Page last updated: 2024-10-26

droperidol and Mental Disorders

droperidol has been researched along with Mental Disorders in 8 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"The authors report that, in treating approximately 12,000 patients over the past decade, they have never experienced a clinically significant adverse dysrhythmic event using droperidol to sedate severely agitated or violent patients."2.42A review of the safety and efficacy of droperidol for the rapid sedation of severely agitated and violent patients. ( Mastin, WD; Shale, CM; Shale, JH, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berna, F1
Timbolschi, ID1
Diemunsch, P1
Vidailhet, P1
Calver, L1
Drinkwater, V1
Isbister, GK2
Calver, LA1
Page, CB1
Stokes, B1
Bryant, JL1
Downes, MA1
Shale, JH1
Shale, CM1
Mastin, WD1
BOBON, J1
COLLARD, J1
PINCHARD, A1
BURY, J1
COLINET, M1
Chambers, RA1
Druss, BG1
Hameer, O1
Collin, K1
Ensom, MH1
Lomax, S1
Delaunay, J1
Guibert, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915]314 participants (Actual)Observational2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for droperidol and Mental Disorders

ArticleYear
A review of the safety and efficacy of droperidol for the rapid sedation of severely agitated and violent patients.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agents; Arrhythmias,

2003
Droperidol: efficacy and side effects in psychiatric emergencies.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:10

    Topics: Acute Disease; Animals; Antipsychotic Agents; Clinical Trials as Topic; Crisis Intervention; Dangero

1999

Trials

1 trial available for droperidol and Mental Disorders

ArticleYear
Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute behavioral disturbance: the DORM study.
    Annals of emergency medicine, 2010, Volume: 56, Issue:4

    Topics: Acute Disease; Adult; Aggression; Double-Blind Method; Droperidol; Drug Therapy, Combination; Emerge

2010

Other Studies

5 other studies available for droperidol and Mental Disorders

ArticleYear
Acute dystonia and akathisia following droperidol administration misdiagnosed as psychiatric disorders.
    Journal of anesthesia, 2013, Volume: 27, Issue:5

    Topics: Adult; Diagnostic Errors; Droperidol; Dystonia; Female; Humans; Mental Disorders; Psychomotor Agitat

2013
A prospective study of high dose sedation for rapid tranquilisation of acute behavioural disturbance in an acute mental health unit.
    BMC psychiatry, 2013, Sep-18, Volume: 13

    Topics: Adult; Droperidol; Drug Therapy, Combination; Female; Haloperidol; Humans; Hypnotics and Sedatives;

2013
[NEUROLEPTOANALGESIA IN PSYCHIATRIC THERAPY: THALAMONAL].
    Acta neurologica et psychiatrica Belgica, 1964, Volume: 64

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Benperidol; Droperidol; Fentanyl; Mental Disorde

1964
Evaluation of droperidol in the acutely agitated child or adolescent.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:9

    Topics: Adolescent; Arousal; Child; Dose-Response Relationship, Drug; Droperidol; Drug Administration Schedu

2001
[Oral droperidol in psychiatric therapy].
    Annales medico-psychologiques, 1974, Volume: 1, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Droperidol; Drug Evaluation; Drug Tolerance; Female;

1974