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droperidol and Migraine Disorders

droperidol has been researched along with Migraine Disorders in 13 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Droperidol is an effective and safe option for the treatment of acute agitation, migraine, nausea, and pain for patients in the ED setting."5.05Reintegrating droperidol into emergency medicine practice. ( Brown, CS; Cabrera, D; Friend, K; Mattson, A, 2020)
"Included studies were randomized trials of a parenteral butyrophenone (droperidol, haloperidol) versus placebo or a comparator in migraine or benign headache with results available in English."4.87Are butyrophenones effective for the treatment of primary headache in the emergency department? ( Kelly, AM; Leong, LB, 2011)
"The treatment of a migraine attack can be difficult when first-line medication is unsuccessful and options for parenteral "rescue" therapy are limited."2.71Acute migraine treatment with droperidol: A randomized, double-blind, placebo-controlled trial. ( Alam, AS; Mendizabal, JE; Rothrock, JF; Silberstein, SD; Young, WB, 2003)
"Droperidol was better than placebo and at least as effective as comparator drugs such as prochlorperazine, meperidine, or olanzapine using droperidol doses of 2."2.52Droperidol for the treatment of acute migraine headaches. ( Musselman, ME; Shewmaker, J; Thomas, MC, 2015)
"More severe migraines often require parenteral medications and sometimes intravenous fluids."2.43Migraine--diagnosis and treatment. ( Joubert, J, 2005)
"Zolmitriptan nasal spray has a rapid onset of action and high efficacy."2.42The evolving management of migraine. ( Ashkenazi, A; Silberstein, SD, 2003)
"Droperidol (2."1.30Droperidol treatment of status migrainosus and refractory migraine. ( Silberstein, SD; Wang, SJ; Young, WB, 1997)
"It is a promising therapy for migraine."1.30Droperidol for acute migraine headache. ( Allegra, J; Eskin, B; Irving, C; Nashed, AH; Ostrow, A; Reischel, U; Richman, PB; Ritter, A; Szucs, P, 1999)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Mattson, A1
Friend, K1
Brown, CS1
Cabrera, D1
Gupta, S1
Oosthuizen, R1
Pulfrey, S1
Saguil, A1
Lax, JW1
Thomas, MC1
Musselman, ME1
Shewmaker, J1
Leong, LB1
Kelly, AM1
Silberstein, SD3
Young, WB2
Mendizabal, JE1
Rothrock, JF2
Alam, AS1
Ashkenazi, A1
Ehrenberg, BL1
Joubert, J1
Wang, SJ1
Richman, PB2
Reischel, U2
Ostrow, A1
Irving, C1
Ritter, A1
Allegra, J2
Eskin, B2
Szucs, P1
Nashed, AH2
Doran, J1
Kaiafas, C1

Reviews

6 reviews available for droperidol and Migraine Disorders

ArticleYear
Reintegrating droperidol into emergency medicine practice.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, 10-30, Volume: 77, Issue:22

    Topics: Dose-Response Relationship, Drug; Droperidol; Drug Labeling; Drug Monitoring; Drug Utilization; Emer

2020
Acute migraine treatment in emergency settings.
    American family physician, 2014, May-01, Volume: 89, Issue:9

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Dexamethasone;

2014
Droperidol for the treatment of acute migraine headaches.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:2

    Topics: Acute Disease; Dopamine Antagonists; Droperidol; Humans; Migraine Disorders; Randomized Controlled T

2015
Are butyrophenones effective for the treatment of primary headache in the emergency department?
    CJEM, 2011, Volume: 13, Issue:2

    Topics: Butyrophenones; Droperidol; Emergency Service, Hospital; Haloperidol; Headache; Humans; Migraine Dis

2011
The evolving management of migraine.
    Current opinion in neurology, 2003, Volume: 16, Issue:3

    Topics: Angiotensin Receptor Antagonists; Anticonvulsants; Antipsychotic Agents; Botulinum Toxins, Type A; C

2003
Migraine--diagnosis and treatment.
    Australian family physician, 2005, Volume: 34, Issue:8

    Topics: Analgesics; Behavior Therapy; Diet Therapy; Dopamine Antagonists; Droperidol; Family Practice; Human

2005

Trials

2 trials available for droperidol and Migraine Disorders

ArticleYear
Acute migraine treatment with droperidol: A randomized, double-blind, placebo-controlled trial.
    Neurology, 2003, Jan-28, Volume: 60, Issue:2

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Anxiety; Dopamine Antagonists; Dose-Response Relation

2003
A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Droperidol; F

2002

Other Studies

5 other studies available for droperidol and Migraine Disorders

ArticleYear
Treatment of acute migraine in the emergency department.
    Canadian family physician Medecin de famille canadien, 2014, Volume: 60, Issue:1

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents

2014
Acute migraine treatment with droperidol.
    Neurology, 2003, Dec-23, Volume: 61, Issue:12

    Topics: Acute Disease; Adult; Age of Onset; Akathisia, Drug-Induced; Chronic Disease; Diagnosis, Differentia

2003
Treatment of acute migraine with intravenous droperidol.
    Headache, 1997, Volume: 37, Issue:4

    Topics: Acute Disease; Child; Droperidol; Female; Humans; Migraine Disorders

1997
Droperidol treatment of status migrainosus and refractory migraine.
    Headache, 1997, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Antiemetics; Antipsychotic Agents; Droperidol; Evaluation Studies as Topic; Femal

1997
Droperidol for acute migraine headache.
    The American journal of emergency medicine, 1999, Volume: 17, Issue:4

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Analgesics; Dopamine Antagonists; Droperidol; Female;

1999