dronabinol has been researched along with Disease Models, Animal in 199 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (4.52) | 18.7374 |
| 1990's | 7 (3.52) | 18.2507 |
| 2000's | 67 (33.67) | 29.6817 |
| 2010's | 96 (48.24) | 24.3611 |
| 2020's | 20 (10.05) | 2.80 |
| Authors | Studies |
|---|---|
| Britch, SC; Craft, RM | 1 |
| Bagetta, G; Boccella, S; Corasaniti, MT; Gallo Afflitto, G; Guida, F; Hamamura, K; Maione, S; Nucci, C; Rombolà, L; Sakurada, S; Sakurada, T; Scuteri, D; Tonin, P; Watanabe, C | 1 |
| Brown, B; Cai, J; Cao, C; Gordon, M; Hong, Y; Li, M; Lin, X; Morgan, D; Shen, N; Wang, Y; Yan, J; Zhang, X; Zhou, Q | 1 |
| Brown, B; Cao, C; Chang, P; Fihurka, O; Gordon, MN; Hong, Y; Lin, X; Morgan, D; Shen, N; Wang, Y; Yan, J; Zhao, H; Zhou, Q | 1 |
| Casey, SL; Mitchell, VA; Sokolaj, EE; Vaughan, CW; Winters, BL | 1 |
| Baldasso, GM; Capasso, R; Cicco, P; de Assis, PM; Dutra, RC; Ferrarini, EG; Gouvêa, MC; Moreira, ELG; Paes, RS; Raposo, NRB | 1 |
| Bentulila, Z; Break, EP; David, D; Doron, R; Ellenbogen, L; Franko, M; Nitzan, K; Sarne, Y; Shamir, A; Zoharetz, M | 1 |
| Boehm, SL; Hernandez, M; Smoker, MP; Zhang, Y | 1 |
| Davis, N; Gorelick, J; Kardash, T; Kirby, M; Koman, I; Michaelevski, I; Pinhasov, A; Rodin, D | 1 |
| Cairns, EA; Kelly, MEM; Kulkarni, PM; Straiker, AJ; Szczesniak, AM; Thakur, GA; Thapa, D | 1 |
| Giuffrida, A; Martinez, AA; Seillier, A | 1 |
| Stavreva, GT; Tashev, RE; Velikova, MS | 1 |
| Acharya, C; Acharya, K; Hawkey, A; Huang, Z; Levin, ED; Lyerly, HK; Murphy, SK; Pippen, E; Rajavel, M; Schrott, R | 1 |
| Hardy, DB; Holloway, AC; Lee, K; Martínez-Peña, AA; Petrik, JJ | 1 |
| Dunford, J; Lee, AT; Morgan, MM | 1 |
| Haghparast, E; Komeili, G; Sheibani, V | 1 |
| Dahlén, A; Guo, S; Melgoza, A; Wagle, M; Zarei, M | 1 |
| Fuentes-Verdugo, E; López-Tolsa, GE; Miguéns, M; Pellón, R | 1 |
| Adelli, GR; Bhagav, P; ElSohly, MA; Gul, W; Hingorani, T; Majumdar, S; Pettaway, S; Repka, MA; Taskar, P | 1 |
| Barhum, Y; Barzilay, R; Ben-Zur, T; Gazit, N; Gil-Ad, I; Hornfeld, SH; Kamiya, A; Niwa, M; Offen, D; Sawa, A; Segal-Gavish, H; Slutsky, I; Taler, M; Weizman, A | 1 |
| Bedse, G; Gaulden, AD; Hartley, ND; Kingsley, PJ; Marnett, LJ; Neale, E; Patel, S; Patrick, TA; Plath, N; Uddin, MJ | 1 |
| King, KM; Myers, AM; Soroka-Monzo, AJ; Tallarida, RJ; Tuma, RF; Walker, EA; Ward, SJ | 1 |
| Grel, A; Metna-Laurent, M; Mondésir, M; Piazza, PV; Vallée, M | 1 |
| Cairns, BE; Hossain, S; Wong, H | 1 |
| He, X; Huang, R; Wang, M; Wang, S; Yang, L; Zhu, R; Zhuang, X | 1 |
| Appendino, G; Bellido, ML; Cantarero, I; Casano, S; Del Río, C; Ferreiro-Vera, C; Meyer, S; Morello, G; Muñoz, E; Nadal, X; Navarrete, C; Palomares, B; Sánchez-Carnerero, C | 1 |
| Atwal, N; Casey, SL; Vaughan, CW | 1 |
| Calik, MW; Carley, DW | 1 |
| Achenbach, JC; Berrue, F; Ellis, LD; Hill, J; McDougall, JJ; Morash, M | 1 |
| Henderson-Redmond, AN; LaFleur, RA; Morgan, DJ; Wilson, RP | 1 |
| Calabrese, EJ; Rubio-Casillas, A | 1 |
| Cole, M; Grant, Y; Javadi-Paydar, M; Kerr, TM; Nguyen, JD; Taffe, MA; Vandewater, SA | 1 |
| Limebeer, CL; Parker, LA; Rock, EM | 2 |
| Atwal, N; Casey, SL; Mitchell, VA; Vaughan, CW | 1 |
| Ahmad, U; Chen, X; Damaj, MI; Donvito, G; Jackson, KJ; Lichtman, AH; McIntosh, JM; Muldoon, PP; Zaveri, NT | 1 |
| Almogi-Hazan, O; Khuja, I; Or, R; Yekhtin, Z | 1 |
| Cadoni, C; Corongiu, S; Dessì, C | 1 |
| McMahon, LR; Schulze, DR; Wilkerson, JL | 1 |
| Endepols, H; Graf, R; Leweke, FM; Pahlisch, F; Rohleder, C | 1 |
| Drago, F; Drazanova, E; Kratka, L; Kuchar, M; Maryska, M; Micale, V; Ruda-Kucerova, J; Starcuk, Z; Stark, T | 1 |
| Dodick, D; Kopruszinski, CM; Navratilova, E; Patwardhan, A; Porreca, F; Swiokla, J; Vagnerova, B | 1 |
| Al-Ghezi, ZZ; Alghetaa, H; Busbee, PB; Nagarkatti, M; Nagarkatti, PS | 1 |
| Casarejos, MJ; de Yebenes, JG; Fernandez Ruiz, J; Fernandez-Estevez, M; Gomez, A; Guzman, M; Mena, MA; Muñoz, MP; Perucho, J; Sagredo, O | 1 |
| Göbel, H | 1 |
| Cron, M; Gaffal, E; Glodde, N; Tüting, T | 1 |
| Kopstick, RL; Limebeer, CL; Parker, LA; Rock, EM | 1 |
| Duncan, M; Parker, LA; Rock, EM; Sticht, MA; Stott, C | 1 |
| Calik, MW; Carley, DW; Radulovacki, M | 1 |
| Barnes, C; Bergman, J; Ferré, S; Fratta, W; Goldberg, SR; Justinova, Z; Kangas, BD; Mascia, P; Panlilio, LV; Parashos, A; Pistis, M; Redhi, GH; Scherma, M; Schwarcz, R; Secci, ME; Solinas, M; Tanda, G; Wu, HQ; Zara, T | 1 |
| Antonelli, T; Beggiato, S; Ferraro, L; Parolaro, D; Prini, P; Rubino, T; Steardo, L; Zamberletti, E | 1 |
| Altavilla, C; Cuenca, N; Esquiva, G; Lax, P | 1 |
| Bouchard, C; Gallo, A; Rompré, PP | 1 |
| Alexander, S; Burne, TH; Eyles, DW; McGrath, JJ; Turner, KM | 1 |
| Ginovart, N; Tournier, BB | 1 |
| Cornett, BL; Deng, L; Guindon, J; Hohmann, AG; Mackie, K; Makriyannis, A | 1 |
| Fishbein-Kaminietsky, M; Gafni, M; Sarne, Y | 1 |
| Bouchard, C; Ducrot, C; Fortier, E; Gallo, A; Rompré, PP | 1 |
| Burkhardt, H; Ehrenreich, H; Gerardy-Schahn, R; Hildebrandt, H; Jatho, J; Kröcher, T; Papiol, S; Röckle, I; Ronnenberg, A; Tantra, M; Winkler, D | 1 |
| Crippa, JA; dos Santos, RG; Hallak, JE; Leite, JP; Zuardi, AW | 1 |
| Bashashati, M; Eno, MR; Hu, H; Keenan, CM; Mackie, K; Makriyannis, A; Nikas, SP; Sharkey, KA; Storr, MA; Straiker, A; Thakur, GA; Wager-Miller, J; Wood, JT | 1 |
| Kinden, R; Zhang, X | 1 |
| Järbe, TU; Makriyannis, A; Nikas, SP; Shukla, VG; Tai, S; Vemuri, K | 1 |
| Bertoglio, LJ; Galve-Roperh, I; Gazarini, L; Guimaraes, FS; Stern, CA; Takahashi, RN; Vanvossen, AC; Zuardi, AW | 1 |
| Carrillo-Salinas, FJ; de Lago, E; Feliú, A; Fernández-Ruiz, J; Guaza, C; Mecha, M; Moreno-Martet, M | 1 |
| Parker, LA; Rock, EM | 1 |
| Abazyan, B; Ballinger, MD; Huang, CH; Ito, K; Jaaro-Peled, H; Kamiya, A; Mackie, K; Pletnikov, MV; Saito, A; Sawa, A; Segal, H; Taniguchi, Y; Zhu, X | 1 |
| Craft, RM; Lefever, TW; Marusich, JA; Wiley, JL | 1 |
| Abalo, R; Chen, C; Fichna, J; López-Pérez, AE; Makriyannis, A; Martín-Fontelles, MI; Storr, M; Thakur, GA; Vera, G | 1 |
| France, CP; Maguire, DR | 1 |
| Gabaglio, M; Parolaro, D; Prini, P; Rubino, T; Zamberletti, E | 1 |
| Aguilar, DD; Giuffrida, A; Lodge, DJ | 1 |
| Leitl, MD; Negus, SS | 1 |
| Andrés-Benito, P; Aso, E; Carmona, M; Ferrer, I; Maldonado, R | 1 |
| Cairns, MJ; Hollins, SL; Walker, FR; Zavitsanou, K | 1 |
| Jackson, AR; Nagarkatti, M; Nagarkatti, PS; Sido, JM | 1 |
| Justinova, Z; Le Foll, B; Panlilio, LV; Trigo, JM | 1 |
| Bartalesi, B; De Cunto, G; Fineschi, S; Galeazzi, M; Garcia Gonzalez, E; Lorenzini, S; Lucattelli, M; Lungarella, G; Selvi, E | 1 |
| Echeverry-Alzate, V; Giné, E; Lopez-Moreno, JA; Perez-Castillo, A; Rodriguez de Fonseca, F; Santos, A | 1 |
| Abdel-Salam, OME; Hosny, EN; Khadrawy, YA; Sawie, HG | 1 |
| Di Forti, M; Henquet, C; Kuepper, R; Morrison, P; Murray, RM | 1 |
| Cluny, NL; Javid, FA; Naylor, RJ; Whittle, BA | 1 |
| Díaz, A; Pazos, A; Rodríguez-Gaztelumendi, A; Rojo, ML | 1 |
| Kinsey, SG; Lichtman, AH; Schlosburg, JE | 1 |
| Burstein, SH; Zurier, RB | 1 |
| Alberio, T; Braida, D; Capurro, V; Fasano, M; Guidali, C; Parolaro, D; Realini, N; Rubino, T; Sala, M; Viganò, D | 1 |
| Bernardi, G; Carrì, MT; Centonze, D; Cozzolino, M; De Chiara, V; Maccarrone, M; Mercuri, NB; Musella, A; Rossi, S | 1 |
| Bernardi, G; Cantarella, C; Cavasinni, F; Centonze, D; De Chiara, V; Furlan, R; Lo Giudice, T; Martino, G; Martorana, A; Mataluni, G; Musella, A; Muzio, L; Rossi, S | 1 |
| Nomikos, GG; Panagis, G; Vlachou, S | 1 |
| Bromley-Brits, K; Cai, F; Chen, B; He, G; Song, W; Zhang, X | 1 |
| Bevan, SA; Hill, AJ; Jones, NA; Smith, I; Stephens, GJ; Weston, SE; Whalley, BJ; Williams, CM; Williamson, EM | 1 |
| Casu, GL; Fadda, P; Lazzari, P; Marchese, G; Pani, L | 1 |
| Brett, RR; Lewis, DY | 1 |
| Arnold, JC; Chesworth, R; Karl, T; Long, LE | 1 |
| Jamontt, JM; Molleman, A; Parsons, ME; Pertwee, RG | 1 |
| Dowie, MJ; Faull, RL; Glass, M; Hannan, AJ; Howard, ML; Nicholson, LF | 1 |
| Bäckhed, F; Cani, PD; Delzenne, NM; Lambert, DM; Muccioli, GG; Naslain, D; Reigstad, CS | 1 |
| Arnold, JC; Boucher, AA; Huang, X; Hunt, GE; Karl, T; McGregor, IS; Micheau, J | 1 |
| Dowd, E; Finn, DP; Gorman, AM; Walsh, S | 1 |
| Farrimond, JA; Whalley, BJ; Williams, CM | 1 |
| Cravatt, BF; Kinsey, SG; Lichtman, AH; Long, JZ; O'Neal, ST | 1 |
| Conti, CL; Nakamura-Palacios, EM; Rodrigues, LC | 1 |
| Assaf, F; Fishbein, M; Gafni, M; Keren, O; Sarne, Y | 1 |
| Fernández-Ruiz, J; García, C; García-Arencibia, M; Palomo-Garo, C; Pertwee, R; Ramos, J | 1 |
| Conrad, DH; Lichtman, AH; O'Neal, ST; Schlosburg, JE | 1 |
| Mehrotra, N; Meibohm, B; Moore, BM; Vaddady, PK; Yates, CR; Zhang, X | 1 |
| Crouch, GJ; Evetts, MJ; McGregor, IS; Oldfield, BJ; Stefanidis, A; Verty, AN | 1 |
| Di Marzo, V | 1 |
| Fernández-Ruiz, J; Pazos, MR; Pertwee, RG; Ramos, JA; Sagredo, O; Satta, V | 1 |
| Craft, RM; Wakley, AA | 1 |
| Ali, SF; Meyer, JS; Shen, EY | 1 |
| Becker, JA; Befort, K; Darcq, E; Dembele, D; Filliol, D; Gardon, O; Kieffer, BL; Le Merrer, J | 1 |
| Bernardi, G; Castelli, M; Centonze, D; De Chiara, V; Federici, M; Gu, HH; Mercuri, NB; Motta, C; Musella, A; Napolitano, F; Romano, R; Rossi, S; Sacchetti, L; Siracusano, A; Studer, V; Usiello, A | 1 |
| Armida, M; Beggiato, S; Chiodi, V; Domenici, MR; Ferrante, A; Ferraro, L; Martire, A; Popoli, P; Potenza, RL; Tanganelli, S; Uchigashima, M; Watanabe, M | 1 |
| Akhmetshina, A; Baldi, C; Balistreri, E; Capecchi, PL; Distler, JH; Galeazzi, M; Gianchecchi, E; Gonzalez, EG; Lazzerini, PE; Lorenzini, S; Lucattelli, M; Montilli, C; Palumbo, K; Pasini, FL; Selvi, E | 1 |
| Elbatsh, MM; Kendall, DA; Marsden, CA; Moklas, MA | 1 |
| Arnold, JC; Boucher, AA; Karl, T | 1 |
| Fernández-Ruiz, J; Pertwee, RG; Sagredo, O; Satta, V; Valdeolivas, S | 1 |
| Bregman, T; Fride, E | 2 |
| Bacigaluppi, M; Bari, M; Brambilla, E; Butti, E; Cambiaghi, M; Cebrian Silla, A; Centonze, D; Comi, G; D'Adamo, P; De Ceglia, R; De Chiara, V; Garcia-Verdugo, JM; Leocani, L; Maccarrone, M; Martino, G; Musella, A; Muzio, L; Quattrini, A; Rossi, S; Teneud, L | 1 |
| Businco, F; Dessi, C; Fadda, P; Fattore, L; Fratta, W; Goldberg, SR; Pigliacampo, B; Satta, V; Scherma, M | 1 |
| Dashney, B; Limebeer, CL; O'Brien, LD; Parker, LA; Rock, EM; Segsworth, B; Wills, KL | 1 |
| Göke, B; Kramer, J; Malo, A; Michler, T; Ochs, S; Reu, S; Schäfer, C; Storr, M | 1 |
| Cao, MH; Chen, CJ; Feng, YJ; Han, T; Li, K; Li, YY; Lin, XH; Xu, J | 1 |
| Smith, PF | 1 |
| Bari, M; Battista, N; Bernardi, G; Calabresi, P; Centonze, D; Finazzi-Agrò, A; Gubellini, P; Maccarrone, M; Picconi, B | 1 |
| Abbott, L; Burton, P; Fudge, ML; Mechoulam, R; Parker, LA; Schlievert, C | 1 |
| Farraj, AK; Harkema, JR; Jan, TR; Kaminski, NE | 1 |
| Croxford, JL; Miller, SD | 1 |
| Bifulco, M; Di Marzo, V | 1 |
| Goldberg, SR; Justinova, Z; Redhi, GH; Tanda, G | 1 |
| Gai, N; Leker, RR; Mechoulam, R; Ovadia, H | 1 |
| Bizat, N; Boyer, F; Brouillet, E; Fernández-Ruiz, J; Hantraye, P; Lastres-Becker, I | 2 |
| Lavie, G; Leker, RR; Ovadia, H; Teichner, A | 1 |
| Baker, D; Constanti, A; Gibbons, S; Pryce, G; Whalley, BJ; Wilkinson, JD; Williamson, EM | 1 |
| Beckett, SR; Chapman, V; Finn, DP; Fone, KC; Kendall, DA; Madjd, A; Marsden, CA; Roe, CH | 1 |
| Abood, ME; McAllister, SD; Moore, DH; Patel, SG; Raman, C; Rizvi, G | 1 |
| Cravatt, BF; Hillard, CJ; Patel, S | 1 |
| Goldblum, JR; Rosen, M; Walsh, RM | 1 |
| Burstein, S; Zurier, RB | 1 |
| Abe, K; Egashira, N; Fujiwara, M; Hasebe, N; Hayakawa, K; Ikeda, T; Inui, K; Iwasaki, K; Mishima, K; Takamatsu, F; Yasuda, H | 1 |
| Arnaud, C; Burger, F; Frossard, JL; Karsak, M; Mach, F; Pelli, G; Staub, C; Steffens, S; Veillard, NR; Zimmer, A | 1 |
| Aslan, S; Mitchell, VA; Safaei, R; Vaughan, CW | 1 |
| Brain, C; Chen, A; Courade, JP; Dyson, A; Fox, A; Groarke, A; Loong, Y; Peacock, M; Yaqoob, M | 1 |
| Hong, S; Kliot, M; Möller, T; Stella, N; Weydt, P; Witting, A | 1 |
| Kwiatkowska, M; Mechoulam, R; Parker, LA | 1 |
| Hader, W; Yang, C; Zhang, X | 1 |
| Hall, G; Limebeer, CL; Parker, LA | 1 |
| Reinhard, C; Wolffgramm, J | 1 |
| Burstein, SH; Johnson, DR; Rossetti, RG; Stebulis, JA; Zurier, RB | 1 |
| Dar, MS; Smith, AD | 1 |
| Dehghani, F; Ghadban, C; Koch, M; Korf, HW; Kreutz, S | 1 |
| Adler, MW; Benamar, K; Eisenstein, TK; Geller, EB; Meissler, JJ; Tallarida, RJ; Yondorf, M | 1 |
| Borlongan, C; Caldwell, RB; Crandall, J; Khalifa, YM; Liou, GI; Matragoon, S; Tsai, NT | 1 |
| Crim, J; Darmani, NA; Janoyan, JJ; Ramirez, J | 1 |
| Abe, K; Egashira, N; Fujioka, M; Fujiwara, M; Hasebe, N; Hayakawa, K; Hazekawa, M; Irie, K; Iwasaki, K; Mishima, K; Nozako, M; Orito, K | 1 |
| Andersen, ML; Papale, LA; Perry, JC; Tufik, S | 1 |
| Hilber, P; Lorivel, T | 1 |
| Buettner, R; Cravatt, B; Date, R; Di Marzo, V; Gaffal, E; Karsak, M; Mechoulam, R; Petrosino, S; Rehnelt, J; Schlicker, E; Starowicz, K; Steuder, R; Tüting, T; Wang-Eckhardt, L; Werner, S; Zimmer, A | 1 |
| Mitchell, VA; Vaughan, CW; Vuong, LA | 1 |
| Bari, M; Battistini, L; Bernardi, G; Bernardini, S; Centonze, D; De Chiara, V; Fezza, F; Furlan, R; Maccarrone, M; Martino, G; Prosperetti, C; Rossi, S | 1 |
| Cannavacciulo, R; Cravatt, BF; Lichtman, AH; Martin, BF; Wise, LE | 1 |
| Guidali, C; Massi, P; Parolaro, D; Realini, N; Rubino, T; Valenti, M; Vigano, D | 1 |
| Gorzalka, BB; Hill, MN; McLaughlin, RJ; Morrish, AC | 1 |
| Braida, D; Capurro, V; Sala, M; Zani, A | 1 |
| Buchweitz, JP; Harkema, JR; Kaminski, NE; Karmaus, PW; Williams, KJ | 1 |
| Jongsma, MJ; Olivier, B; Philippens, IH; van Vliet, SA; Vanwersch, RA | 1 |
| Goldberg, SR; Justinova, Z; Munzar, P; Panlilio, LV; Redhi, GH; Tanda, G; Yasar, S | 1 |
| Berger, M; Hornyak, M; Riemann, D; Schierenbeck, T | 1 |
| Cravatt, BF; Hegde, S; Hegde, VL; Hofseth, LJ; Nagarkatti, M; Nagarkatti, PS | 1 |
| Bradley, SG; Morahan, PS | 1 |
| Hasegawa, T; Kameyama, T; Katsumata, Y; Kinoshita, H; Nabeshima, T; Yamamoto, I | 1 |
| Friedman, H; Paradise, LJ | 1 |
| Bass, R; Engelhard, D; Shohami, E; Trembovler, V | 1 |
| Abramsky, O; Leker, RR; Ovadia, H; Shohami, E | 1 |
| Limebeer, CL; Parker, LA | 1 |
| Davydova, YG; Maimeskulova, LA; Mechoulam, R; Ugdyzhekova, DS | 1 |
| Fujiwara, M | 1 |
| Fox, A; Gentry, C; James, I; Kesingland, A; McNair, K; Patel, S; Urban, L | 1 |
| Lavie, G; Leker, RR; Ovadia, H; Shohami, E; Teichner, A | 1 |
| Burstein, S; Jang, T; Karim, P; Kubiatowski, T; Litofsky, NS; Pipia, G; Recht, LD; Rosetti, R; Ross, AH; Salmonsen, R; Zurier, R | 1 |
| Piomelli, D | 1 |
| Crombag, H; De Vries, TJ; Dieben, J; Homberg, JR; Schoffelmeer, AN; Schuurman, K; Shaham, Y; Vanderschuren, LJ | 1 |
| Denhardt, G; Smith, SR; Terminelli, C | 1 |
| Colleoni, M; Conti, S; Costa, B; Giagnoni, G; Parolaro, D | 1 |
| Bradley, SG; Cabral, G; Ferguson, T; Marciano-Cabral, F | 1 |
| Mechoulam, R; Parker, LA; Schlievert, C | 1 |
| Green, K | 1 |
| Chiarotti, M; Giusti, GV; Passatore, M | 1 |
| Sassin, JF | 1 |
| Dow-Edwards, D; Hutchings, DE | 1 |
| Lyman, WD | 1 |
| Consroe, P; Mechoulam, R | 1 |
| Balster, RL; Beardsley, PM; Harris, LS | 1 |
| Adams, PM; Barratt, ES | 1 |
| de Voss, R; Lemmingson, O; Lüllmann, H; Prooter, H | 1 |
| Corcoran, ME; Sato, M; Wada, JA | 1 |
19 review(s) available for dronabinol and Disease Models, Animal
| Article | Year |
|---|---|
Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence.
Topics: Animals; Anti-Inflammatory Agents; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Evaluation, Preclinical; Eye Pain; Leukocytes; Lipid Metabolism; Rodentia; Uveitis | 2022 |
Biphasic effects of THC in memory and cognition.
Topics: Age Factors; Alzheimer Disease; Animals; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Hippocampus; Humans; Marijuana Smoking; Memory Disorders; Memory, Short-Term; Neurogenesis; Nootropic Agents; Receptor, Cannabinoid, CB1 | 2018 |
[Cannabis in medicine]].
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcotic; Animals; Cannabis; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Evaluation, Preclinical; Drug Interactions; Germany; Humans; Mice; Pain Clinics; Phytotherapy; Plant Extracts; Receptor, Cannabinoid, CB1; Self Medication | 2004 |
Phytocannabinoids and epilepsy.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Cerebral Cortex; Clinical Trials as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Evaluation, Preclinical; Endocannabinoids; Epilepsy; Humans; Phytotherapy; Plant Extracts | 2015 |
Screening Medications for the Treatment of Cannabis Use Disorder.
Topics: Animals; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Evaluation, Preclinical; Humans; Marijuana Abuse; Self Administration | 2016 |
Gene-environment interplay between cannabis and psychosis.
Topics: Alleles; Animals; Catechol O-Methyltransferase; Disease Models, Animal; Dronabinol; Epigenesis, Genetic; Gene Expression; Genotype; Humans; Individuality; Marijuana Abuse; Neuropsychological Tests; Psychiatric Status Rating Scales; Receptor, Cannabinoid, CB1; Risk Factors; Schizophrenia; Schizophrenic Psychology; Social Environment; Stress, Psychological | 2008 |
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation.
Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Disease Models, Animal; Dronabinol; Drug Delivery Systems; Drug Evaluation, Preclinical; Endocannabinoids; Glycerides; Humans; Inflammation; Mice; Mice, Knockout; Pain; Peroxisome Proliferator-Activated Receptors; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Opioid; TRPV Cation Channels | 2009 |
Cannabinoids, endocannabinoids, and related analogs in inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Cannabis; Disease Models, Animal; Dronabinol; Drug Evaluation, Preclinical; Eicosanoids; Endocannabinoids; Fibromyalgia; Glycine; Humans; Inflammation; Mice; Plant Oils; Randomized Controlled Trials as Topic; Rats; Receptors, Cannabinoid | 2009 |
Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Drug Tolerance; Endocannabinoids; Humans; Macaca mulatta; Marijuana Abuse; Mice; Motivation; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB1; Reward; Self Administration; Substance Withdrawal Syndrome; Synaptic Transmission | 2008 |
Endocannabinoid pathways and their role in multiple sclerosis-related muscular dysfunction.
Topics: Animals; Cannabidiol; Disease Models, Animal; Dronabinol; Drug Combinations; Endocannabinoids; Mice; Multiple Sclerosis; Muscle Spasticity; Muscle, Skeletal; Plant Extracts | 2011 |
Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.
Topics: Analgesics, Non-Narcotic; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cannabis; Disease Models, Animal; Dronabinol; Fatty Acids, Unsaturated; Humans; Multiple Sclerosis; Muscle Weakness; Pain; Receptors, Cannabinoid; Receptors, Drug; Spasm | 2002 |
[The endocannabinoid system as a target for the development of new drugs for cancer therapy].
Topics: Adult; Animals; Antineoplastic Agents; Apoptosis; Cannabinoid Receptor Modulators; Cannabinoids; Cell Death; Disease Models, Animal; Dronabinol; Endocannabinoids; Fatty Acids, Unsaturated; Female; Humans; Male; Mice; Neoplasms; Rats; Receptors, Cannabinoid; Receptors, Drug; Research; Tumor Cells, Cultured | 2003 |
Effect of illicit recreational drugs upon sleep: cocaine, ecstasy and marijuana.
Topics: Animals; Brain; Cocaine; Disease Models, Animal; Dronabinol; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Polysomnography; Sleep; Sleep Stages; Substance Withdrawal Syndrome; Substance-Related Disorders | 2008 |
Syphilis and drugs of abuse.
Topics: Animals; Cricetinae; Disease Models, Animal; Disease Susceptibility; Dronabinol; Humans; Illicit Drugs; Rabbits; Syphilis | 1993 |
[Characteristics of abnormal behavior induced by delta 9-tetrahydrocannabinol in rats].
Topics: Animals; Disease Models, Animal; Dronabinol; Humans; Marijuana Abuse; Mental Disorders; Mice; Rats; Receptors, Cannabinoid; Receptors, Drug; Receptors, Serotonin | 2001 |
The ocular effects of cannabinoids.
Topics: Animals; Aqueous Humor; Cannabinoids; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Ciliary Body; Cornea; Cyclooxygenase Inhibitors; Disease Models, Animal; Dronabinol; Eye; Glaucoma; Humans; In Vitro Techniques; Intraocular Pressure; Iris; Rabbits; Rats; Receptors, Adrenergic; Sympathectomy | 1979 |
Drug-induced dyskinesia in monkeys.
Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Azides; Carbachol; Caudate Nucleus; Chlorpromazine; Disease Models, Animal; Dronabinol; Hydroxydopamines; Levodopa; Movement Disorders; Phenothiazines; Primates; Stereotaxic Techniques; Substantia Nigra; Tegmentum Mesencephali | 1975 |
Animal models of opiate, cocaine, and cannabis use.
Topics: Animals; Cannabis; Cocaine; Disease Models, Animal; Dronabinol; Female; Fetus; Maternal-Fetal Exchange; Narcotics; Pregnancy; Substance-Related Disorders | 1991 |
Drugs of abuse and experimental autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Demyelinating Diseases; Disease Models, Animal; Dronabinol; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Female; Immunosuppressive Agents; Lymphocyte Activation; Male; Multiple Sclerosis; Neuritis, Autoimmune, Experimental; Polyradiculoneuropathy; Rats; Rats, Inbred Lew | 1991 |
1 trial(s) available for dronabinol and Disease Models, Animal
| Article | Year |
|---|---|
Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Administration Schedule; Drug Interactions; GABA Antagonists; Male; Maze Learning; Mice; Mice, Inbred ICR; Neuropsychological Tests; Pentylenetetrazole; Psychotropic Drugs; Reaction Time; Recognition, Psychology; Time Factors | 2011 |
179 other study(ies) available for dronabinol and Disease Models, Animal
| Article | Year |
|---|---|
No antinociceptive synergy between morphine and delta-9-tetrahydrocannabinol in male and female rats with persistent inflammatory pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Locomotion; Male; Morphine; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Sex Factors | 2021 |
Low-Dose Delta-9-Tetrahydrocannabinol as Beneficial Treatment for Aged APP/PS1 Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Dronabinol; Glycogen Synthase Kinase 3 beta; Maze Learning; Mice; Mice, Transgenic; Presenilin-1 | 2022 |
The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC.
Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Dronabinol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1 | 2022 |
Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model.
Topics: Analgesics; Animals; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoids; Cannabis; Disease Models, Animal; Dronabinol; Hallucinogens; Hyperalgesia; Mice; Neuralgia | 2022 |
Broad-spectrum cannabis oil ameliorates reserpine-induced fibromyalgia model in mice.
Topics: Analgesics; Animals; Cannabis; Disease Models, Animal; Dronabinol; Fibromyalgia; Hyperalgesia; Mice; Reserpine | 2022 |
An Ultra-Low Dose of ∆9-Tetrahydrocannabinol Alleviates Alzheimer's Disease-Related Cognitive Impairments and Modulates TrkB Receptor Expression in a 5XFAD Mouse Model.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Dronabinol; Mice; Mice, Transgenic; Receptor, trkB | 2022 |
Assessment of Acute Motor Effects and Tolerance Following Self-Administration of Alcohol and Edible ∆
Topics: Alcohol Drinking; Animals; Disease Models, Animal; Dronabinol; Drug Interactions; Drug Tolerance; Male; Marijuana Abuse; Mice; Mice, Inbred C57BL; Motor Activity; Self Administration | 2019 |
Link between personality and response to THC exposure.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Conditioning, Psychological; Corticosterone; Depression; Disease Models, Animal; Dominance-Subordination; Dronabinol; Male; Mice; Personality | 2020 |
Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation.
Topics: Allosteric Regulation; Animals; Cautery; Corneal Injuries; Disease Models, Animal; Dronabinol; Drug Synergism; Gene Knockout Techniques; Hyperalgesia; Indoles; Inflammation; Ligands; Mice; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Signal Transduction | 2020 |
Differential effects of Δ9-tetrahydrocannabinol dosing on correlates of schizophrenia in the sub-chronic PCP rat model.
Topics: Animals; Arachidonic Acids; Disease Models, Animal; Dronabinol; Endocannabinoids; Glycogen Synthase Kinase 3 beta; Male; Motor Activity; Neurons; Phencyclidine; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Schizophrenia; Signal Transduction; Ventral Tegmental Area | 2020 |
Subchronic Central Administration of Cannabinoid Ligands Modulates Nociception in Bulbectomized Rats.
Topics: Animals; Depression; Disease Models, Animal; Dronabinol; Ligands; Male; Nociception; Olfactory Bulb; Pain Threshold; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant | 2019 |
Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.
Topics: Animals; Autistic Disorder; Chromatin; CpG Islands; Disease Models, Animal; DNA Methylation; Dronabinol; Epigenesis, Genetic; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Male; Nicotine; Rats; Sequence Analysis, DNA; Spermatozoa | 2020 |
Gestational exposure to Δ
Topics: Angiogenesis Inducing Agents; Animals; Brain; Disease Models, Animal; Dronabinol; Female; Maternal Exposure; Ovarian Follicle; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2021 |
Tetrahydrocannabinol (THC) Exacerbates Inflammatory Bowel Disease in Adolescent and Adult Female Rats.
Topics: Age Factors; Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Disease Models, Animal; Dronabinol; Female; Inflammatory Bowel Diseases; Rats; Rats, Sprague-Dawley; Running; Symptom Flare Up | 2021 |
Marijuana improved motor impairments and changes in synaptic plasticity-related molecules in the striatum in 6-OHDA-treated rats.
Topics: Adrenergic Agents; Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Disease Models, Animal; Disks Large Homolog 4 Protein; Dronabinol; Dyskinesia, Drug-Induced; Male; Medical Marijuana; Neuronal Plasticity; Oxidopamine; Parkinson Disease; Plant Extracts; Rats; Rats, Wistar; Receptors, Dopamine D1 | 2021 |
THC-induced behavioral stereotypy in zebrafish as a model of psychosis-like behavior.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dronabinol; N-Methylaspartate; Piperidines; Psychotic Disorders; Psychotropic Drugs; Pyrazoles; Receptor, Cannabinoid, CB1; Stereotyped Behavior; Zebrafish | 2021 |
Chronic ∆-9-tetrahydrocannabinol administration delays acquisition of schedule-induced drinking in rats and retains long-lasting effects.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2022 |
Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability.
Topics: Animals; Aqueous Humor; Biological Availability; Cannabinoid Receptor Agonists; Cornea; Disease Models, Animal; Dronabinol; Drug Evaluation, Preclinical; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Prodrugs; Rabbits; Vitreous Body | 2017 |
BDNF overexpression prevents cognitive deficit elicited by adolescent cannabis exposure and host susceptibility interaction.
Topics: Adolescent; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cannabis; Cognition; Cognition Disorders; Disease Models, Animal; Dronabinol; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Psychotic Disorders | 2017 |
Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Benzodioxoles; Brain; Cannabinoid Receptor Agonists; Cyclohexanols; Disease Models, Animal; Dronabinol; Endocannabinoids; Excitatory Postsynaptic Potentials; Glycerides; Heterocyclic Compounds, 1-Ring; Locomotion; Male; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Pyridines; Signal Transduction | 2017 |
Single and combined effects of Δ
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cannabidiol; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Vincristine | 2017 |
Cannabinoid-Induced Tetrad in Mice.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Catalepsy; Disease Models, Animal; Dronabinol; Exploratory Behavior; Hypothermia; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Piperidines; Pyrazoles; Rimonabant | 2017 |
Delta-9-tetrahydrocannabinol decreases masticatory muscle sensitization in female rats through peripheral cannabinoid receptor activation.
Topics: Animals; Cannabinoid Receptor Agonists; Disease Models, Animal; Dronabinol; Female; Masseter Muscle; Mechanoreceptors; Myofascial Pain Syndromes; Nerve Growth Factor; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Trigeminal Ganglion | 2017 |
Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Corticosterone; Curcumin; Depressive Disorder, Major; Disease Models, Animal; Dopamine; Dronabinol; Drug Carriers; Lipids; MAP Kinase Kinase 1; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nanoparticles; PC12 Cells; Rats; Receptor, Cannabinoid, CB1 | 2017 |
Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.
Topics: Animals; Cannabis; Cell Line, Tumor; Disease Models, Animal; Dronabinol; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Nitro Compounds; PPAR gamma; Propionates | 2017 |
Cannabis constituent synergy in a mouse neuropathic pain model.
Topics: Analgesics; Animals; Cannabidiol; Cannabis; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia | 2017 |
Effects of Cannabinoid Agonists and Antagonists on Sleep and Breathing in Sprague-Dawley Rats.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Electroencephalography; Electromyography; Indoles; Male; Piperidines; Polysomnography; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Respiration; Sleep; Sleep Apnea, Central; Sleep, REM; Vagus Nerve | 2017 |
Comparison of cannabinoids with known analgesics using a novel high throughput zebrafish larval model of nociception.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Ibuprofen; Larva; Locomotion; Nociception; Pain; Principal Component Analysis; Time Factors; Tramadol; Zebrafish | 2018 |
Sex differences in antinociceptive response to Δ-9-tetrahydrocannabinol and CP 55,940 in the mouse formalin test.
Topics: Analgesics; Analysis of Variance; Animals; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Female; Formaldehyde; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Pain; Pain Measurement; Receptor, Cannabinoid, CB1; Sex Characteristics; Time Factors; Treatment Outcome | 2018 |
Effects of Δ9-THC and cannabidiol vapor inhalation in male and female rats.
Topics: Administration, Inhalation; Animals; Body Temperature; Cannabidiol; Disease Models, Animal; Dronabinol; Electronic Nicotine Delivery Systems; Female; Hypothermia; Locomotion; Male; Nociception; Rats; Rats, Wistar | 2018 |
Effect of cannabidiolic acid and ∆
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Cannabinoids; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Edema; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2018 |
THC and gabapentin interactions in a mouse neuropathic pain model.
Topics: Analgesics; Animals; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Gabapentin; Hyperalgesia; Male; Mice, Inbred C57BL; Motor Activity; Neuralgia; Sciatic Nerve; Time Factors; Touch | 2019 |
Neuronal nicotinic acetylcholine receptors mediate ∆
Topics: Animals; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Humans; Marijuana Abuse; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Nicotinic; Rimonabant; Substance Withdrawal Syndrome | 2020 |
Cannabinoids Reduce Inflammation but Inhibit Lymphocyte Recovery in Murine Models of Bone Marrow Transplantation.
Topics: Animals; Bone Marrow Transplantation; Cannabidiol; Disease Models, Animal; Dronabinol; Female; Graft vs Host Disease; Inflammation; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Treatment Outcome | 2019 |
Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse.
Topics: Age Factors; Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ganglionic Stimulants; Male; Microdialysis; Morphine; Nicotine; Nucleus Accumbens; Psychotropic Drugs; Rats; Substance-Related Disorders; Synaptic Transmission | 2020 |
Tolerance and dependence to Δ9-tetrahydrocannabinol in rhesus monkeys: Activity assessments.
Topics: Administration, Intravenous; Animals; Disease Models, Animal; Dronabinol; Drug Tolerance; Female; Hallucinogens; Humans; Macaca mulatta; Male; Motor Activity; Rimonabant; Substance Withdrawal Syndrome | 2019 |
Different pharmaceutical preparations of Δ
Topics: Animals; Behavior, Animal; Brain; Cannabinoid Receptor Agonists; Disease Models, Animal; Dosage Forms; Dronabinol; Lipids; Locomotion; Pharmaceutical Solutions; Prepulse Inhibition; Rats; Reflex, Startle; Schizophrenia; Solubility; Solvents | 2020 |
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats.
Topics: Animals; Behavior Observation Techniques; Cerebrovascular Circulation; Circle of Willis; Disease Models, Animal; Dronabinol; Female; Hippocampus; Humans; Magnetic Resonance Angiography; Male; Methylazoxymethanol Acetate; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia; Sensorimotor Cortex | 2019 |
Cannabinoids induce latent sensitization in a preclinical model of medication overuse headache.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Female; Headache Disorders, Secondary; Morpholines; Naphthalenes; Pain Measurement; Rats; Rats, Sprague-Dawley | 2020 |
Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome.
Topics: Animals; Cannabidiol; Cannabinoids; Cannabis; Cytokines; Disease Models, Animal; Dronabinol; Dysbiosis; Encephalomyelitis, Autoimmune, Experimental; Female; Gastrointestinal Microbiome; Inflammation; Interferon-gamma; Interleukin-17; Mice; Mice, Inbred C57BL; Multiple Sclerosis; RNA, Ribosomal, 16S | 2019 |
Natural cannabinoids improve dopamine neurotransmission and tau and amyloid pathology in a mouse model of tauopathy.
Topics: Amyloidosis; Animals; Behavior, Animal; Biogenic Monoamines; Cannabidiol; Disease Models, Animal; Dopamine; Dronabinol; Drug Combinations; Frontotemporal Dementia; Glutathione; Humans; Male; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Phytotherapy; Plant Extracts; Synaptic Transmission; Tauopathies | 2013 |
Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Disease Models, Animal; Dronabinol; Interferon-gamma; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Primary Cell Culture; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2013 |
Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus.
Topics: Animals; Antiemetics; Behavior, Animal; Body Temperature Regulation; Brain; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Lithium Chloride; Male; Motor Activity; Nausea; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Shrews; Time Factors; Vomiting | 2013 |
Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ(9) -tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Partial Agonism; Lithium Chloride; Male; Nausea; Phytochemicals; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant | 2013 |
Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat.
Topics: Analgesics, Non-Narcotic; Animals; Apnea; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Electromyography; Male; Muscle, Skeletal; Nodose Ganglion; Rats; Rats, Sprague-Dawley; Respiration; Serotonin | 2014 |
Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid.
Topics: Analgesics; Animals; Benzoxazines; Brain; Cannabinoid Receptor Agonists; Conditioning, Operant; Cues; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug-Seeking Behavior; Kynurenic Acid; Male; Memory, Short-Term; Morpholines; Naphthalenes; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reinforcement, Psychology; Saimiri; Secondary Prevention; Self Administration; Substance-Related Disorders; Sulfonamides; Thiazoles; Time Factors; Wakefulness | 2013 |
Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats.
Topics: Age Factors; Animals; Animals, Newborn; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Motor Activity; Phencyclidine; Prefrontal Cortex; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Stereotyped Behavior; Synaptic Transmission | 2014 |
Neuroprotective effects of the cannabinoid agonist HU210 on retinal degeneration.
Topics: Animals; Biomarkers; Cannabinoid Receptor Agonists; Cell Survival; Disease Models, Animal; Dronabinol; Electroretinography; Eye Proteins; Microscopy, Confocal; Neuroprotective Agents; Night Vision; Photic Stimulation; Presynaptic Terminals; Rats; Rats, Transgenic; Retina; Retinal Bipolar Cells; Retinitis Pigmentosa | 2014 |
Animals with a schizophrenia-like phenotype are differentially sensitive to the motivational effects of cannabinoid agonists in conditioned place preference.
Topics: Amphetamine; Animals; Avoidance Learning; Benzoxazines; Cannabinoid Receptor Agonists; Conditioning, Psychological; Disease Models, Animal; Dronabinol; Hippocampus; Male; Morpholines; Motivation; Motor Activity; Naphthalenes; Rats, Sprague-Dawley; Schizophrenia; Space Perception | 2014 |
Developmentally vitamin D-deficient rats show enhanced prepulse inhibition after acute Δ9-tetrahydrocannabinol.
Topics: Acoustic Stimulation; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Dronabinol; Exploratory Behavior; Locomotion; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Sensory Gating; Vitamin D Deficiency | 2014 |
Repeated but not acute treatment with ∆⁹-tetrahydrocannabinol disrupts prepulse inhibition of the acoustic startle: reversal by the dopamine D₂/₃ receptor antagonist haloperidol.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Antagonists; Dronabinol; Gait Disorders, Neurologic; Hallucinogens; Haloperidol; Male; Prepulse Inhibition; Psychoacoustics; Rats; Rats, Sprague-Dawley; Time Factors | 2014 |
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chemokine CCL2; Chromones; Disease Models, Animal; Dronabinol; Female; Hyperalgesia; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Paclitaxel; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha | 2015 |
Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation-induced cognitive damage.
Topics: Anilides; Animals; Arachidonic Acids; Brain; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cognition Disorders; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Encephalitis; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; PPAR gamma; Pyrazoles; Recognition, Psychology | 2014 |
Cannabinoids reward sensitivity in a neurodevelopmental animal model of schizophrenia: a brain stimulation reward study.
Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Benzoxazines; Brain; Brain Injuries; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dronabinol; Female; Hippocampus; Male; Morpholines; Motivation; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reward; Schizophrenia; Self Administration; Time Factors | 2014 |
St8sia2 deficiency plus juvenile cannabis exposure in mice synergistically affect higher cognition in adulthood.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Cell Adhesion Molecules, Neuronal; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Gene Expression Regulation; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Psychotropic Drugs; Sialyltransferases | 2014 |
AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner.
Topics: Animals; Body Temperature Regulation; CA1 Region, Hippocampal; CA2 Region, Hippocampal; CA3 Region, Hippocampal; Cannabinoid Receptor Agonists; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Enteric Nervous System; Gastrointestinal Motility; Hypothermia; Intestinal Mucosa; Intestines; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pain; Pain Threshold; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Stress, Psychological; Time Factors | 2015 |
Cannabinoids & Stress: impact of HU-210 on behavioral tests of anxiety in acutely stressed mice.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anxiety; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Male; Mice; Motor Activity; Random Allocation; Receptor, Cannabinoid, CB1; Stress, Psychological | 2015 |
Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist.
Topics: Animals; Body Temperature; Cannabinoid Receptor Antagonists; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Tolerance; Male; Mice; Morpholines; Motor Activity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance Withdrawal Syndrome | 2015 |
Δ9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption.
Topics: Analysis of Variance; Animals; Cannabidiol; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Fear; Male; Maze Learning; Memory; Memory Disorders; Rats; Rats, Wistar; Time Factors | 2015 |
A Sativex(®) -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis.
Topics: Animals; Cannabidiol; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Drug Therapy, Combination; Mice; Mice, Inbred Strains; Multiple Sclerosis; Plant Extracts; Theilovirus | 2015 |
Synergy between cannabidiol, cannabidiolic acid, and Δ⁹-tetrahydrocannabinol in the regulation of emesis in the Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Cannabidiol; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Female; Lithium Chloride; Male; Shrews; Vomiting | 2015 |
Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory.
Topics: Animals; Brain; Cannabinoid Receptor Agonists; Disease Models, Animal; Dronabinol; Emotions; Fear; Gene-Environment Interaction; Memory; Mice; Mice, Transgenic; Nerve Tissue Proteins; Proto-Oncogene Proteins c-fos; Receptor, Cannabinoid, CB1 | 2015 |
The impact of gonadal hormones on cannabinoid dependence.
Topics: Animals; Body Weight; Castration; Disease Models, Animal; Dronabinol; Drug Tolerance; Estrous Cycle; Female; Gonadal Hormones; Hormone Replacement Therapy; Male; Marijuana Abuse; Motor Activity; Pain Measurement; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sex Characteristics; Substance Withdrawal Syndrome; Time Factors | 2015 |
Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping.
Topics: Animals; Antiemetics; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Lithium Chloride; Male; Nausea; Rats; Rats, Sprague-Dawley; Saccharin | 2015 |
In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat.
Topics: Animals; Cannabinoid Receptor Agonists; Disease Models, Animal; Dronabinol; Gastrointestinal Motility; Gastrointestinal Tract; In Vitro Techniques; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2015 |
Effects of daily delta-9-tetrahydrocannabinol treatment on heroin self-administration in rhesus monkeys.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Conditioning, Operant; Disease Models, Animal; Dronabinol; Female; Heroin; Heroin Dependence; Macaca mulatta; Male; Narcotics; Reinforcement, Psychology; Self Administration | 2016 |
Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats.
Topics: Age Factors; Animals; Animals, Newborn; Cognition Disorders; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dronabinol; Encephalitis; Female; Gene Expression Regulation; Hallucinogens; Immobility Response, Tonic; Interpersonal Relations; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Swimming | 2015 |
THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia.
Topics: Animals; Arachidonic Acids; Benzamides; Carbamates; Disease Models, Animal; Dronabinol; Endocannabinoids; Hippocampus; Male; Phencyclidine; Polyunsaturated Alkamides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Up-Regulation | 2016 |
Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Bupropion; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Electric Stimulation; Formaldehyde; Hyperalgesia; Ketoprofen; Male; Medial Forebrain Bundle; Morphine; Neuralgia; Rats; Rats, Sprague-Dawley; Self Stimulation | 2016 |
Cannabinoid Receptor 2 Participates in Amyloid-β Processing in a Mouse Model of Alzheimer's Disease but Plays a Minor Role in the Therapeutic Properties of a Cannabis-Based Medicine.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cannabidiol; Cognition; Disease Models, Animal; Dronabinol; Humans; Male; Medical Marijuana; Memory; Mice, Inbred C57BL; Mice, Transgenic; Nootropic Agents; Presenilin-1; Random Allocation; Receptor, Cannabinoid, CB2; tau Proteins; Treatment Outcome | 2016 |
Alteration of transcriptional networks in the entorhinal cortex after maternal immune activation and adolescent cannabinoid exposure.
Topics: Age Factors; Animals; Cannabinoid Receptor Agonists; Disease Models, Animal; Dronabinol; Entorhinal Cortex; Female; Gene Expression; Gene Regulatory Networks; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Virus Diseases | 2016 |
Marijuana-derived Δ-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation.
Topics: Animals; Cytokines; Disease Models, Animal; Dronabinol; Female; Gene Expression Profiling; Gene Expression Regulation; Hypersensitivity, Delayed; Inflammation Mediators; Lymphocyte Activation; Mice; MicroRNAs; RNA Interference; Th1 Cells; Th17 Cells; Transcription Factors | 2016 |
Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung.
Topics: Actins; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Connective Tissue Growth Factor; Cytoprotection; Disease Models, Animal; Disease Progression; Dronabinol; Drug Administration Schedule; Hydroxyproline; Lung; Male; Mice, Inbred DBA; Phosphorylation; PPAR gamma; Pulmonary Fibrosis; Signal Transduction; Smad2 Protein; Smad3 Protein; Time Factors; Transforming Growth Factor beta1 | 2016 |
The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Cannabinoid Receptor Agonists; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dronabinol; Haloperidol; Hypothyroidism; Imidazoles; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Perchlorates; Phenotype; Potassium Compounds; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2017 |
Cannabis exacerbates depressive symptoms in rat model induced by reserpine.
Topics: Acetylcholinesterase; Animals; Cannabis; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Dronabinol; Hippocampus; Male; Motor Activity; Norepinephrine; Oxidative Stress; Rats, Wistar; Reserpine; Serotonin; Sodium-Potassium-Exchanging ATPase | 2017 |
The effects of cannabidiol and tetrahydrocannabinol on motion-induced emesis in Suncus murinus.
Topics: Animals; Antiemetics; Cannabidiol; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Motion Sickness; Receptor, Cannabinoid, CB1; Shrews; Vestibule, Labyrinth; Vomiting | 2008 |
Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Autoradiography; Cyclohexanols; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Exploratory Behavior; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Immunosuppressive Agents; Isotopes; Male; Olfactory Bulb; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Signal Transduction; Time Factors | 2009 |
The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortex.
Topics: Analysis of Variance; Animals; Animals, Newborn; Area Under Curve; Avoidance Learning; Cognition Disorders; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Dronabinol; Female; Glial Fibrillary Acidic Protein; Intracellular Signaling Peptides and Proteins; Maze Learning; Membrane Proteins; Neuronal Plasticity; Prefrontal Cortex; Proteomics; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptophysin; Tubulin | 2009 |
Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Corpus Striatum; Disease Models, Animal; Dronabinol; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Genotype; Glutamic Acid; Male; Mice; Mice, Mutant Strains; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Receptor, Cannabinoid, CB1; Superoxide Dismutase; Superoxide Dismutase-1; Synaptic Transmission | 2010 |
Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis.
Topics: Animals; Antigens, CD; Corpus Striatum; Dendrites; Disease Models, Animal; Dronabinol; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Glycoproteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Movement Disorders; Myelin-Oligodendrocyte Glycoprotein; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Peptide Fragments; Physical Conditioning, Animal; Silver Staining; Statistics, Nonparametric; Synapses; Synaptic Potentials | 2009 |
Effect of synthetic cannabinoid HU210 on memory deficits and neuropathology in Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cannabinoid Receptor Modulators; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Dronabinol; Female; Humans; Male; Maze Learning; Memory; Memory Disorders; Mice; Mice, Transgenic; Neuroprotective Agents; Plaque, Amyloid; Treatment Failure | 2010 |
Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.
Topics: Animals; Cerebral Cortex; Competitive Bidding; Disease Models, Animal; Dronabinol; Drug Interactions; Epilepsy; Evoked Potentials; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Pentylenetetrazole; Phosphorus Isotopes; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant | 2010 |
Antinociceptive activity of Delta9-tetrahydrocannabinol non-ionic microemulsions.
Topics: Administration, Oral; Analgesics; Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Dronabinol; Drug Compounding; Drug Stability; Emulsions; Injections, Intraperitoneal; Male; Mice; Pain; Pain Measurement; Pain Threshold; Polyethylene Glycols; Reaction Time; Solubility; Stearic Acids; Surface-Active Agents; Technology, Pharmaceutical; Temperature; Time Factors | 2010 |
Activity-based anorexia in C57/BL6 mice: effects of the phytocannabinoid, Delta9-tetrahydrocannabinol (THC) and the anandamide analogue, OMDM-2.
Topics: Animals; Anorexia Nervosa; Arachidonic Acids; Benzyl Compounds; Disease Models, Animal; Dronabinol; Energy Intake; Energy Metabolism; Feeding Behavior; Male; Mice; Mice, Inbred C57BL; Motor Activity; Physical Conditioning, Animal; Psychotropic Drugs; Weight Loss | 2010 |
A follow-up study: acute behavioural effects of Delta(9)-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice.
Topics: Animals; Disease Models, Animal; Dronabinol; Exploratory Behavior; Female; Genotype; Heterozygote; Maze Learning; Memory; Mice; Mice, Mutant Strains; Motor Activity; Neuregulin-1; Reflex, Startle; Schizophrenia; Social Behavior | 2010 |
The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.
Topics: Animals; Cannabidiol; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Therapy, Combination; Gastrointestinal Motility; In Vitro Techniques; Inflammation; Male; Peroxidase; Rats; Rats, Wistar; Sulfasalazine; Trinitrobenzenesulfonic Acid | 2010 |
Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.
Topics: Animals; Behavior, Animal; Cannabinoids; Cohort Studies; Corpus Striatum; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Huntington Disease; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Random Allocation; Receptor, Cannabinoid, CB1; Treatment Outcome | 2010 |
The endocannabinoid system links gut microbiota to adipogenesis.
Topics: Adipogenesis; Adipose Tissue; Animals; Arachidonic Acids; Bacterial Translocation; Caco-2 Cells; Cannabinoid Receptor Modulators; Disease Models, Animal; Dronabinol; Endocannabinoids; Glycerides; Humans; Intestinal Mucosa; Intestines; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Obesity; Permeability; Piperidines; Polyunsaturated Alkamides; Prebiotics; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; RNA, Messenger | 2010 |
The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Drug Tolerance; Exploratory Behavior; Genotype; Heterozygote; Male; Mice; Mice, Mutant Strains; Motor Activity; Neuregulin-1; Proto-Oncogene Proteins c-fos; Psychotropic Drugs; Reflex, Startle; Schizophrenia | 2011 |
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats.
Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dronabinol; Dyskinesia, Drug-Induced; Levodopa; Male; Parkinsonian Disorders; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant | 2010 |
A low-Δ9 tetrahydrocannabinol cannabis extract induces hyperphagia in rats.
Topics: Animals; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Hyperphagia; Male; Rats | 2010 |
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodioxoles; Cannabinoid Receptor Modulators; Diazepam; Disease Models, Animal; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Obsessive-Compulsive Disorder; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2011 |
Clozapine and SCH 23390 prevent the spatial working memory disruption induced by Δ9-THC administration into the medial prefrontal cortex.
Topics: Animals; Benzazepines; Clozapine; Disease Models, Animal; Dopamine Antagonists; Dronabinol; Male; Maze Learning; Memory Disorders; Prefrontal Cortex; Psychotropic Drugs; Rats; Rats, Wistar | 2011 |
Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's disease.
Topics: Animals; Antioxidants; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dopamine; Dronabinol; Glutamic Acid; Lipopolysaccharides; Male; Mice; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Substantia Nigra; Tyrosine 3-Monooxygenase | 2011 |
CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Female; Histamine H1 Antagonists; Hypersensitivity; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Loratadine; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain; Piperidines; Pruritus; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2011 |
Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock.
Topics: Analgesics, Non-Narcotic; Animals; Blood Volume; Cardiac Output; Celecoxib; Chromatography, Liquid; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Therapy, Combination; Female; Injections, Intravenous; Nonlinear Dynamics; Oxygen; Pyrazoles; Shock, Hemorrhagic; Sulfonamides; Swine; Tandem Mass Spectrometry | 2011 |
The cannabinoid receptor agonist THC attenuates weight loss in a rodent model of activity-based anorexia.
Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Anorexia; Body Weight; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Eating; Female; Lipid Metabolism; Motor Activity; Rats; Rats, Sprague-Dawley; Thermogenesis; Time Factors; Weight Loss | 2011 |
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.
Topics: Animals; Cannabidiol; Cannabinoids; Caudate Nucleus; Cells, Cultured; Disease Models, Animal; Disease Progression; Dronabinol; Drug Combinations; Huntington Disease; Male; Neostriatum; Neuroprotective Agents; Phytotherapy; Plant Extracts; Putamen; Rats; Rats, Sprague-Dawley | 2011 |
THC-methadone and THC-naltrexone interactions on discrimination, antinociception, and locomotion in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Locomotion; Male; Methadone; Naltrexone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2011 |
Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats.
Topics: Adrenergic Uptake Inhibitors; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Body Weight; Brain; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Exploratory Behavior; Fever; Hydroxyindoleacetic Acid; Interpersonal Relations; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Protein Binding; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin | 2011 |
Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network.
Topics: Amygdala; Animals; Behavior, Addictive; Brain; Cluster Analysis; Disease Models, Animal; Dronabinol; Ethanol; Gene Expression; Gene Regulatory Networks; Male; Mice; Mice, Inbred C57BL; Morphine; Nicotine; Principal Component Analysis; Real-Time Polymerase Chain Reaction; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders; Temperance; Time; Transcriptional Activation | 2012 |
Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dronabinol; Excitatory Amino Acid Antagonists; Food Preferences; Gene Expression Regulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Point Mutation; Receptor, Cannabinoid, CB1; Receptors, GABA-B; Sucrose | 2011 |
Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease.
Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Brain; Disease Models, Animal; Dronabinol; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agents; gamma-Aminobutyric Acid; Glutamates; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Morpholines; Motor Activity; Naphthalenes; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Piperidines; Potassium; Pyrazoles; Receptor, Cannabinoid, CB1; Statistics, Nonparametric; Synaptosomes; Trinucleotide Repeats; Tritium; Vesicular Glutamate Transport Protein 1; Vesicular Inhibitory Amino Acid Transport Proteins | 2012 |
Synthetic cannabinoid ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis.
Topics: Adult; Aged; Animals; Cannabinoids; Collagen; Disease Models, Animal; Dronabinol; Female; Fibroblasts; Fibrosis; Humans; Male; Mice; Middle Aged; Scleroderma, Systemic | 2012 |
Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cannabinoid Receptor Antagonists; Depression; Disease Models, Animal; Dronabinol; Frontal Lobe; Hippocampus; Male; MAP Kinase Signaling System; Olfactory Bulb; Piperidines; Pyrazoles; Rats; Rimonabant | 2012 |
The yin and yang of cannabis-induced psychosis: the actions of Δ(9)-tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia.
Topics: Animals; Animals, Newborn; Cannabidiol; Disease Models, Animal; Dronabinol; Humans; Marijuana Abuse; Mice; Psychoses, Substance-Induced; Rats; Schizophrenia | 2012 |
Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington's disease: role of CB1 and CB2 receptors.
Topics: Animals; Cannabidiol; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Combinations; Drug Therapy, Combination; Huntington Disease; Inflammation; Male; Malonates; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2012 |
Treatment with tetrahydrocannabinol (THC) prevents infertility in male cystic fibrosis mice.
Topics: Animals; Birth Weight; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Cystic Fibrosis; Disease Models, Animal; Dronabinol; Female; Fertility; Fertility Agents, Male; Infertility, Male; Litter Size; Male; Mice; Mice, Inbred CFTR; Pregnancy; Receptors, Cannabinoid | 2011 |
Behavioral alterations in cystic fibrosis mice are prevented by cannabinoid treatment in infancy.
Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Brain; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Cystic Fibrosis; Disease Models, Animal; Dronabinol; Male; Mice; Mice, Inbred CFTR; Motor Activity; Receptors, Cannabinoid | 2011 |
Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.
Topics: 4-Aminopyridine; Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Carbamates; Corpus Striatum; Disease Models, Animal; Dronabinol; Endocannabinoids; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ganciclovir; Glutamic Acid; Lateral Ventricles; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Stem Cells; Neuroprotective Agents; Polyunsaturated Alkamides; Stem Cells; Stroke | 2012 |
Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats.
Topics: Animals; Behavior, Animal; Binge-Eating Disorder; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Inverse Agonism; Drug Tolerance; Endocannabinoids; Energy Intake; Feeding Behavior; Female; Margarine; Piperidines; Pyrazoles; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction; Weight Loss | 2013 |
Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability.
Topics: Animals; Anxiety; Behavior, Animal; Cannabidiol; Cannabinoid Receptor Antagonists; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Drug Inverse Agonism; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Saccharin; Taste; Taste Perception | 2013 |
Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms.
Topics: Amylases; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cannabinoids; Ceruletide; Disease Models, Animal; Dronabinol; Edema; Enzyme Activation; Immunohistochemistry; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Pancreas, Exocrine; Pancreatitis; Peroxidase; Phosphorylation; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Trypsinogen | 2013 |
Cannabinoid HU210 protects isolated rat stomach against impairment caused by serum of rats with experimental acute pancreatitis.
Topics: Acute Disease; Animals; Antiemetics; Cannabinoids; Cells, Cultured; Cytoprotection; Disease Models, Animal; Dronabinol; Lipopolysaccharides; Male; Organ Culture Techniques; Pancreatitis; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Serum; Stomach | 2012 |
Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Glutamic Acid; Glycerides; Hydrolysis; In Vitro Techniques; Membrane Potentials; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Synaptic Transmission | 2002 |
Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea.
Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Lithium; Male; Nausea; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant | 2003 |
Attenuation of the ovalbumin-induced allergic airway response by cannabinoid treatment in A/J mice.
Topics: Adjuvants, Immunologic; Animals; Bronchoalveolar Lavage Fluid; Cannabinoids; Cannabinol; Cytokines; Disease Models, Animal; Dronabinol; Immunoglobulin E; Injections, Intraperitoneal; Lung; Male; Mice; Mice, Inbred A; Ovalbumin; Respiratory Hypersensitivity; Respiratory Mucosa; RNA, Messenger; Th2 Cells | 2003 |
Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212.
Topics: Animals; Benzoxazines; Brain; Cardiovirus Infections; Cytokines; Disease Models, Animal; Dronabinol; Female; Hypersensitivity, Delayed; Lymphocyte Activation; Mice; Morpholines; Multiple Sclerosis; Myelin Proteolipid Protein; Naphthalenes; Peptide Fragments; RNA, Messenger; Theilovirus; Viral Load | 2003 |
Self-administration of delta9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys.
Topics: Animals; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Injections, Intravenous; Male; Marijuana Abuse; Reinforcement Schedule; Saimiri; Self Administration | 2003 |
Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210.
Topics: Animals; Blood Pressure; Body Temperature; Brain Infarction; Brain Ischemia; Disability Evaluation; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Heart Rate; Hypothermia, Induced; Motor Activity; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rewarming; Treatment Outcome | 2003 |
Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate.
Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Corpus Striatum; Disease Models, Animal; Dronabinol; Electron Transport Complex II; Enzyme Inhibitors; Huntington Disease; Male; Malonates; Multienzyme Complexes; Oxidoreductases; Piperidines; Psychotropic Drugs; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Succinate Dehydrogenase | 2003 |
Combination of dexanabinol and tempol in focal cerebral ischemia: is there a ceiling effect?
Topics: Animals; Behavior, Animal; Body Weight; Brain Ischemia; Cyclic N-Oxides; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neuroprotective Agents; Rats; Rats, Inbred SHR; Recovery of Function; Spin Labels; Treatment Outcome | 2003 |
Medicinal cannabis: is delta9-tetrahydrocannabinol necessary for all its effects?
Topics: Animals; Anticonvulsants; Brain; Cannabis; Chromatography, High Pressure Liquid; Disease Models, Animal; Dronabinol; Epilepsy; Membrane Potentials; Mice; Multiple Sclerosis; Phytotherapy; Plant Preparations; Rats | 2003 |
Effects of coadministration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Body Temperature; Brain; Brain Chemistry; Cannabidiol; Chromatography, High Pressure Liquid; Corticosterone; Disease Models, Animal; Dronabinol; Drug Interactions; Formaldehyde; Male; Morphine; Motor Activity; Narcotics; Pain; Pain Measurement; Psychotropic Drugs; Radioimmunoassay; Rats; Time Factors | 2004 |
Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Cannabinoids; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Embryo, Mammalian; Humans; L-Lactate Dehydrogenase; Mice; Mice, Transgenic; Motor Neurons; Piperidines; Psychomotor Performance; Pyrazoles; Rimonabant; Spinal Cord; Superoxide Dismutase; tert-Butylhydroperoxide; Time Factors | 2004 |
Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala.
Topics: Amygdala; Analgesics; Animals; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Genes, fos; Male; Mice; Mice, Inbred ICR; Restraint, Physical; Stress, Psychological | 2005 |
Application of a new collagen-based sealant for the treatment of pancreatic injury.
Topics: Amylases; Animals; Body Fluids; Disease Models, Animal; Dronabinol; Fibrosis; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraoperative Complications; Laparoscopy; Necrosis; Pancreas; Polymers; Splenectomy; Swine | 2004 |
Pain reduction and lack of psychotropic effects with ajulemic acid: comment on the article by Sumariwalla et al.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cannabidiol; Clinical Trials, Phase I as Topic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dronabinol; Humans; Pain; Psychotropic Drugs | 2004 |
Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.
Topics: Animals; Autoradiography; Convulsants; Disease Models, Animal; Dopamine; Dronabinol; Drug Administration Schedule; Drug Interactions; gamma-Aminobutyric Acid; In Situ Hybridization; In Vitro Techniques; Male; Nitro Compounds; Propionates; Psychotropic Drugs; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Striatonigral Degeneration; Succinate Dehydrogenase; Time Factors | 2004 |
Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism.
Topics: Analysis of Variance; Animals; Body Temperature; Brain Infarction; Cannabidiol; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Fever; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Tetrazolium Salts; Time Factors | 2004 |
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Chemotaxis, Leukocyte; Disease Models, Animal; Disease Progression; Dronabinol; Humans; Inflammation; Interferon-gamma; Macrophages; Mice; Mice, Knockout; Receptor, Cannabinoid, CB2; Receptors, CCR2; Receptors, Chemokine; RNA, Messenger; Survival Rate; Th1 Cells; Thioglycolates; Tumor Necrosis Factor-alpha | 2005 |
Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dronabinol; Excitatory Amino Acid Antagonists; Inflammation; Ligation; Male; Motor Activity; Neuralgia; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2005 |
Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Catalepsy; Cell Line; Chromatography; Cricetinae; Cricetulus; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypothermia; Inflammation; Ligation; Male; Morpholines; Motor Activity; Naphthalenes; Pain; Pain Measurement; Pain Threshold; Radioligand Assay; Rats; Rats, Wistar; Rotarod Performance Test; Sciatic Neuropathy; Sulfur Isotopes; Time Factors; Tritium | 2005 |
Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Dronabinol; Male; Mice; Mice, Transgenic; Probability; Psychotropic Drugs; Superoxide Dismutase; Survival | 2005 |
Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting.
Topics: Analysis of Variance; Animals; Antiemetics; Association Learning; Cannabidiol; Cannabinoids; Conditioning, Classical; Disease Models, Animal; Dronabinol; Female; Lithium Chloride; Male; Nausea; Ondansetron; Serotonin Antagonists; Shrews; Vomiting, Anticipatory | 2006 |
Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite.
Topics: Adrenalectomy; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Axons; Brain Diseases; Cannabinoids; Corpus Callosum; Corticosterone; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Enzyme Inhibitors; Immunohistochemistry; Male; Molsidomine; Morpholines; Peroxynitrous Acid; Pyrazoles; Rats; Rats, Wistar | 2006 |
Exposure to a lithium-paired context elicits gaping in rats: A model of anticipatory nausea.
Topics: Animals; Antiemetics; Conditioning, Operant; Disease Models, Animal; Dronabinol; Infusions, Intravenous; Lithium; Male; Nausea; Ondansetron; Rats; Rats, Sprague-Dawley; Taste | 2006 |
Long-term voluntary consumption of MDMA and THC in rats is modified by individual and situational factors.
Topics: Animals; Behavior, Animal; Choice Behavior; Disease Models, Animal; Dronabinol; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Social Behavior; Substance-Related Disorders; Time Factors | 2006 |
Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Cartilage; Cells, Cultured; Disease Models, Animal; Dronabinol; Embryo, Mammalian; Fibroblasts; Humans; Interleukin-1alpha; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout; PPAR gamma; Rats; Synovial Fluid; Tumor Necrosis Factor-alpha | 2007 |
Mouse cerebellar nicotinic-cholinergic receptor modulation of Delta9-THC ataxia: role of the alpha4beta2 subtype.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cannabinoid Receptor Agonists; Cerebellar Ataxia; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Hexamethonium; Male; Marijuana Abuse; Mice; Microinjections; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Cannabinoid; Receptors, Nicotinic; Smoking; Time Factors | 2006 |
Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Brain; Brain Damage, Chronic; Cannabinoids; Cell Count; Disease Models, Animal; Dronabinol; Endocannabinoids; Gliosis; Glycerides; Microglia; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Plant Lectins; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Treatment Outcome | 2007 |
A novel role of cannabinoids: implication in the fever induced by bacterial lipopolysaccharide.
Topics: Animals; Benzoxazines; Binding, Competitive; Body Temperature; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Fever; Interleukin-6; Lipopolysaccharides; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant | 2007 |
Neuroprotective and intraocular pressure-lowering effects of (-)Delta9-tetrahydrocannabinol in a rat model of glaucoma.
Topics: Animals; Antihypertensive Agents; Cell Count; Cell Survival; Disease Models, Animal; Dronabinol; Glaucoma; Injections; Intraocular Pressure; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells | 2007 |
Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew.
Topics: Animals; Antiemetics; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Dronabinol; Gamma Rays; Locomotion; Morpholines; Naphthalenes; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Shrews; Vomiting | 2007 |
Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism.
Topics: Animals; Behavior, Animal; Cannabidiol; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Functional Laterality; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Mice; Motor Activity; Neuroprotective Agents; Perfusion; Peroxidase; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tetrazolium Salts; Time Factors | 2007 |
Effects of different substance misuse in genital reflexes of paradoxical sleep deprived male rats.
Topics: Analysis of Variance; Animals; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Disease Models, Animal; Dronabinol; Ejaculation; Ethanol; Genitalia, Male; Male; Penile Erection; Psychotropic Drugs; Rats; Rats, Wistar; Reflex; Sexual Behavior, Animal; Sleep Deprivation | 2007 |
Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.
Topics: Analysis of Variance; Animals; Association Learning; Cannabinoid Receptor Agonists; Cannabinoids; Cerebellar Diseases; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Exploratory Behavior; Mice; Mice, Inbred CBA; Mice, Neurologic Mutants; Motor Activity; Motor Skills; Muscle Strength; Nerve Degeneration; Random Allocation | 2007 |
Attenuation of allergic contact dermatitis through the endocannabinoid system.
Topics: Animals; Arachidonic Acids; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Chemokines; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Disease Models, Animal; Down-Regulation; Dronabinol; Endocannabinoids; Female; Glycerides; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Skin; Up-Regulation | 2007 |
Actions of N-arachidonyl-glycine in a rat neuropathic pain model.
Topics: Analgesics; Animals; Arachidonic Acids; Area Under Curve; Camphanes; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Glycine; Hyperalgesia; Male; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Sciatica | 2008 |
The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis.
Topics: Acute Disease; Adult; Animals; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Corpus Striatum; Disease Models, Animal; Dronabinol; Electrophysiology; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Female; Glycerides; Humans; Lymphocytes; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Neuroprotective Agents; Patch-Clamp Techniques; Polyunsaturated Alkamides; Synaptic Transmission; Tissue Culture Techniques | 2007 |
Evaluation of fatty acid amides in the carrageenan-induced paw edema model.
Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoids; Carrageenan; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Edema; Endocannabinoids; Ethanolamines; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oleic Acids; Polyunsaturated Alkamides | 2008 |
CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour.
Topics: Amygdala; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Brain; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Hippocampus; Male; Maze Learning; Microinjections; Motor Activity; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Time Factors | 2008 |
Local enhancement of cannabinoid CB1 receptor signalling in the dorsal hippocampus elicits an antidepressant-like effect.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Dentate Gyrus; Depression; Disease Models, Animal; Dronabinol; Hippocampus; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Stress, Psychological; Swimming | 2007 |
Delta9-tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors.
Topics: Animals; Arachidonic Acids; Body Temperature; Brain Ischemia; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Electroencephalography; Gerbillinae; Male; Memory; Motor Activity; Receptor, Cannabinoid, CB1; Receptors, Opioid; Time Factors; TRPV Cation Channels | 2007 |
Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Delta9-tetrahydrocannabinol.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dronabinol; Female; Flow Cytometry; Inflammation; Influenza A virus; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA; T-Lymphocytes | 2008 |
Therapeutic effects of Delta9-THC and modafinil in a marmoset Parkinson model.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benzhydryl Compounds; Callithrix; Disease Models, Animal; Dronabinol; Female; Male; Modafinil; Parkinsonian Disorders | 2008 |
Blockade of THC-seeking behavior and relapse in monkeys by the cannabinoid CB(1)-receptor antagonist rimonabant.
Topics: Analgesics, Opioid; Animals; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Cues; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Male; Marijuana Abuse; Morphine; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Saimiri; Secondary Prevention; Self Administration | 2008 |
Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells.
Topics: Alanine Transaminase; Animals; Apoptosis; Arachidonic Acids; Aspartate Aminotransferases; Cannabinoid Receptor Modulators; Cells, Cultured; Chemokines; Concanavalin A; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Female; Hepatitis, Autoimmune; Hepatocytes; In Situ Nick-End Labeling; Leukocytes; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polyunsaturated Alkamides; Receptors, Cannabinoid; T-Lymphocytes, Regulatory; Time Factors; Treatment Outcome | 2008 |
Approaches to assessing host resistance.
Topics: Animals; Disease Models, Animal; Dronabinol; Encephalomyocarditis virus; Enterovirus Infections; Environmental Pollutants; Escherichia coli Infections; Herpes Simplex; Immunity, Innate; Infections; Listeriosis; Malaria; Mice; Polychlorinated Biphenyls; Rats; Streptococcal Infections | 1982 |
Effect of dizocilpine (MK-801) on the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: Acetylcholine; Animals; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dronabinol; Haloperidol; Male; Mice; Oxotremorine; Parkinson Disease; Receptors, N-Methyl-D-Aspartate | 1994 |
A novel nonpsychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Ceftriaxone; Disease Models, Animal; Dronabinol; Drug Therapy, Combination; Male; Meningitis, Pneumococcal; Neuroprotective Agents; Rats; Tumor Necrosis Factor-alpha | 1996 |
Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia.
Topics: Animals; Arterial Occlusive Diseases; Disease Models, Animal; Dronabinol; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Hypertension; Ischemic Attack, Transient; Male; Neuroprotective Agents; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Tumor Necrosis Factor-alpha | 1999 |
Delta-9-tetrahydrocannabinol interferes with the establishment and the expression of conditioned rejection reactions produced by cyclophosphamide: a rat model of nausea.
Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Cyclophosphamide; Disease Models, Animal; Drinking; Dronabinol; Male; Nausea; Rats; Rats, Sprague-Dawley; Saccharin; Solutions; Taste | 1999 |
Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.
Topics: Animals; Arrhythmias, Cardiac; Cannabinoids; Disease Models, Animal; Dronabinol; Epinephrine; Ganglionic Blockers; Heart; Hexamethonium; Immunity, Innate; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Hyperalgesia; Morpholines; Naphthalenes; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sciatica | 2001 |
Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia.
Topics: Animals; Body Weight; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Encephalitis; Free Radicals; Infarction, Middle Cerebral Artery; Male; Movement Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Inbred SHR; Tetrazolium Salts | 2001 |
Antitumor effects of ajulemic acid (CT3), a synthetic non-psychoactive cannabinoid.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Cannabinoids; Cell Cycle; Diglycerides; Disease Models, Animal; Dronabinol; Drug Screening Assays, Antitumor; Glioma; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Psychotropic Drugs; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Tumor Cells, Cultured | 2001 |
Cannabinoid activity curtails cocaine craving.
Topics: Animals; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
A cannabinoid mechanism in relapse to cocaine seeking.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Recurrence; Rimonabant | 2001 |
The anti-inflammatory activities of cannabinoid receptor ligands in mouse peritonitis models.
Topics: Animals; Anti-Inflammatory Agents; Ascitic Fluid; Benzoxazines; Cell Movement; Chemokine CCL2; Chemokine CXCL2; Chemokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Enterotoxins; Female; Genotype; Ligands; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Monokines; Morpholines; Naphthalenes; Neutrophils; Peritonitis; Receptors, Cannabinoid; Receptors, Drug; Specific Pathogen-Free Organisms; Thioglycolates | 2001 |
Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat.
Topics: Acute Disease; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Carrageenan; Disease Models, Animal; Dronabinol; Edema; Endocannabinoids; Ethanolamines; Hindlimb; Hyperalgesia; Indomethacin; Inflammation; Male; Motor Activity; Palmitic Acids; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Delta-9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, exacerbates brain infection by Acanthamoeba.
Topics: Acanthamoeba; Amebiasis; Animals; Antibodies, Protozoan; Brain Diseases; Central Nervous System Protozoal Infections; Cyclophosphamide; Disease Models, Animal; Dronabinol; Female; Humans; Immunocompetence; Immunocompromised Host; Immunosuppressive Agents; Mice | 2001 |
Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats.
Topics: Animals; Cannabidiol; Cannabinoids; Cannabis; Disease Models, Animal; Dronabinol; Male; Nausea; Phytotherapy; Plant Preparations; Psychotropic Drugs; Rats; Rats, Sprague-Dawley | 2002 |
Muscular dystrophy in adult mice chronically treated with delta9-THC at behavioural doses.
Topics: Animals; Disease Models, Animal; Dronabinol; Muscles; Muscular Dystrophy, Animal | 1977 |
Anticonvulsant and neurotoxic effects of tetrahydrocannabinol stereoisomers.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Epilepsy; Male; Nervous System; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship | 1987 |
Dependence on tetrahydrocannabinol in rhesus monkeys.
Topics: Animals; Conditioning, Operant; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Drug Tolerance; Macaca; Macaca mulatta; Male; Naloxone; Solvents; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1986 |
Chronic marijuana usage and sleep-wakefulness cycles in cats.
Topics: Administration, Oral; Amygdala; Animals; Behavior, Animal; Cannabis; Cats; Cerebral Cortex; Circadian Rhythm; Disease Models, Animal; Dronabinol; Electrodes, Implanted; Electroencephalography; Humans; Male; Reticular Formation; Sleep; Sleep, REM; Substance-Related Disorders; Thalamus; Wakefulness | 1973 |
[An animal test model for evaluating drugs with anti-mass-psychotic activity].
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dronabinol; Ethanol; Female; Housing, Animal; Humans; Male; Mass Behavior; Models, Psychological; Psychotic Disorders; Psychotropic Drugs; Rodentia | 1974 |
Antiepileptic properties of 9 -tetrahydrocannabinol.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cannabis; Cats; Disease Models, Animal; Dronabinol; Electric Stimulation; Electroencephalography; Female; Frontal Lobe; Hippocampus; Hypothalamus; Male; Mammillary Bodies; Phytotherapy; Seizures; Thalamic Nuclei | 1973 |