droperidol has been researched along with Acathisia, Drug-Induced in 22 studies
Droperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
droperidol : An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Akathisia, a distressing movement disorder induced by butyrophenones, has been described with low doses of droperidol used for postoperative nausea and vomiting (PONV) prophylaxis, but the incidence remains unclear." | 9.27 | Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial. ( Charton, A; Diemunsch, P; Faitot, V; Greib, N; Joshi, GP; Meyer, N; Noudem, Y; Ruimy, A, 2018) |
| "In a randomized, double-blind study, we compared the efficacy of metoclopramide hydrochloride with that of low-dose droperidol for prevention of nausea and vomiting during and after elective cesarean section with epidural anesthesia." | 9.06 | Metoclopramide versus droperidol for prevention of nausea and vomiting during epidural anesthesia for cesarean section. ( Bates, JN; Chestnut, DH; Choi, WW; Geiger, M; Ostman, PL; Owen, CL, 1989) |
| "Metoclopramide was ineffective." | 6.68 | The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995) |
| "Akathisia, a distressing movement disorder induced by butyrophenones, has been described with low doses of droperidol used for postoperative nausea and vomiting (PONV) prophylaxis, but the incidence remains unclear." | 5.27 | Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial. ( Charton, A; Diemunsch, P; Faitot, V; Greib, N; Joshi, GP; Meyer, N; Noudem, Y; Ruimy, A, 2018) |
| "In a randomized, double-blind study, we compared the efficacy of metoclopramide hydrochloride with that of low-dose droperidol for prevention of nausea and vomiting during and after elective cesarean section with epidural anesthesia." | 5.06 | Metoclopramide versus droperidol for prevention of nausea and vomiting during epidural anesthesia for cesarean section. ( Bates, JN; Chestnut, DH; Choi, WW; Geiger, M; Ostman, PL; Owen, CL, 1989) |
| "Epidural administration of droperidol has been used to prevent postoperative nausea and vomiting (PONV) caused by opioids, but the adverse reactions were relatively neglected." | 3.70 | Delayed akathisia and suicidal attempts following epidural droperidol infusion--a case report. ( Ho, YY; Hung, YC; Shen, CL, 1999) |
| "The treatment of a migraine attack can be difficult when first-line medication is unsuccessful and options for parenteral "rescue" therapy are limited." | 2.71 | Acute migraine treatment with droperidol: A randomized, double-blind, placebo-controlled trial. ( Alam, AS; Mendizabal, JE; Rothrock, JF; Silberstein, SD; Young, WB, 2003) |
| "The incidence of postoperative vomiting varied from 4." | 2.69 | The antiemetic and dysphoric effects of droperidol in the day surgery patient. ( Lim, BS; Lumsden, G; Pavy, TJ, 1999) |
| "Metoclopramide was ineffective." | 2.68 | The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995) |
| "It is a promising therapy for migraine." | 1.30 | Droperidol for acute migraine headache. ( Allegra, J; Eskin, B; Irving, C; Nashed, AH; Ostrow, A; Reischel, U; Richman, PB; Ritter, A; Szucs, P, 1999) |
| "Droperidol has both anti-emetic and neuroleptic properties and its epidural administration has been reported (Naji et al." | 1.28 | Akathisia after long-term epidural use of droperidol: a case report. ( Athanassiadis, C; Karamanis, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Charton, A | 1 |
| Greib, N | 1 |
| Ruimy, A | 1 |
| Faitot, V | 1 |
| Noudem, Y | 1 |
| Joshi, GP | 1 |
| Meyer, N | 1 |
| Diemunsch, P | 1 |
| Yap, CYL | 1 |
| Taylor, DM | 1 |
| Knott, JC | 1 |
| Taylor, SE | 1 |
| Phillips, GA | 1 |
| Karro, J | 1 |
| Chan, EW | 1 |
| Kong, DCM | 1 |
| Castle, DJ | 1 |
| Sørensen, K | 1 |
| Silberstein, SD | 1 |
| Young, WB | 1 |
| Mendizabal, JE | 1 |
| Rothrock, JF | 1 |
| Alam, AS | 1 |
| Gupta, R | 1 |
| Ehrenberg, BL | 1 |
| Weaver, CS | 1 |
| Jones, JB | 1 |
| Chisholm, CD | 1 |
| Foley, MJ | 1 |
| Giles, BK | 1 |
| Somerville, GG | 1 |
| Brizendine, EJ | 1 |
| Cordell, WH | 1 |
| Barnes, TR | 1 |
| Braude, WM | 1 |
| Hill, DJ | 1 |
| Desilva, PH | 1 |
| Darvish, AH | 1 |
| McDonald, SM | 1 |
| Cronin, MK | 1 |
| Clark, K | 1 |
| Shimada, J | 1 |
| Akama, Y | 1 |
| Tase, C | 1 |
| Okuaki, A | 1 |
| Foster, PN | 1 |
| Stickle, BR | 1 |
| Laurence, AS | 1 |
| Marsland, AR | 1 |
| Vanlint, S | 1 |
| Richman, PB | 2 |
| Reischel, U | 2 |
| Ostrow, A | 1 |
| Irving, C | 1 |
| Ritter, A | 1 |
| Allegra, J | 2 |
| Eskin, B | 2 |
| Szucs, P | 1 |
| Nashed, AH | 2 |
| Heard, K | 1 |
| Daly, FF | 1 |
| O'Malley, G | 1 |
| Rosen, N | 1 |
| Lim, BS | 1 |
| Pavy, TJ | 1 |
| Lumsden, G | 1 |
| Hung, YC | 1 |
| Ho, YY | 1 |
| Shen, CL | 1 |
| Doran, J | 1 |
| Kaiafas, C | 1 |
| Athanassiadis, C | 1 |
| Karamanis, A | 1 |
| Chestnut, DH | 1 |
| Owen, CL | 1 |
| Geiger, M | 1 |
| Bates, JN | 1 |
| Choi, WW | 1 |
| Ostman, PL | 1 |
| Ward, NG | 1 |
| Verheecke, G | 1 |
| Troch, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Etude de l'Effet du dropéridol et de l'Ondansetron Sur l'Incidence de l'Akathisie Post opératoire en Chirurgie Ambulatoire[NCT01942343] | Phase 3 | 300 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Oro-dispersible Olanzapine (Wafer) Versus Conventional Oral Haloperidol or Diazepam Tablets for the Management of Acute Agitation in the Accident and Emergency Department - a Multicentre Randomised Clinical Trial[NCT03246620] | Phase 4 | 12 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to The study was terminated prematurely due to difficulties in patient recruitment and associated potential for selection bias.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 trials available for droperidol and Acathisia, Drug-Induced
| Article | Year |
|---|---|
Incidence of akathisia after postoperative nausea and vomiting prophylaxis with droperidol and ondansetron in outpatient surgery: A multicentre controlled randomised trial.
Topics: Adult; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Antiemetics; Double-Blind Method; Dr | 2018 |
Intravenous midazolam-droperidol combination, droperidol or olanzapine monotherapy for methamphetamine-related acute agitation: subgroup analysis of a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Australia; Benzodiazepines; Dopamin | 2017 |
Acute migraine treatment with droperidol: A randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Anxiety; Dopamine Antagonists; Dose-Response Relation | 2003 |
Droperidol vs prochlorperazine for the treatment of acute headache.
Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Dopamine Antagonists; | 2004 |
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension | 1995 |
Akathisia following low-dose droperidol for antiemesis in day-case patients.
Topics: Adult; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Antiemetics; Double-Blind Method; Dr | 1996 |
The antiemetic and dysphoric effects of droperidol in the day surgery patient.
Topics: Adult; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Antiemetics; Droperidol; Female; Hum | 1999 |
A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache.
Topics: Adult; Akathisia, Drug-Induced; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Droperidol; F | 2002 |
Metoclopramide versus droperidol for prevention of nausea and vomiting during epidural anesthesia for cesarean section.
Topics: Adult; Akathisia, Drug-Induced; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Dou | 1989 |
13 other studies available for droperidol and Acathisia, Drug-Induced
| Article | Year |
|---|---|
[Dyskinesia after treatment with droperidol for preventing postoperative nausea and vomiting].
Topics: Adult; Akathisia, Drug-Induced; Antiemetics; Droperidol; Dyskinesia, Drug-Induced; Female; Humans; P | 2012 |
Akathisia can be reduced by lowering the dose of D2 receptor antagonists.
Topics: Akathisia, Drug-Induced; Dopamine Antagonists; Droperidol; Humans; Prochlorperazine | 2003 |
Acute migraine treatment with droperidol.
Topics: Acute Disease; Adult; Age of Onset; Akathisia, Drug-Induced; Chronic Disease; Diagnosis, Differentia | 2003 |
Acute akathisia after oral droperidol and metoclopramide preoperative medication.
Topics: Acute Disease; Akathisia, Drug-Induced; Droperidol; Eye Diseases; Female; Humans; Male; Metocloprami | 1982 |
[Problems of epidural droperidol administration].
Topics: Adult; Aged; Akathisia, Drug-Induced; Droperidol; Dystonia; Female; Humans; Injections, Epidural; Ma | 1994 |
Droperidol and dysphoria.
Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Droperidol; Humans; Male | 1997 |
Droperidol and dysphoria.
Topics: Akathisia, Drug-Induced; Droperidol; Humans | 1998 |
Droperidol for acute migraine headache.
Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Analgesics; Dopamine Antagonists; Droperidol; Female; | 1999 |
Respiratory distress after use of droperidol for agitation.
Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Drope | 1999 |
Delayed akathisia and suicidal attempts following epidural droperidol infusion--a case report.
Topics: Akathisia, Drug-Induced; Antiemetics; Droperidol; Female; Humans; Middle Aged; Postoperative Nausea | 1999 |
Akathisia after long-term epidural use of droperidol: a case report.
Topics: Adenocarcinoma; Aged; Akathisia, Drug-Induced; Analgesia, Epidural; Droperidol; Humans; Lung Neoplas | 1992 |
Akathisia associated with droperidol during epidural anesthesia.
Topics: Adult; Akathisia, Drug-Induced; Anesthesia, Epidural; Droperidol; Humans; Hydroxyzine; Male; Restles | 1989 |
Oral droperidol for premedication in children.
Topics: Administration, Oral; Adolescent; Akathisia, Drug-Induced; Atropine; Basal Ganglia Diseases; Child; | 1985 |