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dronabinol and Akinetic-Rigid Variant of Huntington Disease

dronabinol has been researched along with Akinetic-Rigid Variant of Huntington Disease in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's3 (20.00)29.6817
2010's9 (60.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
England, TJ; Murphy, AJ; O'Sullivan, SE; Stone, NL1
Appendino, G; Bellido, ML; Cantarero, I; Casano, S; Del Río, C; Ferreiro-Vera, C; Meyer, S; Morello, G; Muñoz, E; Nadal, X; Navarrete, C; Palomares, B; Sánchez-Carnerero, C1
Djamshidian, A; Heim, B; Lücke, T; Peball, M; Saft, C; Seppi, K; Thiels, C; von Hein, SM1
Alonso Arias, MA; Fernández Ruiz, J; Galve-Roperh, I; García Caldentey, J; García de Yébenes Prous, J; García de Yébenes, MJ; García Ribas, G; García-Bermejo, ML; Guzmán, M; López-Sendón Moreno, JL; Ortega-Gutierrez, S; Resel, E; Ruiz Romero, C; Sagredo, O; Tolón, RM; Trigo Cubillo, P; Valdeolivas, S1
Curtis, A; Ives, N; Mitchell, I; Patel, S; Rickards, H1
Dragunow, M; Glass, M; Goodfellow, CE; Graham, ES; Scotter, EL1
Dowie, MJ; Faull, RL; Glass, M; Hannan, AJ; Howard, ML; Nicholson, LF1
Aguado, T; Alberch, J; Benito, C; Blázquez, C; Börner, C; Carrasco, C; Chiarlone, A; de Yébenes, JG; Díaz-Hernández, M; Diez-Zaera, M; Fernández-Ruiz, J; Galve-Roperh, I; Ginés, S; Guzmán, M; Julien, B; Kraus, J; Lucas, JJ; Lutz, B; Marsicano, G; Monory, K; Palazuelos, J; Paoletti, P; Pazos, MR; Resel, E; Romero, J; Ruiz, C; Sagredo, O; Salazar, M; Sendtner, M1
Fernández-Ruiz, J; Pazos, MR; Pertwee, RG; Ramos, JA; Sagredo, O; Satta, V1
Armida, M; Beggiato, S; Chiodi, V; Domenici, MR; Ferrante, A; Ferraro, L; Martire, A; Popoli, P; Potenza, RL; Tanganelli, S; Uchigashima, M; Watanabe, M1
Fernández-Ruiz, J; Pertwee, RG; Sagredo, O; Satta, V; Valdeolivas, S1
Bizat, N; Boyer, F; Brouillet, E; Fernández-Ruiz, J; Hantraye, P; Lastres-Becker, I1
Curtis, A; Rickards, H1
Emrich, HM; Müller-Vahl, KR; Schneider, U1
Consroe, P; Kennedy, K; Schram, K1

Reviews

1 review(s) available for dronabinol and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
A systematic review of minor phytocannabinoids with promising neuroprotective potential.
    British journal of pharmacology, 2020, Volume: 177, Issue:19

    Topics: Cannabidiol; Dronabinol; Humans; Huntington Disease; Seizures

2020

Trials

4 trial(s) available for dronabinol and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington's disease.
    Journal of neurology, 2016, Volume: 263, Issue:7

    Topics: Adult; Amino Acids; Amyloid beta-Peptides; Biogenic Monoamines; Cannabidiol; Cross-Over Studies; Dronabinol; Drug Combinations; Endocannabinoids; Female; Fibroblasts; Follow-Up Studies; Gene Expression Regulation; Humans; Huntington Disease; Male; Mental Status Schedule; MicroRNAs; Middle Aged; Outcome Assessment, Health Care; Peptide Fragments; Pilot Projects; Plant Extracts; Plant Structures; Severity of Illness Index; tau Proteins

2016
A pilot study using nabilone for symptomatic treatment in Huntington's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Nov-15, Volume: 24, Issue:15

    Topics: Adult; Aged; Anti-Anxiety Agents; Behavioral Symptoms; Cognition Disorders; Cross-Over Studies; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Female; Humans; Huntington Disease; Male; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Pilot Projects

2009
Nabilone increases choreatic movements in Huntington's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:6

    Topics: Chorea; Dronabinol; Humans; Huntington Disease; Male; Middle Aged; Neurologic Examination; Neuropsychological Tests

1999
Assay of plasma cannabidiol by capillary gas chromatography/ion trap mass spectroscopy following high-dose repeated daily oral administration in humans.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cannabidiol; Dronabinol; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Huntington Disease; Male; Middle Aged

1991

Other Studies

10 other study(ies) available for dronabinol and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.
    British journal of pharmacology, 2017, Volume: 174, Issue:23

    Topics: Animals; Cannabis; Cell Line, Tumor; Disease Models, Animal; Dronabinol; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Nitro Compounds; PPAR gamma; Propionates

2017
Cannabinoids for Treatment of Dystonia in Huntington's Disease.
    Journal of Huntington's disease, 2018, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Cannabidiol; Cannabinoids; Dronabinol; Drug Combinations; Dystonia; Female; Humans; Huntington Disease; Male; Treatment Outcome

2018
Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.
    British journal of pharmacology, 2010, Volume: 160, Issue:3

    Topics: Animals; Butadienes; Cell Culture Techniques; Cell Death; Cell Line, Transformed; Cerebellum; Cyclic AMP; Dronabinol; GTP-Binding Protein alpha Subunits; Humans; Huntingtin Protein; Huntington Disease; Mice; Mitogen-Activated Protein Kinase 3; Nerve Tissue Proteins; Neuroprotective Agents; Nitriles; Nuclear Proteins; PC12 Cells; Pertussis Toxin; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Dopamine; Rimonabant

2010
Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.
    Neuroscience, 2010, Sep-29, Volume: 170, Issue:1

    Topics: Animals; Behavior, Animal; Cannabinoids; Cohort Studies; Corpus Striatum; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Huntington Disease; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Random Allocation; Receptor, Cannabinoid, CB1; Treatment Outcome

2010
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 1

    Topics: Analysis of Variance; Animals; Blotting, Western; Cell Survival; Corpus Striatum; Dronabinol; Growth Hormone-Releasing Hormone; Huntington Disease; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Motor Activity; Neurons; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; Rotarod Performance Test

2011
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.
    Journal of neuroscience research, 2011, Volume: 89, Issue:9

    Topics: Animals; Cannabidiol; Cannabinoids; Caudate Nucleus; Cells, Cultured; Disease Models, Animal; Disease Progression; Dronabinol; Drug Combinations; Huntington Disease; Male; Neostriatum; Neuroprotective Agents; Phytotherapy; Plant Extracts; Putamen; Rats; Rats, Sprague-Dawley

2011
Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Brain; Disease Models, Animal; Dronabinol; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agents; gamma-Aminobutyric Acid; Glutamates; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Morpholines; Motor Activity; Naphthalenes; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Piperidines; Potassium; Pyrazoles; Receptor, Cannabinoid, CB1; Statistics, Nonparametric; Synaptosomes; Trinucleotide Repeats; Tritium; Vesicular Glutamate Transport Protein 1; Vesicular Inhibitory Amino Acid Transport Proteins

2012
Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington's disease: role of CB1 and CB2 receptors.
    ACS chemical neuroscience, 2012, May-16, Volume: 3, Issue:5

    Topics: Animals; Cannabidiol; Cannabinoids; Disease Models, Animal; Dronabinol; Drug Combinations; Drug Therapy, Combination; Huntington Disease; Inflammation; Male; Malonates; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2

2012
Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate.
    Neuroreport, 2003, May-06, Volume: 14, Issue:6

    Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Corpus Striatum; Disease Models, Animal; Dronabinol; Electron Transport Complex II; Enzyme Inhibitors; Huntington Disease; Male; Malonates; Multienzyme Complexes; Oxidoreductases; Piperidines; Psychotropic Drugs; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Succinate Dehydrogenase

2003
Nabilone could treat chorea and irritability in Huntington's disease.
    The Journal of neuropsychiatry and clinical neurosciences, 2006,Fall, Volume: 18, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Dronabinol; Female; Humans; Huntington Disease

2006