Page last updated: 2024-11-04

dpi 201-106 and Long QT Syndrome

dpi 201-106 has been researched along with Long QT Syndrome in 2 studies

DPI 201-106: structure given in first source

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
" DPI 201-106 is an experimental drug that produces QT prolongation by reducing Na(+) channel inactivation, thereby mimicking congenital long QT syndrome type 3 (LQT3)."7.74Functional interaction between DPI 201-106, a drug that mimics congenital long QT syndrome, and sevoflurane on the guinea-pig cardiac action potential. ( Chen, XL; Kang, J; Rampe, D; Reynolds, WP, 2007)
" DPI 201-106 is an experimental drug that produces QT prolongation by reducing Na(+) channel inactivation, thereby mimicking congenital long QT syndrome type 3 (LQT3)."3.74Functional interaction between DPI 201-106, a drug that mimics congenital long QT syndrome, and sevoflurane on the guinea-pig cardiac action potential. ( Chen, XL; Kang, J; Rampe, D; Reynolds, WP, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kühlkamp, V1
Mewis, C1
Bosch, R1
Seipel, L1
Kang, J1
Chen, XL1
Reynolds, WP1
Rampe, D1

Trials

1 trial available for dpi 201-106 and Long QT Syndrome

ArticleYear
Delayed sodium channel inactivation mimics long QT syndrome 3.
    Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:1

    Topics: Cardiotonic Agents; Electrocardiography; Electrophysiology; Female; Humans; Infusions, Intravenous;

2003

Other Studies

1 other study available for dpi 201-106 and Long QT Syndrome

ArticleYear
Functional interaction between DPI 201-106, a drug that mimics congenital long QT syndrome, and sevoflurane on the guinea-pig cardiac action potential.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:12

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Cardiotonic Agents; Guinea Pigs; Heart; Long QT

2007