droperidol has been researched along with Death, Sudden, Cardiac in 7 studies
Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Droperidol has been an efficacious, inexpensive butyrophenone used since the early 1970s to prevent or treat postoperative nausea and vomiting." | 4.82 | Haloperidol: an alternative butyrophenone for nausea and vomiting prophylaxis in anesthesia. ( Smith, JC; Wright, EL, 2005) |
| "Droperidol is a butyrophenone commonly used as an antiemetic and antipsychotic in the United States since US Food and Drug Administration (FDA) approval in 1970." | 2.42 | Droperidol, QT prolongation, and sudden death: what is the evidence? ( Evers, SJ; Kao, LW; Kirk, MA; Rosenfeld, SH, 2003) |
| "Droperidol is an antipsychotic and antiemetic drug that has been used extensively by emergency physicians, psychiatrists, and anesthesiologists worldwide since 1967." | 2.42 | Droperidol in the emergency department: is it safe? ( Richards, JR; Schneir, AB, 2003) |
| "The authors report that, in treating approximately 12,000 patients over the past decade, they have never experienced a clinically significant adverse dysrhythmic event using droperidol to sedate severely agitated or violent patients." | 2.42 | A review of the safety and efficacy of droperidol for the rapid sedation of severely agitated and violent patients. ( Mastin, WD; Shale, CM; Shale, JH, 2003) |
| "Droperidol has commonly been used to sedate extremely agitated patients in the emergency department and psychiatric settings." | 1.32 | Association between droperidol use and sudden death in two patients intoxicated with illicit stimulant drugs. ( Bradley, KG; Cox, RD; Koelliker, DE, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kao, LW | 1 |
| Kirk, MA | 1 |
| Evers, SJ | 1 |
| Rosenfeld, SH | 1 |
| Richards, JR | 1 |
| Schneir, AB | 1 |
| Shale, JH | 1 |
| Shale, CM | 1 |
| Mastin, WD | 1 |
| Gómez-Arnau, JI | 1 |
| Cox, RD | 1 |
| Koelliker, DE | 1 |
| Bradley, KG | 1 |
| Smith, JC | 1 |
| Wright, EL | 1 |
| Young, D | 1 |
4 reviews available for droperidol and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Droperidol, QT prolongation, and sudden death: what is the evidence?
Topics: Adverse Drug Reaction Reporting Systems; Antiemetics; Antipsychotic Agents; Causality; Death, Sudden | 2003 |
Droperidol in the emergency department: is it safe?
Topics: Antiemetics; Antipsychotic Agents; Death, Sudden, Cardiac; Droperidol; Drug Labeling; Emergency Trea | 2003 |
A review of the safety and efficacy of droperidol for the rapid sedation of severely agitated and violent patients.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agents; Arrhythmias, | 2003 |
Haloperidol: an alternative butyrophenone for nausea and vomiting prophylaxis in anesthesia.
Topics: Antiemetics; Butyrophenones; Death, Sudden, Cardiac; Droperidol; Haloperidol; Humans; Postoperative | 2005 |
3 other studies available for droperidol and Death, Sudden, Cardiac
| Article | Year |
|---|---|
[Droperidol and cardiac arrhythmias].
Topics: Adjuvants, Anesthesia; Antiemetics; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Droper | 2003 |
Association between droperidol use and sudden death in two patients intoxicated with illicit stimulant drugs.
Topics: Adult; Antipsychotic Agents; Death, Sudden, Cardiac; Diagnosis, Differential; Droperidol; Emergency | 2004 |
Black-box warning for droperidol surprises pharmacists.
Topics: Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Droperidol; Drug Labeling; Formularies, H | 2002 |