dpi 201-106 has been researched along with Heart Failure in 6 studies
DPI 201-106: structure given in first source
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was designed to characterize the positive inotropic response to DPI 201-106 in isolated papillary muscle strips obtained from heart failure patients undergoing surgery." | 3.67 | Inotropic response to DPI 201-106 in the failing human heart. ( Böhm, M; Diet, F; Erdmann, E; Kemkes, B; Wankerl, M, 1989) |
| "In contrast, congestive heart failure and myocardial hypertrophy are associated with increased exchanger activity and a decreased inotropic state." | 2.40 | The sodium-calcium ion membrane exchanger: physiologic significance and pharmacologic implications. ( Fransua, M; Frishman, WH; Yashar, PR, 1998) |
| "BDF 9148 induced an increase in force of contraction that was accompanied by prolongation of action potential duration." | 1.29 | Comparison of the action potential prolonging and positive inotropic activity of DPI 201-106 and BDF 9148 in human ventricular myocardium. ( Amos, GJ; Hoey, A; Ravens, U, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoey, A | 1 |
| Amos, GJ | 1 |
| Ravens, U | 1 |
| Yashar, PR | 1 |
| Fransua, M | 1 |
| Frishman, WH | 1 |
| Böhm, M | 2 |
| Diet, F | 2 |
| Kemkes, B | 1 |
| Wankerl, M | 1 |
| Erdmann, E | 2 |
| Pieske, B | 1 |
| Kostis, JB | 1 |
| Lacy, CR | 1 |
| Raia, JJ | 1 |
| Dworkin, JH | 1 |
| Warner, RG | 1 |
| Casazza, LA | 1 |
| Hogan, JC | 1 |
| Greenbaum, RA | 1 |
| Lunnon, MW | 1 |
| Hilson, AJ | 1 |
| Evans, TR | 1 |
1 review available for dpi 201-106 and Heart Failure
| Article | Year |
|---|---|
The sodium-calcium ion membrane exchanger: physiologic significance and pharmacologic implications.
Topics: Azetidines; Calcium; Cardiotonic Agents; Heart Failure; Myocardial Ischemia; Piperazines; Protein Co | 1998 |
1 trial available for dpi 201-106 and Heart Failure
| Article | Year |
|---|---|
DPI 201-106 for severe congestive heart failure.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiograph | 1987 |
4 other studies available for dpi 201-106 and Heart Failure
| Article | Year |
|---|---|
Comparison of the action potential prolonging and positive inotropic activity of DPI 201-106 and BDF 9148 in human ventricular myocardium.
Topics: Action Potentials; Aged; Azetidines; Biological Transport; Calcium; Cardiotonic Agents; Carrier Prot | 1994 |
Inotropic response to DPI 201-106 in the failing human heart.
Topics: Adenosine; Adult; Aged; Aging; Calcium; Carbachol; Electric Stimulation; Female; Heart Failure; Hemo | 1989 |
Screening of positive inotropic agents in isolated cardiac preparations from different sources.
Topics: Animals; Atrial Function; Calcium; Cardiotonic Agents; Drug Evaluation, Preclinical; Heart; Heart Fa | 1989 |
Haemodynamic effects of DPI 201-106, following single intravenous dose administration to patients with moderate cardiac failure.
Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output; Heart Failure; Hemodynamics; Humans; Infusions | 1988 |