droperidol has been researched along with Neuroleptic Malignant Syndrome in 12 studies
Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of droperidol-induced neuroleptic malignant syndrome during anaesthesia is presented." | 7.71 | Neuroleptic malignant syndrome induced by droperidol. ( So, PC, 2001) |
| "A 60-year-old man with psychotic depression became comatose following the administration of intravenous droperidol given for post-ECT delirious agitation." | 7.67 | Coma following ECT and intravenous droperidol: case report. ( Chien, CP; Koo, JY, 1986) |
| " Eight days later, he presented with a neuroleptic malignant syndrome following an injection of droperidol." | 3.70 | Malignant hyperthermia and neuroleptic malignant syndrome in a patient during treatment for acute asthma. ( Cardinaud, JP; Favier, JC; Gbikpi-Benissan, G; Gruson, D; Hilbert, G; Portel, L, 1999) |
| "A 60-year-old man with psychotic depression became comatose following the administration of intravenous droperidol given for post-ECT delirious agitation." | 3.67 | Coma following ECT and intravenous droperidol: case report. ( Chien, CP; Koo, JY, 1986) |
| "Neuroleptic malignant syndrome is a rare complication of antipsychotic medications." | 2.39 | Neuroleptic malignant syndrome in a trauma patient. ( Burke, C; Castellano, J; Fulda, GJ, 1995) |
| "Thus, physician should consider catatonia when treating neuroleptic malignant like syndrome." | 1.36 | [Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia]. ( Miyazaki, M; Yanagawa, Y, 2010) |
| "Treatment with dantrolene sodium combined with a forced alkaline diuresis resulted in a full recovery." | 1.29 | Postoperative neuroleptic malignant syndrome. ( Matthews, EE; Shaw, A, 1995) |
| "A case of postoperative neuroleptic malignant syndrome is presented." | 1.27 | Postoperative neuroleptic malignant syndrome. A case report. ( Bristow, G; Patel, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verdoot, P | 1 |
| Constant, EL | 1 |
| Seghers, A | 1 |
| Yanagawa, Y | 1 |
| Miyazaki, M | 1 |
| Burke, C | 1 |
| Fulda, GJ | 1 |
| Castellano, J | 1 |
| Shaw, A | 1 |
| Matthews, EE | 1 |
| Ratan, DA | 1 |
| Smith, AH | 1 |
| Garrido, SM | 1 |
| Chauncey, TR | 1 |
| Portel, L | 1 |
| Hilbert, G | 1 |
| Gruson, D | 1 |
| Favier, JC | 1 |
| Gbikpi-Benissan, G | 1 |
| Cardinaud, JP | 1 |
| Edgar, J | 1 |
| So, PC | 1 |
| Bamrah, JS | 1 |
| Patel, P | 1 |
| Bristow, G | 1 |
| Koo, JY | 1 |
| Chien, CP | 1 |
1 review available for droperidol and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome in a trauma patient.
Topics: Adult; Antipsychotic Agents; Dantrolene; Droperidol; Haloperidol; Humans; Male; Multiple Trauma; Mus | 1995 |
11 other studies available for droperidol and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuropsychiatric systemic lupus erythematosus associated with neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Dibenzothiazepines; Droperidol; Female; Humans; Lupus Vasculitis, Central Nerv | 2008 |
[Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia].
Topics: Adolescent; Analgesia; Anesthesia, General; Catatonia; Diagnosis, Differential; Diazepam; Droperidol | 2010 |
Postoperative neuroleptic malignant syndrome.
Topics: Child; Dantrolene; Diuresis; Droperidol; Female; Humans; Hyponatremia; Metoclopramide; Neuroleptic M | 1995 |
Neuroleptic malignant syndrome secondary to droperidol.
Topics: Aged; Droperidol; Female; Humans; Neuroleptic Malignant Syndrome | 1993 |
Neuroleptic malignant syndrome following autologous peripheral blood stem cell transplantation.
Topics: Antipsychotic Agents; Breast Neoplasms; Droperidol; Female; Haloperidol; Hematopoietic Stem Cell Tra | 1998 |
Malignant hyperthermia and neuroleptic malignant syndrome in a patient during treatment for acute asthma.
Topics: Acute Disease; Adjuvants, Anesthesia; Adult; Anesthetics, Inhalation; Asthma; Bronchodilator Agents; | 1999 |
Droperidol-induced neuroleptic malignant syndrome.
Topics: Adult; Antipsychotic Agents; Droperidol; Female; Humans; Neuroleptic Malignant Syndrome | 1999 |
Neuroleptic malignant syndrome induced by droperidol.
Topics: Aged; Antipsychotic Agents; Droperidol; Humans; Male; Neuroleptic Malignant Syndrome | 2001 |
Neuroleptic-induced pyrexia. A benign variant.
Topics: Adult; Droperidol; Female; Humans; Lithium; Neuroleptic Malignant Syndrome; Procyclidine | 1988 |
Postoperative neuroleptic malignant syndrome. A case report.
Topics: Adult; Cryotherapy; Dantrolene; Droperidol; Humans; Male; Neuroleptic Malignant Syndrome; Postoperat | 1987 |
Coma following ECT and intravenous droperidol: case report.
Topics: Coma; Delirium; Depressive Disorder; Droperidol; Electroconvulsive Therapy; Humans; Male; Malignant | 1986 |