Compounds > dronabinol
Page last updated: 2024-08-21

dronabinol and Astrocytoma, Grade IV

dronabinol has been researched along with Astrocytoma, Grade IV in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
de Paula, BHR; Doherty, GJ1
Brazil, L; Checketts, D; Jove, M; Miller, S; Sabel, M; Short, SC; Tayo, B; Twelves, C1
Barba, M; Dávila, D; García-Taboada, E; Guzmán, M; Hernández-Tiedra, S; López-Valero, I; Lorente, M; Rodríguez-Fornés, F; Saiz-Ladera, C; Salvador-Tormo, N; Sánchez-Gómez, P; Sepúlveda, JM; Torres, S; Velasco, G1
Andradas, C; Blasco-Benito, S; Caffarel, MM; Canela, EI; Fernández-Ruiz, J; Gómez-Cañas, M; Guzmán, M; Irving, AJ; Lluís, C; McCormick, PJ; Medrano, M; Moreno, E; Pazos, MR; Pérez-Gómez, E; Sánchez, C1
Alonso, A; Antón, Z; Goñi, FM; Hernández-Tiedra, S; Hervás, JH; Landajuela, A; Montes, LR; Velasco, G1
Allison, J; Christian, RT; Desprez, PY; Horowitz, MP; Lau, D; Lee, J; Limbad, C; Marcu, JP; McAllister, SD; Moore, DH; Pakdel, A; Yount, GL; Zielinski, AJ1
Barcia, J; García-Taboada, E; Guzmán, M; Hernández-Tiedra, S; Lorente, M; Rodríguez-Fornés, F; Salazar, M; Torres, S; Velasco, G1
Aberturas, Mdel R; García-Taboada, E; Gil-Alegre, ME; Hernán Pérez de la Ossa, D; Lorente, M; Molpeceres, J; Torres, S; Torres-Suárez, AI; Velasco, G1
Fischer, OM; Hart, S; Ullrich, A1
Abood, ME; Aldape, K; Chan, C; Luu, T; McAllister, SD; Moore, DH; Taft, RJ; Yount, G1
Blázquez, C; Carracedo, A; Egia, A; García, S; Gironella, M; Giroux, V; González-Feria, L; Guzmán, M; Iovanna, JL; Lorente, M; Malicet, C; Piris, MA; Velasco, G; Villuendas, R1
Blázquez, C; Duarte, MJ; Galve-Roperh, I; González-Feria, L; Guzmán, M; Ravina, J; Rosa, MC; Sánchez, C; Velasco, G1
Amariglio, N; Fisher, T; Galanti, G; Gallily, R; Kventsel, I; Lavie, G; Mechoulam, R; Rechavi, G; Shoham, J; Toren, A1
Blázquez, C; Carracedo, A; Egia, A; González-Feria, L; Guzmán, M; Haro, A; Lorente, M; Salazar, M; Velasco, G1

Trials

2 trial(s) available for dronabinol and Astrocytoma, Grade IV

ArticleYear
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Combinations; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Oral Sprays; Precision Medicine; Survival Analysis; Temozolomide; Treatment Outcome

2021
A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
    British journal of cancer, 2006, Jul-17, Volume: 95, Issue:2

    Topics: Adult; Aged; Biopsy; Brain Neoplasms; Cannabinoid Receptor Antagonists; Cell Proliferation; Disease Progression; Dronabinol; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Receptors, Cannabinoid; Safety; Survival Rate; Treatment Outcome; Tumor Cells, Cultured

2006

Other Studies

12 other study(ies) available for dronabinol and Astrocytoma, Grade IV

ArticleYear
Cannabinoids in glioblastoma multiforme-hype or hope?
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Proliferation; Cell Survival; Clinical Trials, Phase I as Topic; Dronabinol; Drug Combinations; Glioblastoma; Humans; Oral Sprays; Temozolomide; Treatment Outcome

2021
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Line, Tumor; Dronabinol; Female; Glioblastoma; Humans; Male; Mice, Nude; Neoplastic Stem Cells; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.
    The Journal of biological chemistry, 2014, Aug-08, Volume: 289, Issue:32

    Topics: Animals; Breast Neoplasms; Cannabinoids; Cell Line, Tumor; Dronabinol; Female; Gene Targeting; Glioblastoma; HEK293 Cells; Humans; Male; Mice; Mice, Nude; Neoplasms; Protein Structure, Quaternary; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Recombinant Proteins; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

2014
Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP.
    Autophagy, 2016, Volume: 12, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 8 Family; Cardiolipins; Cell Line, Tumor; Cell Membrane; Dronabinol; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Membranes; Mitophagy; Pressure; Protein Binding; Rotenone; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid

2016
Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:1

    Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cannabidiol; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dronabinol; Drug Screening Assays, Antitumor; Drug Synergism; Glioblastoma; Humans; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Proteins; Reactive Oxygen Species; Receptor, Cannabinoid, CB2

2010
A combined preclinical therapy of cannabinoids and temozolomide against glioma.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Dacarbazine; Dronabinol; Drug Resistance, Neoplasm; Drug Synergism; Glioblastoma; Humans; Mice; Mice, Nude; Random Allocation; Temozolomide; Transfection; Xenograft Model Antitumor Assays

2011
Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cannabidiol; Cannabis; Cell Proliferation; Dronabinol; Drug Delivery Systems; Glioblastoma; Humans; Mice; Polymers; Transplantation, Heterologous

2013
Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
    Cancer research, 2004, Mar-15, Volume: 64, Issue:6

    Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Apoptosis; Benzoxazines; Cannabinoids; Cell Division; Dronabinol; EGF Family of Proteins; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Glioblastoma; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Metalloendopeptidases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Phosphorylation; Proto-Oncogene Proteins; RNA Interference; Signal Transduction; Transcriptional Activation; Tumor Cells, Cultured

2004
Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells.
    Journal of neuro-oncology, 2005, Volume: 74, Issue:1

    Topics: Benzoxazines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Dronabinol; Glioblastoma; Humans; Morpholines; Naphthalenes; Neuroglia; Receptors, Cannabinoid; Tumor Cells, Cultured

2005
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells.
    Cancer cell, 2006, Volume: 9, Issue:4

    Topics: Activating Transcription Factor 4; Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biopsy; Cannabinoids; Cell Cycle Proteins; Dronabinol; Endoplasmic Reticulum; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Neoplasm Proteins; Neoplasms; Protein Serine-Threonine Kinases; Repressor Proteins; Signal Transduction; Transcription Factor CHOP; Tumor Cells, Cultured; Up-Regulation; Xenograft Model Antitumor Assays

2006
Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:6

    Topics: Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Division; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Down-Regulation; Dronabinol; E2F1 Transcription Factor; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thymidylate Synthase; Time Factors; Up-Regulation

2008
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
    Cancer research, 2008, Mar-15, Volume: 68, Issue:6

    Topics: Animals; Cannabinoids; Cell Line, Tumor; Ceramides; Down-Regulation; Dronabinol; Fumonisins; Glioblastoma; Glioma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Invasiveness; Rats; Receptor, Cannabinoid, CB2

2008