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droperidol and Psychotic Disorders

droperidol has been researched along with Psychotic Disorders in 18 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1."6.53Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016)
"When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1."2.53Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016)
"Droperidol was compared with benzodiazepines, antipsychotics and combination treatment."2.49[Droperidol for the treatment of acutely agitated patients: still an option]. ( Budiharto, L; De Fruyt, J, 2013)
" These patients require close monitoring for adverse effects with adjustment of dosing to ensure the optimal balance of risk versus benefit while the patient is acutely psychotic."1.43Polysubstance-induced relapse of schizoaffective disorder refractory to high-dose antipsychotic medications: a case report. ( Harvey, R; Kekulawala, S; Kent, M; Mostafa, S; Tucker, MG, 2016)
"Two cases of agranulocytosis occurring after addition of a butyrophenone to a course of phenothiazine treatment are reported and possible mechanisms for this interaction are discussed."1.28Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment. ( Kehoe, R; Young, A, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's2 (11.11)18.2507
2000's3 (16.67)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gottlieb, M1
Schiebout, J1
Budiharto, L1
De Fruyt, J1
Szegő, A1
Eleméry, M1
Faludi, G1
Kovács, G1
Tucker, MG1
Kekulawala, S1
Kent, M1
Mostafa, S1
Harvey, R1
Khokhar, MA1
Rathbone, J2
Thornton, SL1
Gerona, RR1
Tomaszewski, CA1
Cure, S2
Carpenter, S2
Resnick, M1
Burton, BT1
Hooper, JF2
Minter, G1
Glod, CA1
McAllister-Williams, RH1
Ferrier, IN1
Szuba, MP1
Bergman, KS1
Baxter, LR1
Guze, BH1
Reynolds, CA1
Pelletier, LR1
Young, A1
Kehoe, R1
Peutillot, JF1
Peutillot, A1
Ellison, JM1
Deberdt, R1

Reviews

5 reviews available for droperidol and Psychotic Disorders

ArticleYear
[Droperidol for the treatment of acutely agitated patients: still an option].
    Tijdschrift voor psychiatrie, 2013, Volume: 55, Issue:3

    Topics: Acute Disease; Antipsychotic Agents; Droperidol; Humans; Psychotic Disorders; Randomized Controlled

2013
Droperidol for psychosis-induced aggression or agitation.
    The Cochrane database of systematic reviews, 2016, 12-15, Volume: 12

    Topics: Acute Disease; Aggression; Antipsychotic Agents; Benzodiazepines; Droperidol; Haloperidol; Humans; M

2016
Droperidol for acute psychosis.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Acute Disease; Antipsychotic Agents; Droperidol; Humans; Psychotic Disorders; Randomized Controlled

2004
Droperidol for acute psychosis.
    The Cochrane database of systematic reviews, 2001, Issue:2

    Topics: Acute Disease; Antipsychotic Agents; Droperidol; Humans; Psychotic Disorders; Randomized Controlled

2001
Rapid tranquillisation: time for a reappraisal of options for parenteral therapy.
    The British journal of psychiatry : the journal of mental science, 2002, Volume: 180

    Topics: Acute Disease; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Clopenthixol; Death, Sudd

2002

Trials

2 trials available for droperidol and Psychotic Disorders

ArticleYear
Droperidol vs. haloperidol in the initial management of acutely agitated patients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Commitment of Mentally Ill; Danger

1984
Droperidol in the management of psychiatric emergencies.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:4

    Topics: Adult; Aged; Droperidol; Emergencies; Female; Humans; Male; Psychotic Disorders

1983

Other Studies

11 other studies available for droperidol and Psychotic Disorders

ArticleYear
What Is the Efficacy of Droperidol for the Management of Acute Psychosis-Induced Agitation?
    Annals of emergency medicine, 2018, Volume: 71, Issue:1

    Topics: Aggression; Droperidol; Humans; Psychomotor Agitation; Psychotic Disorders

2018
[Emergency psychopharmacotherapy in Hungary -- preliminary data].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2014, Volume: 16, Issue:1

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clopenthixol; Droperidol; Drug Prescript

2014
Polysubstance-induced relapse of schizoaffective disorder refractory to high-dose antipsychotic medications: a case report.
    Journal of medical case reports, 2016, Sep-06, Volume: 10, Issue:1

    Topics: Adult; Amphetamine-Related Disorders; Antipsychotic Agents; Chlorpromazine; Clopenthixol; Droperidol

2016
Psychosis from a bath salt product containing flephedrone and MDPV with serum, urine, and product quantification.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:3

    Topics: Alkaloids; Benzodioxoles; Designer Drugs; Droperidol; Humans; Insufflation; Lorazepam; Male; Propiop

2012
Major uses of psychopharmacology in the emergency department.
    Journal of emergency nursing, 1994, Volume: 20, Issue:1

    Topics: Anxiety; Benzodiazepines; Droperidol; Education, Nursing, Continuing; Emergency Nursing; Humans; Psy

1994
Safety and efficacy of high-dose droperidol in agitated patients.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2

    Topics: Acute Disease; Adult; Dose-Response Relationship, Drug; Droperidol; Female; Humans; Infusions, Intra

1992
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Respo

1989
Droperidol and acute psychosis.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Acute Disease; Droperidol; Haloperidol; Humans; Psychotic Disorders

1987
[Droleptan].
    Soins. Psychiatrie, 1985, Issue:61

    Topics: Droperidol; Humans; Psychotic Disorders

1985
Emergency treatment of acute psychosis, agitation, and anxiety.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:4

    Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran

1985
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
    Current medical research and opinion, 1973, Volume: 1, Issue:5

    Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch

1973