Page last updated: 2024-10-26

droperidol and Dystonia

droperidol has been researched along with Dystonia in 12 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"We report a case of bilateral ocular deviation due to droperidol-induced acute dystonia that was initially undiagnosed."7.76[Case of acute dystonia during epidural droperidol infusion to prevent postoperative nausea and vomiting]. ( Oe, K; Serada, K; Suzuki, T; Yamada, S, 2010)
" During the last intake he developed severe dystonia following zuclopenthixol 50 mg and droperidol 10 mg i."7.69[acute dystonias in combined abuse of cocaine and neuroleptics]. ( Horwitz, EH; van Harten, PN, 1994)
"A patient developed acute dystonia following intravenous administration of metocroplamide 20 mg."5.42[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol]. ( Iwade, M; Kamata, K; Morioka, N; Nakashima, K; Ozaki, M; Takahashi, E, 2015)
"We report a case of bilateral ocular deviation due to droperidol-induced acute dystonia that was initially undiagnosed."3.76[Case of acute dystonia during epidural droperidol infusion to prevent postoperative nausea and vomiting]. ( Oe, K; Serada, K; Suzuki, T; Yamada, S, 2010)
" During the last intake he developed severe dystonia following zuclopenthixol 50 mg and droperidol 10 mg i."3.69[acute dystonias in combined abuse of cocaine and neuroleptics]. ( Horwitz, EH; van Harten, PN, 1994)
"A patient developed acute dystonia following intravenous administration of metocroplamide 20 mg."1.42[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol]. ( Iwade, M; Kamata, K; Morioka, N; Nakashima, K; Ozaki, M; Takahashi, E, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's4 (33.33)18.2507
2000's3 (25.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berna, F1
Timbolschi, ID1
Diemunsch, P1
Vidailhet, P1
Kamata, K1
Takahashi, E1
Morioka, N1
Nakashima, K1
Iwade, M1
Ozaki, M1
Yamada, S1
Suzuki, T1
Oe, K1
Serada, K1
Park, CK1
Choi, HY1
Oh, IY1
Kim, MS1
Walker, M1
Samii, A1
Knott, JC1
Taylor, DM1
Castle, DJ1
Arrowsmith, J1
Gams, RA1
Shimada, J1
Akama, Y1
Tase, C1
Okuaki, A1
Horwitz, EH1
van Harten, PN1
Khan, ZH1
Warren, J1
Thompson, P1
Prusiński, A1
Rózniecki, J1
Durko, A1
Głuszcz-Zielińska, A1
Kozubski, W1
Swatko, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oro-dispersible Olanzapine (Wafer) Versus Conventional Oral Haloperidol or Diazepam Tablets for the Management of Acute Agitation in the Accident and Emergency Department - a Multicentre Randomised Clinical Trial[NCT03246620]Phase 412 participants (Actual)Interventional2017-09-01Terminated (stopped due to The study was terminated prematurely due to difficulties in patient recruitment and associated potential for selection bias.)
Intramuscular Olanzapine Versus Haloperidol or Midazolam for the Management of Acute Agitation in the Emergency Department - a Multicentre Randomised Clinical Trial[NCT02380118]Phase 4167 participants (Actual)Interventional2014-12-31Terminated (stopped due to Primary endpoint reached based on data projection from interim analysis.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for droperidol and Dystonia

ArticleYear
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
    Annals of emergency medicine, 2006, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R

2006
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
    Annals of emergency medicine, 2006, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R

2006
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
    Annals of emergency medicine, 2006, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R

2006
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
    Annals of emergency medicine, 2006, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R

2006

Other Studies

11 other studies available for droperidol and Dystonia

ArticleYear
Acute dystonia and akathisia following droperidol administration misdiagnosed as psychiatric disorders.
    Journal of anesthesia, 2013, Volume: 27, Issue:5

    Topics: Adult; Diagnostic Errors; Droperidol; Dystonia; Female; Humans; Mental Disorders; Psychomotor Agitat

2013
[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:10

    Topics: Acute Disease; Adult; Analgesia, Patient-Controlled; Antiemetics; Droperidol; Dystonia; Female; Huma

2015
[Case of acute dystonia during epidural droperidol infusion to prevent postoperative nausea and vomiting].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:2

    Topics: Acute Disease; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics

2010
Acute dystonia by droperidol during intravenous patient-controlled analgesia in young patients.
    Journal of Korean medical science, 2002, Volume: 17, Issue:5

    Topics: Acute Disease; Adolescent; Analgesia, Patient-Controlled; Analgesics; Droperidol; Dystonia; Humans;

2002
Chronic severe dystonia after single exposure to antiemetics.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:1

    Topics: Adult; Antiemetics; Chronic Disease; Droperidol; Dystonia; Female; Humans

2006
Dystonia with droperidol therapy.
    The New England journal of medicine, 1981, Jul-23, Volume: 305, Issue:4

    Topics: Adult; Droperidol; Dystonia; Humans; Middle Aged

1981
[Problems of epidural droperidol administration].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:8

    Topics: Adult; Aged; Akathisia, Drug-Induced; Droperidol; Dystonia; Female; Humans; Injections, Epidural; Ma

1994
[acute dystonias in combined abuse of cocaine and neuroleptics].
    Nederlands tijdschrift voor geneeskunde, 1994, Nov-26, Volume: 138, Issue:48

    Topics: Adult; Antipsychotic Agents; Biperiden; Clopenthixol; Cocaine; Droperidol; Dystonia; Humans; Male; S

1994
Dystonic movements following thalamonal and alfentanil induction--a case report.
    Middle East journal of anaesthesiology, 1998, Volume: 14, Issue:4

    Topics: Alfentanil; Anesthetics, Combined; Droperidol; Dystonia; Female; Fentanyl; Humans; Middle Aged; Narc

1998
Drug-induced supraglottic dystonia and spasmodic dysphonia.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:6

    Topics: Aged; Antiemetics; Basal Ganglia Diseases; Droperidol; Dystonia; Female; Humans; Metoclopramide; Tri

1998
[Acute dystonic reactions after administration of neuroleptics and other drugs].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Mar-01, Volume: 38, Issue:5

    Topics: Acute Disease; Adult; Child; Droperidol; Dystonia; Female; Humans; Male; Metoclopramide; Middle Aged

1985