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droperidol and Muscle Relaxation

droperidol has been researched along with Muscle Relaxation in 5 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" In the first study, the doses (in milligrams per kilogram) of ORG9426 that caused 50% (ED50), 90% (ED90), or 95% (ED95) neuromuscular block were determined by the individual dose-response method; they were 0."2.67The neuromuscular effects of ORG9426 in patients receiving balanced anesthesia. ( Foldes, FF; Mason, MM; Nagashima, H; Nguyen, HD; Ohta, Y; Schiller, WS, 1991)
" The dose-response curve to dopamine was shifted to the right by droperidol in concentrations above 3 X 10(-5) M."1.26Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries. ( Hatano, Y; Toda, N, 1979)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appukutty, VG1
Rajendran, SK1
Krishnan, M1
Bhushnam, KV1
Mallika, T1
Kurka, P1
Toda, N1
Hatano, Y1
Gyermek, L1
Henderson, G1
Foldes, FF1
Nagashima, H1
Nguyen, HD1
Schiller, WS1
Mason, MM1
Ohta, Y1

Trials

1 trial available for droperidol and Muscle Relaxation

ArticleYear
The neuromuscular effects of ORG9426 in patients receiving balanced anesthesia.
    Anesthesiology, 1991, Volume: 75, Issue:2

    Topics: Adult; Aged; Androstanols; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Droperidol; Fe

1991

Other Studies

4 other studies available for droperidol and Muscle Relaxation

ArticleYear
Neuroleptanaesthesia in paediatric practice.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:4

    Topics: Anesthesia, General; Child; Droperidol; Fentanyl; Heart Rate; Humans; Infant; Muscle Relaxation; Pos

1981
[Clinical experience with flunitrazepam combination anesthesia].
    Klinische Anasthesiologie und Intensivtherapie, 1978, Issue:17

    Topics: Anesthesia; Anti-Anxiety Agents; Barbiturates; Droperidol; Drug Combinations; Drug Interactions; Ele

1978
Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries.
    European journal of pharmacology, 1979, Aug-01, Volume: 57, Issue:2-3

    Topics: Animals; Coronary Vessels; Dogs; Dopamine; Dopamine Antagonists; Droperidol; Drug Interactions; Fema

1979
Electromyographic monitoring of profound surgical muscle relaxation during cardiac anesthesia.
    Journal of clinical monitoring, 1992, Volume: 8, Issue:2

    Topics: Anesthesia, General; Anesthetics; Cardiac Surgical Procedures; Diazepam; Droperidol; Electric Stimul

1992