drupacine and Liver-Neoplasms

drupacine has been researched along with Liver-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for drupacine and Liver-Neoplasms

Article	Year
[Synthesis and antitumor activity of the derivatives of cephalotaxine and drupacine]. Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:12 To make full use of cephalotaxus plant resources and search for antitumor agents with higher activities and lower side effects.. The C3 hydroxy groups of the cephlotaxine and drupacine were acylated by taxol side chain and its isomers to give a series of derivatives of cephlotaxine and drupacine.. Six novel alkaloid esters were designed and synthesized. The pharmacological screening results showed that VIIIa, VIIIb, IXa and IXc exhibited significant activities on KB, HCT and Bel in vitro.. Novel alkaloid esters are worthy to be intensively studied. Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Harringtonines; Homoharringtonine; Humans; KB Cells; Liver Neoplasms; Tumor Cells, Cultured	2003

Article

Year

[Synthesis and antitumor activity of the derivatives of cephalotaxine and drupacine].

Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:12

To make full use of cephalotaxus plant resources and search for antitumor agents with higher activities and lower side effects.. The C3 hydroxy groups of the cephlotaxine and drupacine were acylated by taxol side chain and its isomers to give a series of derivatives of cephlotaxine and drupacine.. Six novel alkaloid esters were designed and synthesized. The pharmacological screening results showed that VIIIa, VIIIb, IXa and IXc exhibited significant activities on KB, HCT and Bel in vitro.. Novel alkaloid esters are worthy to be intensively studied.

Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Harringtonines; Homoharringtonine; Humans; KB Cells; Liver Neoplasms; Tumor Cells, Cultured

2003