Page last updated: 2024-10-26

droperidol and Hypoxia

droperidol has been researched along with Hypoxia in 9 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"To test the hypothesis that dopamine accumulated in the carotid body limits hyperventilation during acclimatization to sustained hypoxia, we administered the dopamine antagonist droperidol to mice undergoing acclimatization to an inspired O2 fraction (FIo2) of 0."3.67Effect of a dopamine antagonist on ventilation during sustained hypoxia in mice. ( Olson, LG; Saunders, NA, 1987)
"Droperidol caused an increase in the slope of the hypoxia-induced ventilatory response from 0."1.27Stimulation of hypoxic ventilatory drive by droperidol. ( Ward, DS, 1984)
"In the awake state, arterial hypoxemia is counteracted by a mechanism which tends to normalize the ventilation/perfusion ratio of the lungs by way of a hypoxia-induced vasoconstriction in poorly ventilated areas."1.26Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics. ( Bjertnaes, LJ, 1977)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tutunaru, AC1
Sonea, A1
Drion, P1
Serteyn, D1
Sandersen, C1
Ward, DS1
Reichelt, W1
Stütz, B1
Lübbe, N1
Oelert, H1
Bjertnaes, LJ1
Strashnov, VI1
Tuleutaev, TB1
Redden, RL1
Biery, KA1
Campbell, RL1
Olson, LG1
Saunders, NA1
Vermeire, P1
van den Bogaert, P1
Bossaert, L1
Heyndrickx, G1
van Durme, JP1
Pannier, R1
Ferrari, HA1
Gorten, RJ1
Talton, IH1
Canent, R1
Goodrich, JK1

Trials

1 trial available for droperidol and Hypoxia

ArticleYear
[Analgesic effects and hemodynamic and respiratory repercussions of the fentanyl-droperidol combination in the acute stage of myocardial infarction].
    Archives des maladies du coeur et des vaisseaux, 1973, Volume: 66, Issue:4

    Topics: Adult; Aged; Benperidol; Blood Gas Analysis; Blood Pressure; Butyrophenones; Cardiac Output; Clinica

1973

Other Studies

8 other studies available for droperidol and Hypoxia

ArticleYear
Anaesthetic induction with alfaxalone may produce hypoxemia in rabbits premedicated with fentanyl/droperidol.
    Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:6

    Topics: Adjuvants, Anesthesia; Administration, Intravenous; Anesthesia; Anesthetics; Anesthetics, Combined;

2013
Stimulation of hypoxic ventilatory drive by droperidol.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:2

    Topics: Adult; Carbon Dioxide; Dopamine; Droperidol; Humans; Hypoxia; Male; Respiration; Tidal Volume

1984
[Pharmacological modifications of right-to-left shunt in tetralogy of Fallot with a history of hypoxic attacks. Effect of dehydrobenzperidol and noradrenaline during anesthesia].
    Der Anaesthesist, 1982, Volume: 31, Issue:8

    Topics: Anesthesia, General; Blood Pressure; Child, Preschool; Droperidol; Humans; Hypoxia; Norepinephrine;

1982
Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics.
    Acta anaesthesiologica Scandinavica, 1977, Volume: 21, Issue:2

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relat

1977
[Intensive acre and resuscitation in bronchial asthma and the asthmatic state].
    Terapevticheskii arkhiv, 1975, Volume: 47, Issue:8

    Topics: Acidosis; Adolescent; Adult; Aminophylline; Anesthesia; Asthma; Critical Care; Droperidol; Ephedrine

1975
Arterial oxygen desaturation during awake endotracheal intubation.
    Anesthesia progress, 1990, Volume: 37, Issue:4

    Topics: Adult; Anesthesia, General; Blood Gas Monitoring, Transcutaneous; Carbon Dioxide; Droperidol; Female

1990
Effect of a dopamine antagonist on ventilation during sustained hypoxia in mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:3

    Topics: Animals; Dopamine Antagonists; Droperidol; Hypoxia; Kinetics; Lung; Male; Mice; Mice, Inbred Strains

1987
The action of droperidol and fentanyl on cardiac output and related hemodynamic parameters.
    Southern medical journal, 1974, Volume: 67, Issue:1

    Topics: Acidosis, Respiratory; Adult; Blood; Blood Circulation; Carbon Dioxide; Cardiac Output; Droperidol;

1974