Page last updated: 2024-10-26

droperidol and Respiratory Insufficiency

droperidol has been researched along with Respiratory Insufficiency in 11 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" Safety outcomes were adverse effects such as QTc prolongation, hypotension, respiratory depression, and dystonic reactions."2.82A systematic review of the effectiveness and safety of droperidol for pediatric agitation in acute care settings. ( Fawcett, A; Hoffmann, JA; Janssen, AC; Mudahar, S; Pergjika, A; Ramsden, SC; Walkup, JT, 2022)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Ramsden, SC1
Pergjika, A1
Janssen, AC1
Mudahar, S1
Fawcett, A1
Walkup, JT1
Hoffmann, JA1
Krenz, JR1
Medeiros, K1
Lupez, K1
Gall, O1
Adam, F1
YELNOSKY, J1
FIELD, WE1
Martel, M1
Sterzinger, A1
Miner, J1
Clinton, J1
Biros, M1
Bigo, P1
Manno, E1
Matani, A1
Franco, I1
Jorfeldt, L1
Lewis, DH1
Löfström, JB1
Post, C1
Rich, JM1
Foldes, FF1
Molnar, I1
Refsum, HE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915]314 participants (Actual)Observational2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for droperidol and Respiratory Insufficiency

ArticleYear
A systematic review of the effectiveness and safety of droperidol for pediatric agitation in acute care settings.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022, Volume: 29, Issue:12

    Topics: Adult; Child; Droperidol; Emergency Service, Hospital; Humans; Observational Studies as Topic; Prosp

2022
[Patient-controlled analgesia. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Analgesia, Patient-Controlled; Antiemetics; Droperidol; Drug Administration Routes; Drug Synergism;

2009
Neuroleptanesthesia for general surgery.
    International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3

    Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hyperte

1973

Trials

1 trial available for droperidol and Respiratory Insufficiency

ArticleYear
Management of acute undifferentiated agitation in the emergency department: a randomized double-blind trial of droperidol, ziprasidone, and midazolam.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Antipsychotic Agents; Dose-Response Relationship, Drug

2005

Other Studies

7 other studies available for droperidol and Respiratory Insufficiency

ArticleYear
Retrospective evaluation of ketamine versus droperidol on time to restraint removal in agitated emergency department patients.
    The American journal of emergency medicine, 2023, Volume: 69

    Topics: Bradycardia; Droperidol; Emergency Service, Hospital; Humans; Ketamine; Psychomotor Agitation; Respi

2023
[Recommended use of morphine in children for postoperative pain relief. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Adolescent; Age Factors; Analgesia, Patient-Controlled; Child; Child, Preschool; Dose-Response Relat

2009
A PRELIMINARY REPORT ON THE USE OF A COMBINATION OF DROPERIDOL AND FENTANYL CITRATE IN VETERINARY MEDICINE.
    American journal of veterinary research, 1964, Volume: 25

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Behavior, Animal; Benperidol; Birds; Ca

1964
[Important side-effects of naloxone as an antagonist of neuroleptoanalgesia].
    Minerva anestesiologica, 1983, Volume: 49, Issue:6

    Topics: Aged; Anesthetics; Atropine; Cardiovascular System; Colectomy; Droperidol; Drug Combinations; Female

1983
Lung uptake of lidocaine in man as influenced by anaesthesia, mepivacaine infusion or lung insufficiency.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:1

    Topics: Adult; Aged; Droperidol; Fentanyl; Humans; Indocyanine Green; Lidocaine; Lung; Mepivacaine; Middle A

1983
Biphasic respiratory depression from neurolept anesthesia.
    AANA journal, 1982, Volume: 50, Issue:5

    Topics: Adult; Droperidol; Fentanyl; Humans; Male; Naloxone; Neuroleptanalgesia; Nitrous Oxide; Respiratory

1982
Influence of simultaneous and equal increase in external dead space and tidal volume on arterial blood gases in artificially ventilated patients.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:3

    Topics: Adult; Aged; Allyl Compounds; Anesthesia, General; Blood; Carbon Dioxide; Droperidol; Fentanyl; Huma

1974