Page last updated: 2024-10-26

droperidol and Chronic Disease

droperidol has been researched along with Chronic Disease in 7 studies

Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Ketamine has been shown to have a morphine-sparing effect soon after surgery."2.74The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study. ( Baud, A; Couvret, C; Favard, L; Fusciardi, J; Laffon, M; Le Tendre, C; Pourrat, X; Remérand, F, 2009)
"However in the acute postoperative pain group other factors such as depletion of endorphins by drugs used for anesthesia or due to surgical stress cannot be excluded."1.26[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients]. ( Laorden, ML; Miralles, F; Olaso, MJ; Puig, MM, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Remérand, F1
Le Tendre, C1
Baud, A1
Couvret, C1
Pourrat, X1
Favard, L1
Laffon, M1
Fusciardi, J1
Goksu, S1
Kocoglu, H1
Bayazit, YA1
Yüksek, S1
Karci, Y1
Kanlikama, M1
Oner, U1
Ehrenberg, BL1
Walker, M1
Samii, A1
Laorden, ML1
Miralles, F1
Olaso, MJ1
Puig, MM1
Inoue, S1
Ninaga, H1
Kawaguchi, M1
Furuya, H1
Touho, H1
Karasawa, J1
Bach, V1
Carl, P1
Ravlo, O1
Crawford, ME1
Werner, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301]Phase 40 participants (Actual)Interventional2017-11-30Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment)
The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283]Phase 41,544 participants (Anticipated)Interventional2021-04-12Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for droperidol and Chronic Disease

ArticleYear
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:6

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana

2009
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:6

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana

2009
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:6

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana

2009
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:6

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana

2009
Antiemetic effects of granisetron, droperidol and dexamethasone in otologic surgery.
    Auris, nasus, larynx, 2002, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Chronic Disease; Dexamethasone; Double-Blind Method; Droperidol; Drug Therapy, C

2002

Other Studies

5 other studies available for droperidol and Chronic Disease

ArticleYear
Acute migraine treatment with droperidol.
    Neurology, 2003, Dec-23, Volume: 61, Issue:12

    Topics: Acute Disease; Adult; Age of Onset; Akathisia, Drug-Induced; Chronic Disease; Diagnosis, Differentia

2003
Chronic severe dystonia after single exposure to antiemetics.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:1

    Topics: Adult; Antiemetics; Chronic Disease; Droperidol; Dystonia; Female; Humans

2006
[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients].
    Revista espanola de fisiologia, 1982, Volume: 38, Issue:3

    Topics: Adult; Aged; Anesthetics; Animals; Biological Assay; Chronic Disease; Droperidol; Endorphins; Female

1982
[Anesthetic management of patients undergoing irrigation and drainage of chronic subdural hematoma--retrospective analysis of analgesia and sedation under locoregional anesthesia].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:11

    Topics: Adjuvants, Anesthesia; Age Factors; Aged; Analgesia; Anesthesia, Conduction; Anesthesia, Local; Chro

1997
Potentiation of epidural opioids with epidural droperidol. A one year retrospective study.
    Anaesthesia, 1986, Volume: 41, Issue:11

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Disease; Droperidol; Drug Synergism; Drug Therapy, Combinat

1986