Page last updated: 2024-09-05

dronedarone and Disease Models, Animal

dronedarone has been researched along with Disease Models, Animal in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's2 (7.41)29.6817
2010's20 (74.07)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Chan, ECY; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kambayashi, R; Matsumoto, A; Nunoi, Y; Sugiyama, A; Takei, Y; Venkatesan, G1
Apicella, C; Fabritz, L; Fobian, D; Gupta, S; Holmes, AP; Kabir, SN; Kirchhof, P; Kuhlmann, SM; O'Reilly, M; O'Shea, C; Pavlovic, D; Reyat, JS; Saxena, P; Smith, GL; Syeda, F; Workman, AJ1
Hamlin, RL; Kijtawornrat, A; Limprasutr, V; Saengklub, N; Sawangkoon, S1
Ando, K; Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Lubna, NJ; Motokawa, Y; Naito, AT; Nakamura, Y; Sugiyama, A; Yamazaki, H1
Bukowska, A; Chilukoti, RK; Darm, K; Goette, A; Homuth, G; Lendeckel, J; Lendeckel, U; Peters, B; Scharf, C; Sühling, M; Utpatel, K; Völker, U; Wolke, C1
Chmielewski, J; Daniluk, J; Florek-Łuszczki, M; Karwan, S; Sawicka, KM; Wawryniuk, A; Łuszczki, JJ1
Chmielewski, J; Daniluk, J; Florek-Łuszczki, M; Karwan, S; Sawicka, KM; Wawryniuk, A; Wróblewska-Łuczka, P; Łuszczki, JJ1
Aves, T; Dorian, P; Fujii, H; Glover, BM; Hu, X; Leong-Poi, H; Ramadeen, A; Zou, L1
Breithardt, G; Eckardt, L; Frommeyer, G; Kaese, S; Kaiser, D; Milberg, P; Uphaus, T1
Belardinelli, L; Kanas, AF; Machado, AD; Nearing, BD; Pagotto, VP; Sobrado, LF; Sobrado, MF; Varone, BB; Verrier, RL; Zeng, D1
Bouitbir, J; Donzelli, M; Felser, A; Krähenbühl, S; Morand, R; Schnell, D; Stoller, A; Terracciano, L1
Bukowska, A; Evert, M; Goette, A; Kühn, JP; Lendeckel, U; Linke, J; Peters, B; Utpatel, K; Wolke, C1
Chen, KH; Du, XL; Jin, MW; Li, GR; Liu, H; Sun, HY; Wang, Y; Xiao, GS; Xu, XH; Yang, L1
Dechering, DG; Eckardt, L; Ellermann, C; Frommeyer, G; Kochhäuser, S; Leitz, P; Puckhaber, D; Reinke, F1
Goette, A; Hohnloser, S; Kirch, W; Lewalter, T; Pittrow, D1
Antzelevitch, C; Belardinelli, L; Burashnikov, A1
Antzelevitch, C; Belardinelli, L; Burashnikov, A; Di Diego, JM; Sicouri, S1
Cingolani, E; Singh, BN1
Lip, GY; Pamukcu, B1
Doerfler, A; Engelhorn, T; Heusch, G; Schulz, R; Schwarz, MA1
Bui-Xuan, B; Chevalier, P; Morel, E; Timour, Q1
Belardinelli, L; Kanas, AF; Nearing, BD; Pagotto, VP; Sobrado, MF; Verrier, RL; Zeng, D1
Agelaki, MG; Baltogiannis, GG; Fotopoulos, A; Kolettis, TM; Korantzopoulos, P; Pantos, C; Tsalikakis, DG1
Chatelain, P; Finance, O; Manning, A1
Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J1
de Groot, SH; Leunissen, JD; Molenschot, MM; Schoenmakers, M; van Der Hulst, FF; van Opstal, JM; Verduyn, SC; Vos, MA; Wellens, HJ1

Reviews

3 review(s) available for dronedarone and Disease Models, Animal

ArticleYear
[Clinical pharmacology and electrophysiological properties of dronedarone].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135 Suppl 2

    Topics: Adrenergic Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biological Availability; Calcium Channels; Disease Models, Animal; Dronedarone; Electrocardiography; Half-Life; Humans; Metabolic Clearance Rate; Sodium Channels

2010
A new agent for atrial fibrillation: electrophysiological properties of dronedarone.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4 Suppl

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Dronedarone; Electrophysiologic Techniques, Cardiac; Humans

2010
Dronedarone as a new treatment option for atrial fibrillation patients: pharmacokinetics, pharmacodynamics and clinical practice.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Disease Models, Animal; Dronedarone; Female; Heart Rate; Humans; Male

2011

Other Studies

24 other study(ies) available for dronedarone and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
An exploratory analysis of effects of poyendarone, a deuterated analogue of dronedarone, on the canine model of paroxysmal atrial fibrillation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:6

    Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Deuterium; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Dronedarone; Electrocardiography; Female; Heart Rate

2021
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone.
    Heart rhythm, 2021, Volume: 18, Issue:7

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Dronedarone; Female; Flecainide; Heart Atria; Male; Membrane Potentials; Mice; Propafenone; Sodium; Voltage-Gated Sodium Channel Blockers

2021
Dronedarone attenuates the duration of atrial fibrillation in a dog model of sustained atrial fibrillation.
    Experimental animals, 2017, Aug-05, Volume: 66, Issue:3

    Topics: Action Potentials; Administration, Oral; Amiodarone; Animals; Atrial Fibrillation; Disease Models, Animal; Dogs; Dronedarone; Heart Atria; Humans; Refractory Period, Electrophysiological; Time Factors

2017
In vivo Analysis of the Anti-atrial Fibrillatory, Proarrhythmic and Cardiodepressive Profiles of Dronedarone as a Guide for Safety Pharmacological Evaluation of Antiarrhythmic Drugs.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Output; Disease Models, Animal; Dogs; Dronedarone; Electrocardiography; Heart Conduction System; Heart Rate; Male; Refractory Period, Electrophysiological; Risk Assessment; Time Factors; Torsades de Pointes; Ventricular Function, Left; Ventricular Pressure

2018
Integration of "omics" techniques: Dronedarone affects cardiac remodeling in the infarction border zone.
    Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:11

    Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Dronedarone; Gene Expression Profiling; Immunoblotting; Microarray Analysis; Myocardial Infarction; Proteome; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Swine; Treatment Outcome; Two-Dimensional Difference Gel Electrophoresis; Ventricular Remodeling

2018
Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2019, Volume: 126, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Dronedarone; Drug Interactions; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid

2019
Dronedarone (a multichannel blocker) enhances the anticonvulsant potency of lamotrigine, but not that of lacosamide, pregabalin and topiramate in the tonic-clonic seizure model in mice.
    Epilepsy research, 2019, Volume: 154

    Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Disease Models, Animal; Dronedarone; Drug Synergism; Drug Therapy, Combination; Lacosamide; Lamotrigine; Male; Mice; Pregabalin; Seizures; Topiramate

2019
Dronedarone and Captisol-enabled amiodarone in an experimental cardiac arrest.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiopulmonary Resuscitation; Disease Models, Animal; Dronedarone; Electric Countershock; Heart Arrest; Heart Rate; Swine; Ventricular Fibrillation

2013
Antiarrhythmic effect of ranolazine in combination with class III drugs in an experimental whole-heart model of atrial fibrillation.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:6

    Topics: Acetanilides; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Dronedarone; Drug Therapy, Combination; Female; Piperazines; Rabbits; Ranolazine; Refractory Period, Electrophysiological; Sotalol

2013
Inhibition of I(f) in the atrioventricular node as a mechanism for dronedarone's reduction in ventricular rate during atrial fibrillation.
    Heart rhythm, 2013, Volume: 10, Issue:11

    Topics: Amiodarone; Animals; Atrial Fibrillation; Atrioventricular Node; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Dronedarone; Drug Therapy, Combination; Electrocardiography; Heart Rate; Heart Ventricles; Ivabradine; Male; Swine; Ventricular Function, Left

2013
Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation.
    Toxicology, 2014, Sep-02, Volume: 323

    Topics: Alanine Transaminase; Amiodarone; Animals; Anti-Arrhythmia Agents; bcl-2-Associated X Protein; Disease Models, Animal; Dronedarone; Fatty Acids; Fatty Liver; Liver; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitoylcarnitine; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger

2014
Dronedarone does not affect infarct volume as assessed by magnetic resonance imaging in a porcine model of myocardial infarction.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Biomarkers; Coronary Vessels; Disease Models, Animal; Dronedarone; Electrocardiography; Hemodynamics; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Myocardial Infarction; Swine; Ventricular Function, Left

2015
Distinctive property and pharmacology of voltage-gated sodium current in rat atrial vs ventricular myocytes.
    Heart rhythm, 2016, Volume: 13, Issue:3

    Topics: Amiodarone; Animals; Cells, Cultured; Disease Models, Animal; Dronedarone; Heart Atria; Heart Ventricles; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Sodium Channel Blockers; Voltage-Gated Sodium Channels

2016
Interactions of digitalis and class-III antiarrhythmic drugs: Amiodarone versus dronedarone.
    International journal of cardiology, 2017, Feb-01, Volume: 228

    Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Disease Models, Animal; Dronedarone; Drug Interactions; Electrocardiography; Heart Conduction System; Rabbits; Ventricular Fibrillation

2017
Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria.
    Heart rhythm, 2010, Volume: 7, Issue:9

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Dronedarone; Electrophysiologic Techniques, Cardiac; Heart Atria; Heart Conduction System; Treatment Outcome

2010
Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation.
    Journal of the American College of Cardiology, 2010, Oct-05, Volume: 56, Issue:15

    Topics: Acetanilides; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Dronedarone; Drug Synergism; Drug Therapy, Combination; Piperazines; Ranolazine

2010
Reduction of cerebral infarct size by dronedarone.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:6

    Topics: Amiodarone; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Dronedarone; Heart Rate; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Rats; Rats, Wistar; Treatment Outcome

2011
Chronic oral amiodarone but not dronedarone therapy increases ventricular defibrillation threshold during acute myocardial ischemia in a closed-chest animal model.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6

    Topics: Acute Disease; Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Coronary Occlusion; Defibrillators, Implantable; Disease Models, Animal; Dronedarone; Female; Male; Myocardial Ischemia; Swine; Ventricular Fibrillation

2012
Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial ischemia.
    Heart rhythm, 2013, Volume: 10, Issue:1

    Topics: Acetanilides; Amiodarone; Animals; Atrial Fibrillation; Chromatography, High Pressure Liquid; Disease Models, Animal; Dronedarone; Drug Therapy, Combination; Electrocardiography; Hemodynamics; Piperazines; Ranolazine; Swine; Tachycardia, Ventricular

2013
Comparative antiarrhythmic efficacy of amiodarone and dronedarone during acute myocardial infarction in rats.
    European journal of pharmacology, 2007, Jun-14, Volume: 564, Issue:1-3

    Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dronedarone; Electrocardiography, Ambulatory; Epinephrine; Female; Myocardial Infarction; Norepinephrine; Radioimmunoassay; Random Allocation; Rats; Rats, Wistar; Tachycardia, Ventricular; Telemetry; Thyroid Hormones; Ventricular Fibrillation

2007
Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, D,L-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Amiodarone; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Death, Sudden, Cardiac; Disease Models, Animal; Dronedarone; Female; Lidocaine; Male; Myocardial Ischemia; Sotalol; Stereoisomerism; Swine; Tachycardia, Ventricular; Ventricular Fibrillation

1995
SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Dronedarone; Electrocardiography; Heart Block; Heart Rate; Injections, Intravenous; Lidocaine; Myocardial Reperfusion Injury; Random Allocation; Rats; Sotalol; Ventricular Fibrillation

1995
Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome.
    Circulation, 2001, Nov-27, Volume: 104, Issue:22

    Topics: Action Potentials; Administration, Oral; Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Catheterization; Disease Models, Animal; Dogs; Dronedarone; Electrocardiography; Electrophysiologic Techniques, Cardiac; Epinephrine; Female; Heart Block; Hemodynamics; Long QT Syndrome; Male; Myocardium; Organ Size; Torsades de Pointes; Vasoconstrictor Agents; Wakefulness

2001