Page last updated: 2024-10-26

doxylamine and Drug Overdose

doxylamine has been researched along with Drug Overdose in 12 studies

Doxylamine: Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to investigate the associative factors of rhabdomyolysis in patients with doxylamine overdose who had normal creatine phosphokinase levels at admission."7.77The associative factors of delayed-onset rhabdomyolysis in patients with doxylamine overdose. ( Jeong, SH; Jeong, WJ; Kim, HJ; Kim, JH; Kim, SH; Oh, SH; Park, KN; Wee, JH; Youn, CS, 2011)
"The objective of this prospective study was to identify risk factors for developing rhabdomyolysis in patients with doxylamine overdose."7.74Risk factors for rhabdomyolysis following doxylamine overdose. ( Jo, YI; Koh, SY; Lee, JH; Lee, SM; Park, JH; Seo, TH; Song, JO, 2007)
"Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines."7.68Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993)
"Rhabdomyolysis and secondary acute renal failure are rare but potentially serious complications, making early recognition and treatment essential."5.31Doxylamine overdose as a potential cause of rhabdomyolysis. ( Fasseas, P; Leybishkis, B; Ryan, KF, 2001)
"Doxylamine succinate is an antihistaminic drugwith additional hypnotic, anticholinergic and local anesthetic effects first described in 1948."5.31Acute pancreatitis and acute renal failure complicating doxylamine succinate intoxication. ( Lee, ST; Lee, YD, 2002)
"The aim of this study was to investigate the associative factors of rhabdomyolysis in patients with doxylamine overdose who had normal creatine phosphokinase levels at admission."3.77The associative factors of delayed-onset rhabdomyolysis in patients with doxylamine overdose. ( Jeong, SH; Jeong, WJ; Kim, HJ; Kim, JH; Kim, SH; Oh, SH; Park, KN; Wee, JH; Youn, CS, 2011)
"The objective of this prospective study was to identify risk factors for developing rhabdomyolysis in patients with doxylamine overdose."3.74Risk factors for rhabdomyolysis following doxylamine overdose. ( Jo, YI; Koh, SY; Lee, JH; Lee, SM; Park, JH; Seo, TH; Song, JO, 2007)
"Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines."3.68Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993)
" We report a case of a suicide attempt in a young adult male where ingestion of the antihistamines diphenhydramine and doxylamine was complicated by non-traumatic rhabdomyolysis and acute renal failure."3.68Non-traumatic rhabdomyolysis complicating antihistamine overdose. ( Dolgin, J; Frankel, D; Murray, BM, 1993)
"Doxylamine succinate is a commonly used antihistamine for respiratory allergies including allergic rhinitis as well as for the management of insomnia."1.48Doxylamine succinate overdose: Slurred speech and visual hallucination. ( Derinöz-Güleryüz, O, 2018)
"Rhabdomyolysis and secondary acute renal failure are rare but potentially serious complications, making early recognition and treatment essential."1.31Doxylamine overdose as a potential cause of rhabdomyolysis. ( Fasseas, P; Leybishkis, B; Ryan, KF, 2001)
"Doxylamine succinate is an antihistaminic drugwith additional hypnotic, anticholinergic and local anesthetic effects first described in 1948."1.31Acute pancreatitis and acute renal failure complicating doxylamine succinate intoxication. ( Lee, ST; Lee, YD, 2002)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's4 (33.33)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, E1
Choi, YH1
Lim, JY1
Lee, J1
Lee, DH1
Derinöz-Güleryüz, O1
Dickson, AJ1
Vorce, SP1
Levine, B1
Past, MR1
Kim, HJ1
Oh, SH1
Youn, CS1
Wee, JH1
Kim, JH1
Jeong, WJ1
Kim, SH1
Jeong, SH1
Park, KN1
Carrascosa, MF1
Caviedes, JR1
Lucena, MI1
Cuadrado-Lavín, A1
Khosla, U1
Ruel, KS1
Hunt, DP1
Jo, YI1
Song, JO1
Park, JH1
Koh, SY1
Lee, SM1
Seo, TH1
Lee, JH1
Soto, LF1
Miller, CH1
Ognibere, AJ1
Frankel, D1
Dolgin, J1
Murray, BM1
Siek, TJ1
Dunn, WA1
Leybishkis, B1
Fasseas, P1
Ryan, KF1
Lee, YD1
Lee, ST1

Trials

1 trial available for doxylamine and Drug Overdose

ArticleYear
The effect of early urine alkalinization on occurrence rhabdomyolysis and hospital stay in high dose doxylamine ingestion.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:7

    Topics: Adult; Antidotes; Buffers; Charcoal; Doxylamine; Drug Overdose; Drug Therapy, Combination; Female; F

2018

Other Studies

11 other studies available for doxylamine and Drug Overdose

ArticleYear
Doxylamine succinate overdose: Slurred speech and visual hallucination.
    The Turkish journal of pediatrics, 2018, Volume: 60, Issue:4

    Topics: Adolescent; Cholinesterase Inhibitors; Doxylamine; Drug Overdose; Female; Hallucinations; Histamine

2018
Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:3

    Topics: Amphetamine-Related Disorders; Chromatography, Gas; Codeine; Doxylamine; Drug Overdose; Fatal Outcom

2010
The associative factors of delayed-onset rhabdomyolysis in patients with doxylamine overdose.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:8

    Topics: Adult; Antiemetics; Chi-Square Distribution; Creatine Kinase; Doxylamine; Drug Overdose; Female; Hea

2011
Syndrome of inappropriate antidiuresis in doxylamine overdose.
    BMJ case reports, 2012, Nov-19, Volume: 2012

    Topics: Aged; Dose-Response Relationship, Drug; Doxylamine; Drug Overdose; Female; Glasgow Coma Scale; Human

2012
Antihistamine-induced rhabdomyolysis.
    Southern medical journal, 2003, Volume: 96, Issue:10

    Topics: Adult; Diphenhydramine; Doxylamine; Drug Overdose; Histamine H1 Antagonists; Humans; Male; Rhabdomyo

2003
Risk factors for rhabdomyolysis following doxylamine overdose.
    Human & experimental toxicology, 2007, Volume: 26, Issue:8

    Topics: Acute Kidney Injury; Adult; Creatinine; Dose-Response Relationship, Drug; Doxylamine; Drug Overdose;

2007
Severe rhabdomyolysis after doxylamine overdose.
    Postgraduate medicine, 1993, Volume: 93, Issue:8

    Topics: Adult; Bicarbonates; Creatine Kinase; Doxylamine; Drug Overdose; Epilepsy, Tonic-Clonic; Histamine H

1993
Non-traumatic rhabdomyolysis complicating antihistamine overdose.
    Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:3

    Topics: Acute Kidney Injury; Adult; Blood Urea Nitrogen; Creatinine; Diphenhydramine; Doxylamine; Drug Overd

1993
Documentation of a doxylamine overdose death: quantitation by standard addition and use of three instrumental techniques.
    Journal of forensic sciences, 1993, Volume: 38, Issue:3

    Topics: Calibration; Chromatography, High Pressure Liquid; Doxylamine; Drug Overdose; Gas Chromatography-Mas

1993
Doxylamine overdose as a potential cause of rhabdomyolysis.
    The American journal of the medical sciences, 2001, Volume: 322, Issue:1

    Topics: Acute Kidney Injury; Adult; Doxylamine; Drug Overdose; Histamine H1 Antagonists; Humans; Male; Nonpr

2001
Acute pancreatitis and acute renal failure complicating doxylamine succinate intoxication.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:3

    Topics: Acute Disease; Acute Kidney Injury; Adult; Diagnosis, Differential; Doxylamine; Drug Overdose; Emerg

2002