Page last updated: 2024-10-26

doxylamine and Pyloric Stenosis

doxylamine has been researched along with Pyloric Stenosis in 9 studies

Doxylamine: Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.

Pyloric Stenosis: Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.

Research Excerpts

ExcerptRelevanceReference
"Doxylamine-pyridoxine is the first-line agent for the treatment of nausea and vomiting of pregnancy (NVP) according to Canadian guidelines, and this combination is commonly prescribed to pregnant women."7.80Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? ( Chin, J; Persaud, N; Walker, M, 2014)
"Doxylamine-pyridoxine is the first-line agent for the treatment of nausea and vomiting of pregnancy (NVP) according to Canadian guidelines, and this combination is commonly prescribed to pregnant women."3.80Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? ( Chin, J; Persaud, N; Walker, M, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Persaud, N1
Chin, J1
Walker, M1
Louik, C2
Mitchell, AA2
Aselton, P1
Jick, H1
Chentow, SJ1
Perera, DR1
Hunter, JR1
Rothman, KJ1
Schwingl, PJ1
Rosenberg, L1
Shapiro, S1
Eskenazi, B1
Bracken, MB1
Jick, SS1
Garrison, JM1
Jedd, MB1
Melton, LJ1
Griffin, MR1
Kaufman, B1
Hoffman, AD1
Broughton, D1
O'Brien, PC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022[NCT06055192]200 participants (Anticipated)Observational2023-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for doxylamine and Pyloric Stenosis

ArticleYear
Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy?
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2014, Volume: 36, Issue:4

    Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans

2014
Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis.
    Obstetrics and gynecology, 2003, Volume: 101, Issue:4

    Topics: Anti-Bacterial Agents; Confounding Factors, Epidemiologic; Dicyclomine; Doxylamine; Drug Combination

2003
Pyloric stenosis and maternal Bendectin exposure.
    American journal of epidemiology, 1984, Volume: 120, Issue:2

    Topics: Adult; Dicyclomine; Doxylamine; Drug Combinations; Drug Prescriptions; Female; Follow-Up Studies; Hu

1984
Bendectin and pyloric stenosis.
    FDA drug bulletin, 1983, Volume: 13, Issue:2

    Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy;

1983
Birth defects in relation to Bendectin use in pregnancy. II. Pyloric stenosis.
    American journal of obstetrics and gynecology, 1983, Dec-01, Volume: 147, Issue:7

    Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hyperemesis

1983
Bendectin and pyloric stenosis in infants.
    American journal of obstetrics and gynecology, 1983, Dec-15, Volume: 147, Issue:8

    Topics: Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange

1983
Bendectin (Debendox) as a risk factor for pyloric stenosis.
    American journal of obstetrics and gynecology, 1982, Dec-15, Volume: 144, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defect

1982
Discontinuation of Bendectin.
    American journal of public health, 1988, Volume: 78, Issue:3

    Topics: Adult; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; P

1988
Factors associated with infantile hypertrophic pyloric stenosis.
    American journal of diseases of children (1960), 1988, Volume: 142, Issue:3

    Topics: Birth Order; Breast Feeding; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hypertrophy

1988