dsp 4 has been researched along with Alzheimer Disease in 8 studies
DSP 4: RN given refers to parent cpd
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alzheimer's disease is a common age associated neurodegenerative disorder associated with an elevated risk of seizures that may be fundamentally connected to cognitive dysfunction." | 1.46 | Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid β plaques. ( Nuñez, A; Reyes-Marin, KE, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reyes-Marin, KE | 1 |
| Nuñez, A | 1 |
| Choudhary, P | 1 |
| Pacholko, AG | 1 |
| Palaschuk, J | 1 |
| Bekar, LK | 1 |
| Wenk, GL | 1 |
| McGann, K | 1 |
| Hauss-Wegrzyniak, B | 1 |
| Rosi, S | 1 |
| Kalinin, S | 1 |
| Gavrilyuk, V | 1 |
| Polak, PE | 1 |
| Vasser, R | 1 |
| Zhao, J | 1 |
| Heneka, MT | 2 |
| Feinstein, DL | 2 |
| Puoliväli, J | 1 |
| Pradier, L | 1 |
| Riekkinen, P | 1 |
| Galea, E | 1 |
| Gavriluyk, V | 1 |
| Dumitrescu-Ozimek, L | 1 |
| Daeschner, J | 1 |
| O'Banion, MK | 1 |
| Weinberg, G | 1 |
| Klockgether, T | 1 |
| Sara, SJ | 1 |
| Dyon-Laurent, C | 1 |
| Guibert, B | 1 |
| Leviel, V | 1 |
| Santucci, AC | 1 |
| Haroutunian, V | 1 |
| Davis, KL | 1 |
8 other studies available for dsp 4 and Alzheimer Disease
| Article | Year |
|---|---|
Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid β plaques.
Topics: Alzheimer Disease; Animals; Benzylamines; Cerebral Cortex; Disease Models, Animal; Disease Susceptib | 2017 |
The locus coeruleus neurotoxin, DSP4, and/or a high sugar diet induce behavioral and biochemical alterations in wild-type mice consistent with Alzheimers related pathology.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Benzylamines; Brain; Diet; Dietary Sugars; Memory Diso | 2018 |
The toxicity of tumor necrosis factor-alpha upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: implications for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Basal Nucleus of Meynert; Benzylamines; Cell Count; Choline O-Acetyltran | 2003 |
Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Benzylamines; Brain; C | 2007 |
Impaired recovery of noradrenaline levels in apolipoprotein E-deficient mice after N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine lesion.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Apolipoproteins E; Benzylamines; Cerebellum; Choli | 2000 |
Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; | 2002 |
Noradrenergic hyperactivity after partial fornix section: role in cholinergic dependent memory performance.
Topics: Alzheimer Disease; Animals; Benzylamines; Choline O-Acetyltransferase; Hippocampus; Male; Memory; Me | 1992 |
Pharmacological alleviation of combined cholinergic/noradrenergic lesion-induced memory deficits in rats.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Benzylamines; Cholinergic Agents; Cholinergic Fibers | 1991 |