévay, G1
Massé, F1
Hascoët, M1
Dailly, E1
Bourin, M1
Zagrodzka, J1
Wieczorek, M1
Romaniuk, A1
Verbanac, JS1
Altman, HJ1
Dhingra, P1
Harrington, GM1
Commissaris, RL1
Harro, J2
Oreland, L1
Vasar, E1
Bradwejn, J1
Tõnissaar, M1
Eller, M1
Lapiz, MD1
Mateo, Y1
Durkin, S1
Parker, T1
Marsden, CA1
Saldívar, A1
Ríos, C1
Fernández-Guasti, A1

Other Studies

8 other studies available for dsp 4 and Anxiety

ArticleYear
Effects of single and simultaneous lesions of serotonergic and noradrenergic pathways on open-space and bright-space anxiety-like behavior in two animal models.
    Behavioural brain research, 2010, May-01, Volume: 209, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Adaptation, Physiological; Adrenergic Agents; Adrenergic Uptake Inhibitors;

2010
Effect of noradrenergic system on the anxiolytic-like effect of DOI (5-HT2A/2C agonists) in the four-plate test.
    Psychopharmacology, 2006, Volume: 183, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Anti-Anxiety Agents;

2006
Social interactions in rats: behavioral and neurochemical alterations in DSP-4-treated rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: Aggression; Animals; Anxiety; Benzylamines; Biogenic Monoamines; Brain Chemistry; Dopamine; Male; Ne

1994
Conflict behavior in Maudsley reactive and nonreactive rats: effects of noradrenergic neuronal destruction.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:2

    Topics: Animals; Anxiety; Behavior, Animal; Benzylamines; Brain; Conflict, Psychological; Emotions; Female;

1993
Impaired exploratory behaviour after DSP-4 treatment in rats: implications for the increased anxiety after noradrenergic denervation.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adrenergic Agents; Animals; Anti-Anxiety Agents; Anxiety; Benzylamines; Diazepam; Exploratory Behavi

1995
The effects of CRA 1000, a non-peptide antagonist of corticotropin-releasing factor receptor type 1, on adaptive behaviour in the rat.
    Neuropeptides, 2001, Volume: 35, Issue:2

    Topics: Animals; Anxiety; Behavior, Animal; Benzylamines; Cerebral Cortex; Denervation; Exploratory Behavior

2001
Effects of central noradrenaline depletion by the selective neurotoxin DSP-4 on the behaviour of the isolated rat in the elevated plus maze and water maze.
    Psychopharmacology, 2001, Volume: 155, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Benzylamines; Brain Chemistry; Cerebral Cortex; Hippocampus; Hyp

2001
Differential role of serotonin and noradrenaline on anxiety reduction after ejaculation in the rat.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Animals; Anxiety; Benzylamines; Ejaculation; Male; Neurotoxins; Norepinephr

1991