Page last updated: 2024-08-21

dronabinol and Alzheimer Disease

dronabinol has been researched along with Alzheimer Disease in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's6 (26.09)29.6817
2010's6 (26.09)24.3611
2020's8 (34.78)2.80

Authors

AuthorsStudies
Brown, B; Cai, J; Cao, C; Gordon, M; Hong, Y; Li, M; Lin, X; Morgan, D; Shen, N; Wang, Y; Yan, J; Zhang, X; Zhou, Q1
Brown, B; Cao, C; Chang, P; Fihurka, O; Gordon, MN; Hong, Y; Lin, X; Morgan, D; Shen, N; Wang, Y; Yan, J; Zhao, H; Zhou, Q1
Bentulila, Z; Break, EP; David, D; Doron, R; Ellenbogen, L; Franko, M; Nitzan, K; Sarne, Y; Shamir, A; Zoharetz, M1
Choi, P; Ham, J; Kim, J; Kim, JC; Kim, T; Park, YT1
Hřib, R; Landa, L; Slíva, J; Šulcová, A; Trojan, V1
Andreazza, AC; Black, SE; Gallagher, D; Herrmann, N; Kiss, A; Lanctôt, KL; Ruthirakuhan, M; Verhoeff, NPLG2
Baldasso, GM; Bicca, MA; Capasso, R; Dutra, RC; Gonçalves, ECD; Paes, RS1
Cooray, R; Gupta, V; Suphioglu, C1
Calabrese, EJ; Rubio-Casillas, A1
Black, SE; Gallagher, D; Herrmann, N; Kiss, A; Lanctôt, KL; Ruthirakuhan, M; Verhoeff, NPLG1
Amjad, H; Burhanullah, MH; Forester, BP; Monette, PJ; Outen, JD; Rosenberg, PB; Vandrey, R1
Cimander, KF; Emrich, HM; Müller-Vahl, KR; Schlimme, J; Schneider, U; Seifert, J1
Andrés-Benito, P; Aso, E; Carmona, M; Ferrer, I; Maldonado, R1
Cairns, R; Howard, R; Krishnan, S1
Bromley-Brits, K; Cai, F; Chen, B; He, G; Song, W; Zhang, X1
Blázquez, C; de Ceballos, ML; Gómez del Pulgar, T; Guzmán, M; Ramírez, BG1
Eichmann, U; Kunz, D; Mahlberg, R; Walther, S1
Campbell, VA; Gowran, A1
Passmore, MJ1
McLaughlin, J; Morris, J; Stelly, M; Volicer, BJ; Volicer, L1
Volicer, L1

Reviews

9 review(s) available for dronabinol and Alzheimer Disease

ArticleYear
The Main Therapeutic Applications of Cannabidiol (CBD) and Its Potential Effects on Aging with Respect to Alzheimer's Disease.
    Biomolecules, 2023, 09-26, Volume: 13, Issue:10

    Topics: Alzheimer Disease; Cannabidiol; Cannabinoids; Dronabinol; Humans

2023
Agitation, Oxidative Stress, and Cytokines in Alzheimer Disease: Biomarker Analyses From a Clinical Trial With Nabilone for Agitation.
    Journal of geriatric psychiatry and neurology, 2020, Volume: 33, Issue:4

    Topics: Aged; Alzheimer Disease; Biomarkers; Cognition; Cytokines; Dronabinol; Female; Humans; Male; Oxidative Stress; Psychomotor Agitation

2020
Terpenoids, Cannabimimetic Ligands, beyond the
    Molecules (Basel, Switzerland), 2020, Mar-29, Volume: 25, Issue:7

    Topics: Alzheimer Disease; Anxiety; Bicyclic Monoterpenes; Cannabidiol; Cannabinoid Receptor Agonists; Cannabis; Cognitive Dysfunction; Dronabinol; Humans; Inflammatory Bowel Diseases; Neuralgia; Neuroprotective Agents; Nootropic Agents; Schizophrenia; Sesquiterpenes; Terpenes

2020
Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson's and Alzheimer's Diseases: a Review.
    Molecular neurobiology, 2020, Volume: 57, Issue:11

    Topics: Alzheimer Disease; Animals; Cannabidiol; Dronabinol; Endocannabinoids; Humans; Inflammation; Parkinson Disease

2020
Biphasic effects of THC in memory and cognition.
    European journal of clinical investigation, 2018, Volume: 48, Issue:5

    Topics: Age Factors; Alzheimer Disease; Animals; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Hippocampus; Humans; Marijuana Smoking; Memory Disorders; Memory, Short-Term; Neurogenesis; Nootropic Agents; Receptor, Cannabinoid, CB1

2018
[Dronabinol in neuropsychiatric diseases].
    Schmerz (Berlin, Germany), 2004, Volume: 18 Suppl 2

    Topics: Alzheimer Disease; Analgesics, Non-Narcotic; Dronabinol; Humans; Nervous System Diseases; Neurologic Examination; Neuromuscular Diseases; Phytotherapy; Plant Extracts; Treatment Outcome

2004
Cannabinoids for the treatment of dementia.
    The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2

    Topics: Alzheimer Disease; Cannabinoids; Dementia; Dronabinol; Humans; Psychotropic Drugs

2009
Alzheimer's disease; taking the edge off with cannabinoids?
    British journal of pharmacology, 2007, Volume: 152, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cannabinoids; Cholinesterase Inhibitors; Dronabinol; Humans; Models, Biological; Phosphorylation; tau Proteins

2007
Tube feeding in Alzheimer's disease is avoidable.
    The journal of nutrition, health & aging, 1998, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Antidepressive Agents; Contraindications; Depression; Dronabinol; Eating; Enteral Nutrition; Humans; Psychotropic Drugs; Sertraline; Weight Loss

1998

Trials

3 trial(s) available for dronabinol and Alzheimer Disease

ArticleYear
Randomized Placebo-Controlled Trial of Nabilone for Agitation in Alzheimer's Disease.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:11

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Antipsychotic Agents; Cognition; Double-Blind Method; Dronabinol; Female; Homes for the Aged; Humans; Male; Nursing Homes; Psychiatric Status Rating Scales; Treatment Outcome

2019
Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia.
    Psychopharmacology, 2006, Volume: 185, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Dronabinol; Electroencephalography; Female; Hallucinogens; Humans; Male; Motor Activity; Pilot Projects; Psychomotor Agitation; Sleep Wake Disorders

2006
Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
    International journal of geriatric psychiatry, 1997, Volume: 12, Issue:9

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Anorexia; Antidepressive Agents; Antipsychotic Agents; Appetite Stimulants; Behavioral Symptoms; Cross-Over Studies; Dronabinol; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Severity of Illness Index; Time Factors; Treatment Outcome; Weight Gain

1997

Other Studies

11 other study(ies) available for dronabinol and Alzheimer Disease

ArticleYear
Low-Dose Delta-9-Tetrahydrocannabinol as Beneficial Treatment for Aged APP/PS1 Mice.
    International journal of molecular sciences, 2022, Mar-02, Volume: 23, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Dronabinol; Glycogen Synthase Kinase 3 beta; Maze Learning; Mice; Mice, Transgenic; Presenilin-1

2022
The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC.
    International journal of molecular sciences, 2022, Apr-12, Volume: 23, Issue:8

    Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Dronabinol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1

2022
An Ultra-Low Dose of ∆9-Tetrahydrocannabinol Alleviates Alzheimer's Disease-Related Cognitive Impairments and Modulates TrkB Receptor Expression in a 5XFAD Mouse Model.
    International journal of molecular sciences, 2022, Aug-21, Volume: 23, Issue:16

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Dronabinol; Mice; Mice, Transgenic; Receptor, trkB

2022
The Cannabinoids, CBDA and THCA, Rescue Memory Deficits and Reduce Amyloid-Beta and Tau Pathology in an Alzheimer's Disease-like Mouse Model.
    International journal of molecular sciences, 2023, Apr-06, Volume: 24, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cannabidiol; Cannabinoids; Cannabis; Dronabinol; Memory Disorders; Mice; Neuroprotective Agents

2023
Tetrahydrocannabinol Has Potential for Treating Agitation in Alzheimer's Disease.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:11

    Topics: Aggression; Alzheimer Disease; Dronabinol; Humans; Psychomotor Agitation

2019
24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer's Disease: Analyses from a Clinical Trial with Nabilone.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 71, Issue:1

    Topics: Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Cross-Sectional Studies; Dronabinol; Female; Humans; Hydroxycholesterols; Longitudinal Studies; Male; Psychomotor Agitation; Treatment Outcome

2019
Cannabinoid Receptor 2 Participates in Amyloid-β Processing in a Mouse Model of Alzheimer's Disease but Plays a Minor Role in the Therapeutic Properties of a Cannabis-Based Medicine.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 51, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cannabidiol; Cognition; Disease Models, Animal; Dronabinol; Humans; Male; Medical Marijuana; Memory; Mice, Inbred C57BL; Mice, Transgenic; Nootropic Agents; Presenilin-1; Random Allocation; Receptor, Cannabinoid, CB2; tau Proteins; Treatment Outcome

2016
Effect of synthetic cannabinoid HU210 on memory deficits and neuropathology in Alzheimer's disease mouse model.
    Current Alzheimer research, 2010, Volume: 7, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cannabinoid Receptor Modulators; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Dronabinol; Female; Humans; Male; Maze Learning; Memory; Memory Disorders; Mice; Mice, Transgenic; Neuroprotective Agents; Plaque, Amyloid; Treatment Failure

2010
Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-23, Volume: 25, Issue:8

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzoxazines; Cannabinoids; Cells, Cultured; Coculture Techniques; Dronabinol; Female; Humans; Injections, Intraventricular; Male; Maze Learning; Microglia; Middle Aged; Morpholines; Motor Activity; Naphthalenes; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide; Peptide Fragments; Plaque, Amyloid; Protein Processing, Post-Translational; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Signal Transduction; Tumor Necrosis Factor-alpha

2005
The cannabinoid receptor agonist nabilone for the treatment of dementia-related agitation.
    International journal of geriatric psychiatry, 2008, Volume: 23, Issue:1

    Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Dronabinol; Humans; Male; Psychomotor Agitation; Treatment Outcome

2008
Dronabinol in Alzheimer's disease.
    The Harvard mental health letter, 1998, Volume: 15, Issue:6

    Topics: Alzheimer Disease; Anorexia; Appetite Stimulants; Dronabinol; Humans

1998