Page last updated: 2024-08-21

dronabinol and Aging

dronabinol has been researched along with Aging in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19909 (16.36)18.7374
1990's10 (18.18)18.2507
2000's13 (23.64)29.6817
2010's16 (29.09)24.3611
2020's7 (12.73)2.80

Authors

AuthorsStudies
Hillard, CJ; Stollenwerk, TM1
Bilkei-Gorzo, A; Gellner, AK; Komorowska-Müller, JA; Ravichandran, KA; Stein, V; Zimmer, A1
Burgdorf, CE; Hill, MN; Huang, C; Jing, D; Lee, FS; Mackie, K; Milner, TA; Pickel, VM; Rajadhyaksha, AM; Yang, R1
Stringfield, SJ; Torregrossa, MM1
Ali, B; Johnson, MB; Kelley-Baker, T; Mechtler, L; Swedler, D1
Ambrosio, E; Capellán, R; Gómez-Rubio, L; Higuera-Matas, A; Orihuel, J; Roura-Martínez, D; Ucha, M; Valverde, C1
Kloft, L; Mason, NL; Ramaekers, JG; Theunissen, EL1
Albayram, O; Bab, I; Bilkei-Gorzo, A; Draffehn, A; Dvir-Ginzberg, M; Imbeault, S; Michel, K; Oppenheimer, H; Piyanova, A; Rácz, I; Schultze, JL; Ulas, T; Zimmer, A1
Doron, R; Rachmany, L; Sarne, Y; Sasson, E; Toledano, R1
Bradshaw, HB; Leishman, E; Mackie, K; Murphy, M1
Boehm, SL; Kasten, CR; Mackie, K; Zhang, Y1
Ahmed, AI; Burger, DM; Colbers, A; Feuth, TB; Kramers, C; Rikkert, MG; van den Elsen, GA; van der Marck, MA1
Bye, C; Keeley, RJ; McDonald, RJ; Trow, J1
Keeley, RJ; McDonald, RJ1
Cheng, K; Flax, SM; Rice, KC; Riley, AL; Wakeford, AG1
Filipeanu, CM; Ketchum, MJ; Weed, PF; Winsauer, PJ1
Flax, SM; Pomfrey, RL; Riley, AL; Wakeford, AG1
Catanese, A; Gabaglio, M; Grilli, M; Marchi, M; Parolaro, D; Pittaluga, A; Prini, P; Rubino, T; Zamberletti, E1
Burston, JJ; Howard, DR; Kendler, SH; Selley, DE; Sim-Selley, LJ; Wiley, JL1
Evans, RL; Wiley, JL1
Bartesaghi, R; Braida, D; Capurro, V; Guidali, C; Guidi, S; Parolaro, D; Pinter, M; Realini, N; Rubino, T; Sala, M; Viganò, D1
Izenwasser, S; Reed, SC; Wade, D; Werling, LL1
Daugé, V; Giros, B; Morel, LJ1
Acheson, SK; Greenleaf, AL; Kuhn, CM; Moore, NL; Swartzwelder, HS; Wilson, WA1
Dalton, VS; Zavitsanou, K1
Dow-Edwards, D; Izenwasser, S1
Arnold, JC; Chesworth, R; Huang, XF; Karl, T; Long, LE; McGregor, IS1
Abdelwahab, SH; Acheson, SK; D'Abo, A; Levin, ED; Rezvani, AH; Risher, ML; Swartzwelder, HS; Swartzwelder, NA; Wilson, WA1
Harvey-White, J; Kunos, G; Liu, J; Wang, L; Zimmer, A1
Mallet, PE; McGregor, IS; O'Shea, M; Singh, ME1
O'connell, MM; Tokarz, ME; Wiley, JL; Wright, MJ1
Cha, YM; Chaudhry, S; Kuhn, CM; Schramm-Sapyta, NL; Swartzwelder, HS; Wilson, WA1
Fernández-Ruiz, J; Gómez, M; Hernández, M1
Kang-Park, MH; Kuhn, CM; Moore, SD; Swartzwelder, HS; Wilson, WA1
Bittigau, P; Hansen, HH; Ikonomidou, C; Krutz, B; Lutz, B; Marsicano, G; Pragst, F; Sifringer, M; Stefovska, V1
Campolongo, P; Carratù, MR; Cassano, T; Cuomo, V; Dipasquale, P; Gaetani, S; Macheda, T; Trezza, V1
Law, FC; So, EM1
Chakravarty, I; Ghosh, JJ1
Bartke, A; Blum, K; Briggs, A; Dalterio, S; DeLallo, L; Sweeney, C1
Bogdon, DL; Gota, CH; Gunnell, JC; Hum, GJ; Rieth, TE; Wada, JK1
Navarro, M; Rodríguez de Fonseca, F; Rubio, P1
Elsohly, MA; Engelman, K; Mattes, RD; Shaw, LM1
Bowen, S; Friedman, H; Nakano, Y; Pross, S; Widen, R1
Eldridge, JC; Landfield, PW1
Friedman, H; Nakano, Y; Pross, S1
Friedman, H; McHugh, S; Nakano, Y; Pross, S; Widen, R1
Fride, E; Mechoulam, R1
Friedman, H; Pross, S; Snella, E1
Bonnin, A; Castro, JG; de Miguel, R; Fernandez-Ruiz, JJ; Ramos, JA1
Friedman, H; Newton, C; Plescia, O; Pross, S; Ramarathinam, L; Widen, R1
Lefkowitz, SS; Pruess, MM1
Bartke, A; Burstein, S; Dalterio, S1
Carr, LA; Walters, DE1
Abel, EL; Harris, LS; McMillan, DE1
Jakubovic, A; McGeer, PL1

Reviews

2 review(s) available for dronabinol and Aging

ArticleYear
The why behind the high: determinants of neurocognition during acute cannabis exposure.
    Nature reviews. Neuroscience, 2021, Volume: 22, Issue:7

    Topics: Aging; Attention; Biological Variation, Individual; Biotransformation; Brain; Cannabinoids; Cannabis; Cognition; Consciousness; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Female; Humans; Learning; Male; Marijuana Smoking; Nerve Net; Neurotransmitter Agents; Personality; Psychomotor Performance; Psychotropic Drugs; Sex Characteristics; Smoke

2021
Neurotoxicity and drugs of abuse: cannabinoid interaction with brain glucocorticoid receptors.
    NIDA research monograph, 1993, Volume: 136

    Topics: Aging; Animals; Brain; Cannabinoids; Dronabinol; Glucocorticoids; Humans; Receptors, Glucocorticoid; Stress, Physiological

1993

Trials

3 trial(s) available for dronabinol and Aging

ArticleYear
Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: a randomized controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Analgesics, Non-Narcotic; Attention; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Electrocardiography; Female; Humans; Male; Pain Measurement; Reaction Time; Retrospective Studies

2014
Double-blind, randomized, crossover trial of nabilone vs. placebo in cancer chemotherapy.
    Cancer treatment reviews, 1982, Volume: 9 Suppl B

    Topics: Adolescent; Adult; Aged; Aging; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Dronabinol; Female; Humans; Male; Middle Aged; Placebos; Sex Factors; Vomiting

1982
Cannabinoids and appetite stimulation.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:1

    Topics: Adult; Aging; Appetite; Diet; Double-Blind Method; Dronabinol; Eating; Energy Metabolism; Female; Food Preferences; Humans; Male; Middle Aged; Satiety Response; Stimulation, Chemical

1994

Other Studies

50 other study(ies) available for dronabinol and Aging

ArticleYear
Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation.
    Cells, 2021, 12-11, Volume: 10, Issue:12

    Topics: Aging; Amphetamine; Animals; Behavior, Animal; Conditioning, Classical; Dronabinol; Extinction, Psychological; Fear; Female; Locomotion; Male; Maze Learning; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats, Sprague-Dawley; Reflex, Startle; Swimming

2021
Chronic low-dose Δ
    Scientific reports, 2023, 01-25, Volume: 13, Issue:1

    Topics: Aging; Animals; Cognition; Dendritic Spines; Dronabinol; Mice; Mice, Transgenic

2023
Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
    Science advances, 2020, Volume: 6, Issue:7

    Topics: Aging; Amidohydrolases; Animals; Axons; Choice Behavior; Dronabinol; Endocannabinoids; Female; Genetic Variation; Male; Mice, Inbred C57BL; Nerve Net; Nucleus Accumbens; Polymorphism, Single Nucleotide; Receptor, Cannabinoid, CB1; Reward; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2020
Intravenous self-administration of delta-9-THC in adolescent rats produces long-lasting alterations in behavior and receptor protein expression.
    Psychopharmacology, 2021, Volume: 238, Issue:1

    Topics: Aging; Animals; Behavior, Addictive; Brain; Dronabinol; Female; Injections, Intravenous; Male; Marijuana Smoking; Memory, Short-Term; Rats; Receptors, Cell Surface; Self Administration; Sex Characteristics

2021
Cannabis and crash risk among older drivers.
    Accident; analysis and prevention, 2021, Volume: 152

    Topics: Accidents, Traffic; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Automobile Driving; Cannabis; Dronabinol; Female; Humans; Illicit Drugs; Male; Middle Aged; Risk; Virginia; Young Adult

2021
Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ
    Brain research, 2021, 08-01, Volume: 1764

    Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dronabinol; Drug Interactions; Female; Genes, fos; Hallucinogens; Hypothalamus, Posterior; Immunohistochemistry; Male; Motor Cortex; Rats; Rats, Wistar; Sex Characteristics

2021
A chronic low dose of Δ
    Nature medicine, 2017, Volume: 23, Issue:6

    Topics: Acetylation; Aging; Animals; Behavior, Animal; Cognition; Cognitive Aging; Cognitive Dysfunction; Dendritic Spines; Dronabinol; Endocannabinoids; Gene Expression Regulation, Developmental; Hippocampus; Histone Code; Memory, Long-Term; Mice; Mice, Knockout; Receptor, Cannabinoid, CB1; Spatial Learning; Spatial Memory; Transcriptome

2017
Reversal of age-related cognitive impairments in mice by an extremely low dose of tetrahydrocannabinol.
    Neurobiology of aging, 2018, Volume: 61

    Topics: Aging; Animals; Brain; Cognitive Dysfunction; Dronabinol; Female; Injections, Intraperitoneal; Magnetic Resonance Imaging; Mice; Psychotropic Drugs

2018
Δ
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018, Volume: 1863, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Cell Death; Cognition; Dronabinol; Female; Gene Expression Profiling; Hippocampus; Lipid Metabolism; Metabolome; Mice; Neurogenesis; Signal Transduction; Transcription, Genetic; Transcriptome

2018
Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC).
    Behavior genetics, 2018, Volume: 48, Issue:3

    Topics: Aging; Animals; Crosses, Genetic; Dronabinol; Female; Inheritance Patterns; Male; Mice; Motor Activity; Phenotype; Selection, Genetic; Time Factors

2018
Part II: Strain- and sex-specific effects of adolescent exposure to THC on adult brain and behaviour: Variants of learning, anxiety and volumetric estimates.
    Behavioural brain research, 2015, Jul-15, Volume: 288

    Topics: Aging; Animals; Anxiety; Brain; Dronabinol; Female; Learning; Male; Memory; Motor Skills; Organ Size; Psychological Tests; Psychotropic Drugs; Rats, Long-Evans; Rats, Wistar; Sex Characteristics; Species Specificity

2015
Part III: Principal component analysis: bridging the gap between strain, sex and drug effects.
    Behavioural brain research, 2015, Jul-15, Volume: 288

    Topics: Aging; Animals; Anxiety; Brain; Dronabinol; Female; Learning; Male; Memory; Motor Skills; Organ Size; Principal Component Analysis; Psychological Tests; Psychotropic Drugs; Rats, Long-Evans; Rats, Wistar; Sex Characteristics; Species Specificity

2015
Effect of norbinaltorphimine on ∆⁹-tetrahydrocannabinol (THC)-induced taste avoidance in adolescent and adult Sprague-Dawley rats.
    Psychopharmacology, 2015, Volume: 232, Issue:17

    Topics: Aging; Animals; Appetite Stimulants; Avoidance Learning; Dose-Response Relationship, Drug; Dronabinol; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Taste; Taste Perception

2015
Chronic Δ9-Tetrahydrocannabinol during Adolescence Differentially Modulates Striatal CB1 Receptor Expression and the Acute and Chronic Effects on Learning in Adult Rats.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 356, Issue:1

    Topics: Aging; Animals; Body Weight; Conditioning, Operant; Corpus Striatum; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Female; Hippocampus; Learning; Male; Psychomotor Performance; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Sex Characteristics

2016
Adolescent delta-9-tetrahydrocannabinol (THC) exposure fails to affect THC-induced place and taste conditioning in adult male rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 140

    Topics: Aging; Animals; Avoidance Learning; Conditioning, Operant; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Male; Rats; Rats, Sprague-Dawley; Taste

2016
Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats.
    Pharmacological research, 2016, Volume: 111

    Topics: Aging; Animals; Astrocytes; Behavior, Animal; Dronabinol; Glutamic Acid; Hippocampus; Interpersonal Relations; Male; Memory; Phenotype; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Swimming; Synapses

2016
Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats.
    Neuropharmacology, 2008, Volume: 55, Issue:7

    Topics: Aging; Animals; Antipsychotic Agents; Cells, Cultured; CHO Cells; Clozapine; Cricetinae; Cricetulus; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Dronabinol; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Male; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Rimonabant; Sex Characteristics; Signal Transduction

2008
To breed or not to breed? Empirical evaluation of drug effects in adolescent rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2009, Volume: 27, Issue:1

    Topics: Aging; Animals; Antipsychotic Agents; Breeding; Catalepsy; Clozapine; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Environment; Female; Haloperidol; Male; Motor Activity; Neuropharmacology; Pain Threshold; Psychotropic Drugs; Rats; Rats, Long-Evans; Sex Characteristics; Stress, Psychological

2009
Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood.
    Hippocampus, 2009, Volume: 19, Issue:8

    Topics: Aging; Animals; Avoidance Learning; Cognition Disorders; Dendrites; Disks Large Homolog 4 Protein; Dronabinol; Glial Fibrillary Acidic Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Maze Learning; Membrane Proteins; Memory; Neuronal Plasticity; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptophysin; Tubulin; Vesicle-Associated Membrane Protein 2

2009
Chronic nicotine alters cannabinoid-mediated locomotor activity and receptor density in periadolescent but not adult male rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2009, Volume: 27, Issue:3

    Topics: Adolescent; Aging; Analgesics; Animals; Cannabinoids; Cyclohexanols; Dronabinol; Female; Humans; Male; Motor Activity; Nicotine; Nicotinic Agonists; Piperidines; Psychotropic Drugs; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid

2009
Adolescent exposure to chronic delta-9-tetrahydrocannabinol blocks opiate dependence in maternally deprived rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:11

    Topics: Aging; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Brain; Conditioning, Classical; Dronabinol; Enkephalins; Male; Maternal Deprivation; Morphine; Opioid-Related Disorders; Protein Precursors; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; RNA, Messenger; Self Administration; Space Perception; Time Factors

2009
Role of cannabinoid receptor type 1 desensitization in greater tetrahydrocannabinol impairment of memory in adolescent rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:2

    Topics: Aging; Animals; Dronabinol; Drug Tolerance; Fluorescent Antibody Technique; Hippocampus; Male; Maze Learning; Memory; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Spatial Behavior

2010
Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brain.
    Journal of chemical neuroanatomy, 2010, Volume: 40, Issue:4

    Topics: Aging; Animals; Arabidopsis Proteins; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Transcription Factors

2010
Pretreatment with Δ9-tetrahydrocannabinol (THC) increases cocaine-stimulated activity in adolescent but not adult male rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Dyskinesia, Drug-Induced; Male; Marijuana Smoking; Motor Activity; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors

2012
Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:1

    Topics: Aging; Animals; Dronabinol; Exploratory Behavior; Male; Membrane Proteins; Mice; Mice, Transgenic; Motor Activity; Mutation; Neuregulin-1; Recurrence; Reflex, Startle; Social Behavior

2013
Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats.
    Neuroscience letters, 2012, Oct-03, Volume: 527, Issue:1

    Topics: Aging; Animals; Decision Making; Dronabinol; Drug Combinations; Ethanol; Form Perception; Male; Mental Recall; Rats; Rats, Sprague-Dawley; Recognition, Psychology

2012
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Feb-04, Volume: 100, Issue:3

    Topics: Aging; Alcohol Drinking; Animals; Blotting, Western; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanol; Fatty Acids, Unsaturated; Feeding Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred C57BL; Mice, Transgenic; Pertussis Toxin; Piperidines; Protein Binding; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction; Tissue Distribution

2003
Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:4

    Topics: Aging; Animals; Anxiety; Behavior, Animal; Cannabinoids; Cognition; Conditioning, Operant; Cyclohexanols; Dronabinol; Exploratory Behavior; Female; Hallucinogens; Interpersonal Relations; Learning; Memory Disorders; Memory, Short-Term; Motor Activity; Psychomotor Performance; Rats; Rats, Wistar

2004
Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Female; Male; Psychotropic Drugs; Rats; Rats, Long-Evans; Sex Factors

2007
Differential anxiogenic, aversive, and locomotor effects of THC in adolescent and adult rats.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adrenocorticotropic Hormone; Age Factors; Aging; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Corticosterone; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Male; Motor Activity; Psychotropic Drugs; Rats; Taste; Time Factors

2007
The activation of cannabinoid receptors during early postnatal development reduces the expression of cell adhesion molecule L1 in the rat brain.
    Brain research, 2007, May-11, Volume: 1145

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Cell Differentiation; Cell Movement; Cell Proliferation; Down-Regulation; Dronabinol; Female; Male; Nerve Fibers, Myelinated; Neural Cell Adhesion Molecule L1; Neurites; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; RNA, Messenger; Sex Characteristics; Sex Factors; Telencephalon

2007
Differential sensitivity of GABA A receptor-mediated IPSCs to cannabinoids in hippocampal slices from adolescent and adult rats.
    Journal of neurophysiology, 2007, Volume: 98, Issue:3

    Topics: Aging; Animals; Cannabinoids; Dronabinol; Evoked Potentials; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2007
Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity.
    Annals of neurology, 2008, Volume: 64, Issue:1

    Topics: Aging; Alcohol-Induced Disorders, Nervous System; Animals; Animals, Newborn; Benzoxazines; Brain; Cannabinoids; Cell Death; Central Nervous System Depressants; Dose-Response Relationship, Drug; Dronabinol; Drug Resistance; Drug Synergism; Ethanol; Excitatory Amino Acid Antagonists; GABA Agonists; Mice; Mice, Knockout; Morpholines; Naphthalenes; Nerve Degeneration; Neurotoxins; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1

2008
Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats.
    Psychopharmacology, 2008, Volume: 198, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Anxiety; Body Weight; Dronabinol; Emotions; Female; Hallucinogens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reproduction; Social Behavior; Social Isolation; Vocalization, Animal

2008
Induction studies of delta 1-tetrahydrocannabinol metabolism by rat and rabbit lungs.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1981, Volume: 69C, Issue:1

    Topics: Aging; Animals; Dronabinol; Enzyme Induction; Lung; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Rabbits; Rats; Subcellular Fractions

1981
Influence of cannabis and delta-9-tetrahydrocannabinol on the biochemistry of the male reproductive organs.
    Biochemical pharmacology, 1981, Feb-15, Volume: 30, Issue:4

    Topics: Aging; Animals; Cannabis; Citrates; Dronabinol; Epididymis; Fructose; Genitalia, Male; Male; Prostate; Rats; Seminal Vesicles; Testis

1981
Perinatal exposure to delta 9-THC in mice: altered enkephalin and norepinephrine sensitivity in vas deferens.
    Substance and alcohol actions/misuse, 1980, Volume: 1, Issue:5-6

    Topics: Aging; Animals; Dronabinol; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Mice; Muscle, Smooth; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Vas Deferens

1980
Sex-dimorphic psychomotor activation after perinatal exposure to (-)-delta 9-tetrahydrocannabinol. An ontogenic study in Wistar rats.
    Psychopharmacology, 1994, Volume: 116, Issue:4

    Topics: Aging; Animals; Behavior, Animal; Corticosterone; Dronabinol; Exploratory Behavior; Female; Grooming; Lactation; Light; Male; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sex Characteristics

1994
Effects of marijuana on spleen lymphocytes from mice of different age groups.
    Advances in experimental medicine and biology, 1993, Volume: 335

    Topics: Aging; Animals; CD3 Complex; Cell Division; Concanavalin A; Dronabinol; Female; Flow Cytometry; Interleukin-2; Lymphocytes; Mice; Mice, Inbred BALB C; Spleen

1993
Contrasting effect of delta-9-tetrahydrocannabinol on IL-2 activity in spleen and lymph node cells of mice of different ages.
    Life sciences, 1993, Volume: 52, Issue:1

    Topics: Aging; Animals; Dronabinol; Flow Cytometry; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Spleen

1993
Age related immunomodulation in murine splenocytes induced by delta-9-tetrahydrocannabinol (THC).
    Mechanisms of ageing and development, 1993, Volume: 68, Issue:1-3

    Topics: Adjuvants, Immunologic; Aging; Animals; Dronabinol; Female; Mice; Mice, Inbred BALB C; Spleen; T-Lymphocytes

1993
Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice.
    Brain research. Developmental brain research, 1996, Aug-20, Volume: 95, Issue:1

    Topics: Aging; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Cannabinoids; Dronabinol; Endocannabinoids; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pain Measurement; Polyunsaturated Alkamides

1996
Relationship of aging and cytokines to the immunomodulation by delta-9-tetrahydrocannabinol on murine lymphoid cells.
    International journal of immunopharmacology, 1995, Volume: 17, Issue:12

    Topics: Adjuvants, Immunologic; Aging; Animals; Cytokines; Dronabinol; Female; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Spleen; T-Lymphocytes; Thymus Gland

1995
Effects of perinatal exposure to delta 9-tetrahydrocannabinol on the fetal and early postnatal development of tyrosine hydroxylase-containing neurons in rat brain.
    Journal of molecular neuroscience : MN, 1996,Winter, Volume: 7, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Dronabinol; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Male; Neurons; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sex Characteristics; Tyrosine 3-Monooxygenase

1996
Differential immunologic modulatory effects of tetrahydrocannabinol as a function of age.
    Mechanisms of ageing and development, 1997, Volume: 96, Issue:1-3

    Topics: Adjuvants, Immunologic; Aging; Animals; CD4-CD8 Ratio; Cytokines; Dronabinol; Immune System; Mice; Mice, Inbred BALB C; Spleen

1997
Influence of maturity on immunosuppression by delta9-tetrahydrocannabinol.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:3

    Topics: Aging; Animals; Antibody Formation; Body Weight; Dronabinol; Immunity; Immunity, Cellular; Immunosuppression Therapy; Lymphocyte Activation; Male; Mice; Spleen

1978
Cannabinoids inhibit testosterone secretion by mouse testes in vitro.
    Science (New York, N.Y.), 1977, Jun-24, Volume: 196, Issue:4297

    Topics: Aging; Animals; Cannabinoids; Cannabinol; Dose-Response Relationship, Drug; Dronabinol; In Vitro Techniques; Male; Mice; Testis; Testosterone

1977
Perinatal exposure to cannabinoids alters neurochemical development in rat brain.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:1

    Topics: Aging; Animals; Brain; Brain Chemistry; Cannabinoids; Catecholamines; Corpus Striatum; Dronabinol; Female; Male; Prazosin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Tyrosine 3-Monooxygenase

1988
Tolerance to the hypothermic effects of 9-tetrahydrocannabinol as a function of age in the chicken.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Body Temperature; Cannabis; Chickens; Depression, Chemical; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Male; Tritium

1973
Inhibition of rat brain protein and nucleic acid synthesis by cannabinoids in vitro.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Cannabis; Carbon Dioxide; Carbon Isotopes; Cerebral Cortex; Depression, Chemical; Dronabinol; In Vitro Techniques; Kinetics; Leucine; Male; Nerve Tissue Proteins; Nucleic Acids; Oxygen Consumption; Potassium; Protoveratrines; Rats; Stimulation, Chemical; Uracil; Uracil Nucleotides; Uridine

1972