droperidol has been researched along with Muscle Contraction in 22 studies
Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Droperidol attenuates airway smooth muscle contraction." | 3.72 | Droperidol attenuates contractile and phosphatidylinositol responses of rat trachea. ( Makita, T; Morooka, H; Saito, M; Shibata, O; Sumikawa, K, 2003) |
| "Droperidol caused no increase in twitch, but it depressed the twitch by 50% at concentrations of 9." | 1.27 | Myoneural effects of pethidine and droperidol. ( Boros, M; Chaudhry, IA; Duncalf, RM; Foldes, FF; Nagashima, H; Sherman, EH, 1984) |
| "Droperidol has no significant effects with the exception of a light increase of frequency in high doses." | 1.27 | [Spontaneous motility of the human taenia coli under morphine, thiopental and dehydrobenzperidol]. ( Bruch, HP; Gaertner, T; Rothhammer, A; Schmidt, E; Weis, KH, 1983) |
| "Cycloheximide treatment significantly reduced the increase of the inhibitory response induced by droperidol, indicating that the biosynthesis and the release of endogenous opioid are increased by droperidol." | 1.27 | Effects of droperidol on the biosynthesis and release of endogenous opioid peptides in guinea-pig ileum. ( Martinez, JA; Milanes, MV; Vargas, ML, 1987) |
| "In aortic strips, the dose-response curves for phenylephrine were obtained before and after addition of droperidol." | 1.26 | Droperidol, its alpha-adrenergic blocking action on the aortic strip and inhibitory action on norepinephrine uptake of the adrenergic terminal of the left atrial strip of rabbit. ( Kasama, A; Kaya, K; Satoh, M; Yamanaka, I; Yanagisawa, M, 1978) |
| " The dose-response curve to dopamine was shifted to the right by droperidol in concentrations above 3 X 10(-5) M." | 1.26 | Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries. ( Hatano, Y; Toda, N, 1979) |
| "Pre-treatment with reserpine reduced the potency of morphine in depressing twitches of the preparation." | 1.25 | Catecholamines and the actions of morphine on the guinea-pig ileum. ( Heimanes, RL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shibata, O | 1 |
| Saito, M | 1 |
| Makita, T | 1 |
| Morooka, H | 1 |
| Sumikawa, K | 1 |
| Boros, M | 1 |
| Chaudhry, IA | 1 |
| Nagashima, H | 1 |
| Duncalf, RM | 1 |
| Sherman, EH | 1 |
| Foldes, FF | 1 |
| Rothhammer, A | 1 |
| Schmidt, E | 1 |
| Bruch, HP | 1 |
| Weis, KH | 1 |
| Gaertner, T | 1 |
| Saitoh, Y | 2 |
| Kaneda, K | 1 |
| Toyooka, H | 2 |
| Amaha, K | 2 |
| Bobadilla, RA | 1 |
| Valencia, I | 1 |
| Ibarra, M | 1 |
| Castillo, EF | 1 |
| Castillo, C | 1 |
| Hong, E | 1 |
| Kirkegaard-Nielsen, H | 1 |
| Toft, P | 1 |
| Severinsen, IK | 1 |
| May, O | 1 |
| Sato, T | 1 |
| Hirota, K | 1 |
| Matsuki, A | 1 |
| Zsigmond, EK | 1 |
| Rabito, SF | 1 |
| Rana, J | 1 |
| Ramzan, I | 1 |
| Baker, AB | 1 |
| van Nueten, JM | 1 |
| Reneman, RS | 1 |
| Janssen, PA | 1 |
| Satoh, M | 1 |
| Kaya, K | 1 |
| Yamanaka, I | 1 |
| Kasama, A | 1 |
| Yanagisawa, M | 1 |
| Toda, N | 1 |
| Hatano, Y | 1 |
| Krahwinkel, DJ | 1 |
| Sawyer, DC | 1 |
| Eyster, GE | 1 |
| Bender, G | 1 |
| Heimanes, RL | 1 |
| Hon, CA | 1 |
| Landers, DF | 1 |
| Platts, AA | 1 |
| Eriksson, LI | 1 |
| Lennmarken, C | 1 |
| Staun, P | 1 |
| Viby-Mogensen, J | 2 |
| Engbaek, J | 1 |
| Ostergaard, D | 1 |
| Skovgaard, LT | 1 |
| Vargas, ML | 1 |
| Martinez, JA | 1 |
| Milanes, MV | 1 |
| Romero-Salinas, G | 1 |
| Pérez-Tamayo, L | 1 |
| Ruiz-Velasco, V | 1 |
| Moreno-Martínez, O | 1 |
| Bravo-Sandoval, J | 1 |
| Cruz-Montes, G | 1 |
| Sokoll, MD | 1 |
| Gergis, SD | 1 |
| Post, EL | 1 |
| Cronnelly, R | 1 |
| Long, JP | 1 |
| Kania, BF | 1 |
| Teuchmann, JK | 1 |
| Oliver, JE | 1 |
| Young, WO | 1 |
4 trials available for droperidol and Muscle Contraction
| Article | Year |
|---|---|
Post-tetanic count and single twitch height at the onset of reflex movement after administration of vecuronium under different types of anaesthesia.
Topics: Adult; Anesthesia, Inhalation; Droperidol; Female; Fentanyl; Humans; Male; Muscle Contraction; Neuro | 1994 |
Recoveries of post-tetanic twitch and train-of-four responses after administration of vecuronium with different inhalation anaesthetics and neuroleptanaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Inhalation; Droperidol; Elec | 1993 |
Optimum time for neostigmine administration to antagonize vecuronium-induced neuromuscular blockade.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Cholinesterase Inhibitors; Droperidol; | 1995 |
Use of post-tetanic count in assessment of a repetitive vecuronium-induced neuromuscular block.
Topics: Adult; Anesthesia, General; Droperidol; Female; Fentanyl; Humans; Isoflurane; Male; Middle Aged; Mus | 1990 |
18 other studies available for droperidol and Muscle Contraction
| Article | Year |
|---|---|
Droperidol attenuates contractile and phosphatidylinositol responses of rat trachea.
Topics: Adjuvants, Anesthesia; Animals; Antiemetics; Carbachol; Cholinergic Agents; Dose-Response Relationsh | 2003 |
Myoneural effects of pethidine and droperidol.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Droperidol; Drug Interactions; Electric Stimulation; In Vi | 1984 |
[Spontaneous motility of the human taenia coli under morphine, thiopental and dehydrobenzperidol].
Topics: Colon; Droperidol; Gastrointestinal Motility; Humans; In Vitro Techniques; Morphine; Muscle Contract | 1983 |
Vasodilator and hypotensive effects of droperidol.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Decerebrate State; Droperidol; Male; Muscle Contr | 1994 |
Droperidol inhibits tracheal contraction induced by serotonin, histamine or carbachol in guinea pigs.
Topics: Anesthetics, Intravenous; Animals; Carbachol; Droperidol; Female; Guinea Pigs; Histamine; In Vitro T | 1996 |
In vitro neuromuscular effects of droperidol in rats.
Topics: Animals; Diaphragm; Dopamine Antagonists; Droperidol; In Vitro Techniques; Muscle Contraction; Muscl | 2001 |
Specific alpha-adrenoceptor blocking effect of droperidol on isolated smooth muscles.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Vessels; Droperidol; Electric Stimulation; In Vitro Tec | 1977 |
Droperidol, its alpha-adrenergic blocking action on the aortic strip and inhibitory action on norepinephrine uptake of the adrenergic terminal of the left atrial strip of rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Droperidol; Drug Interactions; Heart; Heart Atria; His | 1978 |
Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries.
Topics: Animals; Coronary Vessels; Dogs; Dopamine; Dopamine Antagonists; Droperidol; Drug Interactions; Fema | 1979 |
Cardiopulmonary effects of fentanyl-droperidol, nitrous oxide, and atropine sulfate in dogs.
Topics: Analgesia; Anesthesia; Animals; Atropine; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardiovasc | 1975 |
Catecholamines and the actions of morphine on the guinea-pig ileum.
Topics: Animals; Catecholamines; Dopamine; Droperidol; Drug Tolerance; Electric Stimulation; Female; Guinea | 1975 |
Effects of neuroleptic agents on rat skeletal muscle contracture in vitro.
Topics: Animals; Antipsychotic Agents; Diaphragm; Droperidol; Drug Synergism; Haloperidol; Halothane; In Vit | 1991 |
Clinical recovery and train-of-four ratio measured mechanically and electromyographically following atracurium.
Topics: Adult; Aged; Anesthesia Recovery Period; Atracurium; Diazepam; Droperidol; Electromyography; Female; | 1989 |
Effects of droperidol on the biosynthesis and release of endogenous opioid peptides in guinea-pig ileum.
Topics: Animals; Cycloheximide; Droperidol; Endorphins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Mal | 1987 |
[Dehydrobenzperidol and its effect on the contractility of the nonpregnant human uterus. Preliminary report].
Topics: Adrenergic alpha-Antagonists; Droperidol; Evaluation Studies as Topic; Female; Humans; Injections, I | 1973 |
Effects of droperidol on neuromuscular transmission and muscle membrane.
Topics: Acetylcholine; Action Potentials; Animals; Cell Membrane; Dose-Response Relationship, Drug; Droperid | 1974 |
[Studies on the peripheral action of chlorpromazine, reserpine, dehydrobenzperidol, azacyclonol, hydroxyzine, and xylazine].
Topics: Aniline Compounds; Animals; Chlorpromazine; Droperidol; Hydroxyzine; Muscle Contraction; Muscles; Pi | 1972 |
Evaluation of pharmacologic agents for restraint in cystometry in the dog and cat.
Topics: Acepromazine; Air; Anesthesia; Aniline Compounds; Animals; Cats; Dogs; Droperidol; Female; Fentanyl; | 1973 |