droperidol has been researched along with Aggression in 10 studies
Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An assessment of the efficacy of long-term oral droperidol in the control of hyperactivity, self-mutilation, aggression and temper tantrums has been made by reference to the case history notes of sixteen mentally handicapped patients." | 7.66 | Droperidol in the management of hyperactivity, self-mutilation and aggression in mentally handicapped patients. ( Burns, ME, 1980) |
| "When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1." | 6.53 | Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016) |
| " droperidol for patients with agitation and aggression." | 5.20 | Droperidol v. haloperidol for sedation of aggressive behaviour in acute mental health: randomised controlled trial. ( Calver, L; Drinkwater, V; Gupta, R; Isbister, GK; Page, CB, 2015) |
| "An assessment of the efficacy of long-term oral droperidol in the control of hyperactivity, self-mutilation, aggression and temper tantrums has been made by reference to the case history notes of sixteen mentally handicapped patients." | 3.66 | Droperidol in the management of hyperactivity, self-mutilation and aggression in mentally handicapped patients. ( Burns, ME, 1980) |
| "When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1." | 2.53 | Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016) |
| " 4 Chronic administration of diazepam, droperidol or mescaline, all of which alter the level of aggression in different ways, can result in an inversion of the social hierarchy where a competitive rival is present in the group of mice." | 1.26 | The integrity of the social hierarchy in mice following administration of psychotropic drugs. ( Poshivalov, VP, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottlieb, M | 1 |
| Schiebout, J | 1 |
| Calver, L | 1 |
| Drinkwater, V | 1 |
| Gupta, R | 1 |
| Page, CB | 2 |
| Isbister, GK | 3 |
| Buckley, NA | 1 |
| Khokhar, MA | 1 |
| Rathbone, J | 1 |
| Calver, LA | 1 |
| Stokes, B | 1 |
| Bryant, JL | 1 |
| Downes, MA | 1 |
| Poshivalov, VP | 1 |
| Burns, ME | 1 |
| Masters, KJ | 1 |
| Thomas, H | 1 |
| Schwartz, E | 1 |
| Petrilli, R | 1 |
| Deberdt, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for droperidol and Aggression
| Article | Year |
|---|---|
Droperidol for psychosis-induced aggression or agitation.
Topics: Acute Disease; Aggression; Antipsychotic Agents; Benzodiazepines; Droperidol; Haloperidol; Humans; M | 2016 |
3 trials available for droperidol and Aggression
| Article | Year |
|---|---|
Droperidol v. haloperidol for sedation of aggressive behaviour in acute mental health: randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aggression; Antipsychotic Agents; Conscious Sedation; Droperidol; Female; H | 2015 |
Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute behavioral disturbance: the DORM study.
Topics: Acute Disease; Adult; Aggression; Double-Blind Method; Droperidol; Drug Therapy, Combination; Emerge | 2010 |
Droperidol versus haloperidol for chemical restraint of agitated and combative patients.
Topics: Adult; Aggression; Blood Pressure; Double-Blind Method; Droperidol; Emergencies; Emergency Service, | 1992 |
6 other studies available for droperidol and Aggression
| Article | Year |
|---|---|
What Is the Efficacy of Droperidol for the Management of Acute Psychosis-Induced Agitation?
Topics: Aggression; Droperidol; Humans; Psychomotor Agitation; Psychotic Disorders | 2018 |
Good clinical guidelines must define the setting, patients and evidence: Benzodiazepines versus droperidol for acute behavioural disturbance in the emergency department.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Droperidol; Emergency Service, Hospital; Humans; | 2016 |
The integrity of the social hierarchy in mice following administration of psychotropic drugs.
Topics: Aggression; Amphetamine; Animals; Diazepam; Droperidol; Hierarchy, Social; Humans; Male; Mescaline; | 1980 |
Droperidol in the management of hyperactivity, self-mutilation and aggression in mentally handicapped patients.
Topics: Administration, Oral; Adult; Aggression; Child; Droperidol; Female; Humans; Hyperkinesis; Intellectu | 1980 |
Droperidol in hospitalized children.
Topics: Aggression; Antipsychotic Agents; Behavior Therapy; Child; Child Psychiatry; Child, Hospitalized; Dr | 1998 |
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch | 1973 |